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Antimicrobial Peptide Brevivin-1RL1 from Frog Skin Secretion Induces Apoptosis and Necrosis of Tumor Cells 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 7, 页码: 2059
作者:  Ju,Xiaoman;  Fan,Dongmei;  Kong,Lingmei;  Yang,Qihong;  Zhu,Yiying;  Zhang,Shaohua;  Su,Guifeng;  Li,Yan
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antimicrobial peptide  Brevivin-1RL1  apoptosis  necrosis  caspase  anticancer  BULLFROG  PHOSPHATIDYLSERINE  MECHANISMS  ANTITUMOR  SURFACE  
Chaetolactam A, an Azaphilone Derivative from the Endophytic Fungus Chaetomium sp. g1 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2021, 卷号: 86, 期号: 1, 页码: 475-483
作者:  Zu,Wen-Yu;  Tang,Jian-Wei;  Hu,Kun;  Zhou,Yuan-Fei;  Gou,Lei-Lei;  Su,Xiao-Zheng;  Lei,Xinxiang;  Sun,Han-Dong;  Puno,Pema-Tenzin
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MASS-SPECTROMETRY  A-D  CASPASE-3  H-1  
Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala 期刊论文
RSC ADVANCES, 2014, 卷号: 4, 期号: 96, 页码: 53725-53729
作者:  Wang, Kai-Bo;  Yuan, Chun-Mao;  Xue, Chun-Mei;  Li, Da-Hong;  Jing, Yong-Kui;  He, Hong-Ping;  Hao, Xiao-Jiang;  Di, Ying-Tong;  Li, Zhan-Lin;  Hua, Hui-Ming;  Hua,HM (reprint author),Shenyang Pharmaceut Univ,Key Lab Struct Based Drug Design & Discovery,Minist Educ,Shenyang 110016,Peoples R China.
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Liverwort Lepidolaena-clavigera  Caspase-3 Inhibitory-activity  Sp No 27  Absolute-configuration  Aspergillus-fumigatus  Tetracyclic Skeleton  Chaetomium-elatum  Phialophora  Metabolites  Acetals  
Anti-tumour activity of longikaurin A (LK-A), a novel natural diterpenoid, in nasopharyngeal carcinoma 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 卷号: 11, 期号: 1, 页码: 200
作者:  Zou, Qing-Feng;  Du, Ji-Ke;  Zhang, Hua;  Wang, Hong-Bo;  Hu, Ze-Dong;  Chen, Shu-Peng;  Du, Yong;  Li, Man-Zhi;  Xie, Dan;  Zou, Juan;  Sun, Han-Dong;  Pu, Jian-Xin;  Zeng, Mu-Sheng
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Longikaurin a (Lk-a)  Apoptosis  Caspase  Nasopharyngeal Carcinoma  
Small compound 6-O-angeloylplenolin induces caspase-dependent apoptosis in human multiple myeloma cells 期刊论文
ONCOLOGY LETTERS, 2013, 卷号: 6, 期号: 2, 页码: 556-558
作者:  Liu, Ying;  Dong, Ying;  Zhang, Bo;  Cheng, Yong-Xian
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6-o-angeloylplenolin  Multiple Myeloma  Apoptosis  Caspase  
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
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One Of The Major compOnents Isolated From The Traditional  2-methyl-1  Chinese Medicine Rubia Yunnanensis  3  Exhibited Inhibitory Activity On The proliferatiOn Of Several  6-trihydroxy-9  HumAn CAncer Cell Lines. The Results From An Annexin V-fitc (fluoresein-5-isothiocyAnate) Apoptosis Assay  10-anthraquinone (Mta)  And Dna Content Analysis Showed That Mta Exerted Cytotoxicity Via Apoptosis Induction And G2/m Cell Cycle  Arrest In Human Cervical carcInoma Hela Cells. Further  Mta Was Found To Induce apopTosis Of Hela Cells  Through The MITochondria-mediated Pathway. It Caused The Translocation Of Bax To The mITochondria And  Release Of Cytochrome c Into The Cytosol  Which Caused The Cleavage Of Caspase And Poly(Adp-ribose)  Polymerase And Finally Triggered The Apoptosis. furThermore  The P53/p21/cdc2-cyclin B1 Signaling Was  Found Related To The G2/m Arrest Caused By Mta. The Over-expression Of P21 And Down-expression Of  Cyclin B1 Caused By Mta Inactivated The cdc2-Cyclin B1 Complex Of G2/m Checkpoint And Finally Caused  The G2/m Arrest In Hela Cells. ThIs Study Demonstrated That Mta Is a Potential Anti-cancer Component Of  R. Yunnanensis  a Folk Anti-cancer Herb Used In Yunnan  China.  
Peroxisome-derived lipids are self antigens that stimulate invariant natural killer T cells in the thymus 期刊论文
NATURE IMMUNOLOGY, 2012, 卷号: 13, 期号: 5, 页码: 474-U73
作者:  Federica Facciotti;  Gundimeda S Ramanjaneyulu;  Marco Lepore;  Sebastiano Sansano;  Marco Cavallari;  Magdalena Kistowska;  Sonja Forss-Petter;  Guanghui Ni;  Alessia Colone;  Amit Singhal;  Johannes Berger;  Chengfeng Xia;  Lucia Mori;  Gennaro De Libero
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Anticancer Drug  Garcinia Oligantha  Xanthone  Apoptosis  Caspase-3  Derivatives  Activation  
Identification and evaluation of apoptotic compounds from Garcinia oligantha 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2012, 卷号: 22, 期号: 6, 页码: 2350-2353
作者:  Gao, Xue-Mei;  Yu, Ting;  Cui, Ming-zhu;  Pu, Jian-Xin;  Du, Xue;  Han, Quan-bin;  Hu, Qiu-fen;  Liu, Tian-Cheng;  Luo, Kathy Qian;  Xu, Hong-Xi
Adobe PDF(360Kb)  |  收藏  |  浏览/下载：438/142  |  提交时间：2012/06/07
Anticancer Drug  Garcinia Oligantha  Xanthone  Apoptosis  Caspase-3  
Cycloartane Triterpenoids from Cimicifuga yunnanensis induce Apoptosis of Breast Cancer Cells (MCF7) via p53-dependent Mitochondrial Signaling Pathway 期刊论文
PHYTOTHERAPY RESEARCH, 2011, 卷号: 25, 期号: 1, 页码: 17-24
作者:  Fang, Zhong-Ze;  Nian, Yin;  Li, Wei;  Wu, Jing-Jing;  Ge, Guang-Bo;  Dong, Pei-Pei;  Zhang, Yan-Yan;  Qiu, Ming-Hua;  Liu, Lei;  Yang, Ling
Adobe PDF(982Kb)  |  收藏  |  浏览/下载：391/130  |  提交时间：2012/04/10
Cycloartane Triterpenoids  Mcf7  P53  Apoptosis  Mitochondrial Membrane Potential  Caspase-7  
Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection 期刊论文
TALANTA, 2010, 卷号: 82, 期号: 4, 页码: 1521-1527
作者:  Han, Quan-Bin;  Yu, Ting;  Lai, Fanny;  Zhou, Yan;  Feng, Chao;  Wang, Wei-Na;  Fu, Xiao-Hui;  Lau, Clara Bik-San;  Luo, Kathy Q.;  Xu, Hong-Xi;  Sun, Han-Dong;  Fung, Kwok-Pui;  Leung, Ping-Chung
Adobe PDF(487Kb)  |  收藏  |  浏览/下载：395/148  |  提交时间：2012/03/21
Analytical High-speed Counter-current Chromatography  Caspase-3 Biosensor  Isodon Eriocalyx  Apoptosis Inducer  Eriocalyxin b