| Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala | |
Wang, Kai-Bo1; Yuan, Chun-Mao2; Xue, Chun-Mei1; Li, Da-Hong1; Jing, Yong-Kui3; He, Hong-Ping2; Hao, Xiao-Jiang2 ; Di, Ying-Tong2; Li, Zhan-Lin1; Hua, Hui-Ming1; Hua,HM (reprint author),Shenyang Pharmaceut Univ,Key Lab Struct Based Drug Design & Discovery,Minist Educ,Shenyang 110016,Peoples R China.
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| 2014 | |
| 发表期刊 | RSC ADVANCES
 |
| ISSN | 2046-2069 |
| 卷号 | 4期号:96页码:53725-53729 |
| 摘要 | Pegaharmalines A (1) and B (2), two novel beta-carboline alkaloids with unprecedented carbon skeletons, were isolated from the seeds of Peganum harmala. Their structures were determined by spectroscopic methods and the absolute configuration of 1 was elucidated by CD analysis. 1 and 2 exhibited significant cytotoxicities on HL-60 cells with IC50 values of 9.4 and 13.6 mu M, respectively. |
| 关键词 | Liverwort Lepidolaena-clavigera Caspase-3 Inhibitory-activity Sp No 27 Absolute-configuration Aspergillus-fumigatus Tetracyclic Skeleton Chaetomium-elatum Phialophora Metabolites Acetals |
| 学科领域 | Chemistry, Multidisciplinary |
| DOI | 10.1039/c4ra07985j |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000344468800043 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/18484 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 通讯作者 | Hua,HM (reprint author),Shenyang Pharmaceut Univ,Key Lab Struct Based Drug Design & Discovery,Minist Educ,Shenyang 110016,Peoples R China. |
| 作者单位 | 1.Shenyang Pharmaceut Univ, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China 3.Mt Sinai Sch Med, Dept Med, New York, NY 10029 USA |
| 推荐引用方式 GB/T 7714 | Wang, Kai-Bo,Yuan, Chun-Mao,Xue, Chun-Mei,et al. Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala[J]. RSC ADVANCES,2014,4(96):53725-53729. |
| APA | Wang, Kai-Bo.,Yuan, Chun-Mao.,Xue, Chun-Mei.,Li, Da-Hong.,Jing, Yong-Kui.,...&Hua,HM .(2014).Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala.RSC ADVANCES,4(96),53725-53729. |
| MLA | Wang, Kai-Bo,et al."Pegaharmalines A and B, two novel beta-carboline alkaloids with unprecedented carbon skeletons from Peganum harmala".RSC ADVANCES 4.96(2014):53725-53729. |
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| wang2014.pdf（585KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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