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Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 106375
作者:  Peng,Xingrong;  Luo,Rongcan;  Ran,Xiaoqian;  Guo,Yarong;  Yao,Yong-Gang;  Qiu,Minghua
浏览  |  Adobe PDF(3003Kb)  |  收藏  |  浏览/下载：100/15  |  提交时间：2024/07/22
Ganoderma  Ganoderma applanatum  Triterpenoid  Autophagy  Tau pathology  Alzheimer?s disease  LANOSTANE-TYPE TRITERPENOIDS  ALZHEIMERS-DISEASE  FRUITING BODIES  NEURODEGENERATION  ACID  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
浏览  |  Adobe PDF(1471Kb)  |  收藏  |  浏览/下载：121/27  |  提交时间：2024/07/25
UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
New Monoterpenoid Indole Alkaloids from Tabernaemontana crassa Inhibit beta-Amyloid42 Production and Phospho-Tau (Thr217) 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1487
作者:  Li,Sheng;  Han,Ling-Ling;  Huang,Ke-Pu;  Ma,Ye-Han;  Guo,Ling-Li;  Guo,Yarong;  Ran,Xiaoqian;  Yao,Yong-Gang;  Hao,Xiao-Jiang;  Luo,Rongcan;  Zhang,Yu
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Tabernaemontana crassa  monoterpenoid indole alkaloids  A beta 42  phospho-tau (Thr217)  Alzheimer's disease  ALZHEIMERS-DISEASE  BISINDOLE ALKALOIDS  CDK5  GEMFIBROZIL  PREVENTION  ALGORITHM  AUTOPHAGY  MODELS  PLANTS  MOUSE  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
浏览  |  Adobe PDF(11343Kb)  |  收藏  |  浏览/下载：141/22  |  提交时间：2024/05/09
euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS  
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway 期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:  Ran,Xiaoqian;  Lu,Qing-Yun;  Li,Ying-Yao;  Pu,Xue-Xue;  Guo,Yarong;  Yuan,Ming-Rui;  Guan,Shi-Peng;  Sun,Mao;  Jiao,Lijin;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang;  Luo,Rongcan
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Euphorbia peplus L  Euphorbiaceae  Ent-abietane diterpenoid  Euphejolkinolide A  Autophagy-lysosomal pathway  ALZHEIMERS-DISEASE  TAU PATHOLOGY  NEURODEGENERATION  DITERPENOIDS  INHIBITION  MECHANISMS  APOPTOSIS  CELASTROL  PROTEIN  SYSTEM  
Acetylcholineestarase-Inhibiting Alkaloids from Lycoris radiata Delay Paralysis of Amyloid Beta-Expressing Transgenic C. elegans CL4176 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 5, 页码: e63874
作者:  Xin, Lijuan;  Yamujala, Ritupriya;  Wang, Yuehu;  Wang, Huan;  Wu, Wen-Hsuan;  Lawton, Michael A.;  Long, Chunlin;  Di, Rong
浏览  |  Adobe PDF(760Kb)  |  收藏  |  浏览/下载：462/88  |  提交时间：2013/07/24
Alzheimers-disease  Caenorhabditis-elegans  Acetylcholinesterase Inhibitors  Amaryllidaceae Alkaloids  Oxidative Stress  Pc12 Cells  Peptide  Genes  Peroxide  Hypothesis  
An Improved Chloroplast DNA Extraction Procedure for Whole Plastid Genome Sequencing 期刊论文
PLOS ONE, 2012, 卷号: 7, 期号: 2, 页码: e31468
作者:  Shi, Chao;  Hu, Na;  Huang, Hui;  Gao, Ju;  Zhao, You-Jie;  Gao, Li-Zhi
Adobe PDF(542Kb)  |  收藏  |  浏览/下载：373/126  |  提交时间：2012/06/07
Itraq Technology  Neural Cell Adhesion Molecule 1  Neurodegenerative Diseases  Tianma  Gastrodia-elata Blume  Prolyl Isomerase Pin1  Neurodegenerative Diseases  Alzheimers-disease  Neurotrophic Factor  Retinoic Acid  Triosephosphate Isomerase  Cis/trans Isomerases  Ether Fraction  Sh-sy5y Cells  
Two new pregnanone derivatives with strong cytotoxic activity from Pachysandra arillaris 期刊论文
CHEMISTRY & BIODIVERSITY, 2005, 卷号: 2, 期号: 7, 页码: 866-871
作者:  Qiu, MH;  Nakamura, N;  Min, BS;  Hattori, M
Adobe PDF(175Kb)  |  收藏  |  浏览/下载：352/102  |  提交时间：2012/03/21
Relative Configuration  L-755  Alzheimers-disease  807  Militarinone-a  Metabolites  Targets