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Discovery of potential novel TRPC5 inhibitors by virtual screening and bioassay 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 94, 页码: 117477
作者:  Shen,Meiling;  Li,Lingfeng;  Li,Yue;  Gu,Xi;  Bai,Longhui;  Xia,Chengfeng;  Xiong,Wenyong;  Zuo,Zhili
浏览  |  Adobe PDF(6089Kb)  |  收藏  |  浏览/下载：48/15  |  提交时间：2024/07/22
TRPC5  Inhibitors  Virtual screening  Ca 2+channel  CHANNELS  IDENTIFICATION  PERMEABILITY  CALCIUM  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(4466Kb)  |  收藏  |  浏览/下载：74/11  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Identification and screening of novel diterpenoids from roasted arabica coffee in the regulation of lipid content in white adipocytes 期刊论文
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 11, 页码: 5138-5150
作者:  Wang,Qian;  Hu,Guilin;  Lu,Qian;  Hong,Defu;  Al-Romaima,Abdulbaset;  Qiu,Minghua;  Xiong,Wenyong
浏览  |  Adobe PDF(5144Kb)  |  收藏  |  浏览/下载：70/11  |  提交时间：2024/07/31
ACCUMULATION  CAFESTOL  KAHWEOL  BEANS  DIFFERENTIATION  
Anti-Adipogenic Lanostane-Type Triterpenoids from the Edible and Medicinal Mushroom Ganoderma applanatum 期刊论文
JOURNAL OF FUNGI, 2022, 卷号: 8, 期号: 4, 页码: 331
作者:  Peng, Xing-Rong;  Wang, Qian;  Su, Hai-Guo;  Zhou, Lin;  Xiong, Wen-Yong;  Qiu, Ming-Hua
浏览  |  Adobe PDF(4854Kb)  |  收藏  |  浏览/下载：78/11  |  提交时间：2024/04/30
Ganoderma applanatum  lanostane triterpenoid  Mosher's method  anti-adipogenesis activity  structure-activity relationship  APOPTOSIS  LUCIDUM  INFLAMMATION  METABOLISM  EXTRACTS  PROVIDE  BODY  
Hepatic RACK1 deletion disturbs lipid and glucose homeostasis independently of insulin resistance 期刊论文
JOURNAL OF ENDOCRINOLOGY, 2022, 卷号: 254, 期号: 3, 页码: 151-165
作者:  Qin, Wanying;  Zhang, Ting;  Ge, Mingxia;  Zhou, Huimin;  Xu, Yuhui;  Mu, Rongfang;  Huang, Chaoguang;  Liu, Daowei;  Huang, Bangrui;  Wang, Qian;  Kong, Qinghua;  Kong, Qingpeng;  Li, Fei;  Xiong, Wenyong
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RACK1  bile acid  glucose metabolism  insulin sensitivity  ENDOPLASMIC-RETICULUM STRESS  C-KINASE 1  HEPATOCELLULAR-CARCINOMA  STEROL 12-ALPHA-HYDROXYLASE  DOWN-REGULATION  ER STRESS  KAPPA-B  RECEPTOR  ACTIVATION  GROWTH  
anti-adipogenic adamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum subsessile (vol 147, 104755, 2020) 期刊论文
FITOTERAPIA, 2021, 卷号: 149, 页码: 104791
作者:  Cao,Tuan-Wu;  Liu,Xia;  Ye,Yan-Song;  Zhou,Hui-Min;  Liu,Dao-Wei;  Xiong,Wen-Yong;  Xu,Gang
收藏  |  浏览/下载：132/0  |  提交时间：2022/04/02
Functional triterpenoids from medicinal fungi Ganoderma applanatum: A continuous search for antiadipogenic agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104977
作者:  Su,Hai-Guo;  Wang,Qian;  Zhou,Lin;  Peng,Xing-Rong;  Xiong,Wen-Yong;  Qiu,Ming -Hua
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Ganoderma applanatum  Lanostane triterpenoids  Antiadipogenic effects  LANOSTANE-TYPE TRITERPENOIDS  ACID  
Identified Three Interferon Induced Proteins as Novel Biomarkers of Human Ischemic Cardiomyopathy 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 卷号: 22, 期号: 23, 页码: 13116
作者:  Chen,Cheng;  Tian,Jiao;  He,Zhicheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(7773Kb)  |  收藏  |  浏览/下载：141/36  |  提交时间：2022/04/02
ischemic cardiomyopathy  heart failure  WGCNA  interferon stimulated genes  IFIT2  3  MYOCARDIAL-INFARCTION  NETWORK ANALYSIS  GENE  
FPR2-based anti-inflammatory and anti-lipogenesis activities of novel meroterpenoid dimers from Ganoderma 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105338
作者:  Peng,Xing-Rong;  Wang,Qian;  Wang,Hui-Rong;  Hu,Kun;  Xiong,Wen-Yong;  Qiu,Ming-Hua
浏览  |  Adobe PDF(7004Kb)  |  收藏  |  浏览/下载：142/28  |  提交时间：2022/04/02
Ganoderma applanatum  Meroterpenoid dimers  Molecular docking  Anti-lipogenesis  FPR2-based inflammation  INDUCED INSULIN-RESISTANCE  ADIPOCYTE DIFFERENTIATION  OBESITY  INFLAMMATION  DEFICIENCY  MACROPHAGES  ACTIVATION  EXPRESSION  LIGAND  MICE  
Steaming Changes the Composition of Saponins of Panax notoginseng (Burk.) FH Chen That Function in Treatment of Hyperlipidemia and Obesity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
作者:  Wang, Qian;  Mu, Rong-Fang;  Liu, Xing;  Zhou, Hui-Min;  Xu, Yu-Hui;  Qin, Wan-Ying;  Yang, Chong-Ren;  Wang, Li-Bin;  Li, Hai-Zhou;  Xiong, Wen-Yong
浏览  |  Adobe PDF(14647Kb)  |  收藏  |  浏览/下载：199/46  |  提交时间：2021/01/05