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A new sesquiterpene synthase catalyzing the formation of (R)-fi-bisabolene from medicinal plant Colquhounia coccinea var. mollis and its anti-adipogenic and antibacterial activities 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 211, 页码: 113681
作者:  Li,De-Sen;  Shi,Lin-Lin;  Guo,Kai;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Liu,Yan;  Li,Sheng-Hong
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Sesquiterpenoids  Sesquiterpene synthases  (R)-fi-bisabolene  Colquhounia coccinea var  mollis  Anti-adipogenic activity  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  FUNCTIONAL EXPRESSION  BETA-BISABOLENE  ESSENTIAL OILS  BIOSYNTHESIS  IDENTIFICATION  CYTOTOXICITY  CLONING  
ZmMPK6 and ethylene signalling negatively regulate the accumulation of anti-insect metabolites DIMBOA and DIMBOA-Glc in maize inbred line A188 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 4, 页码: 2273-2287
作者:  Zhang,Cuiping;  Li,Jing;  Li,Sen;  Ma,Canrong;  Liu,Hui;  Wang,Lei;  Qi,Jinfeng;  Wu,Jianqiang
收藏  |  浏览/下载：192/0  |  提交时间：2022/04/02
DIMBOA  ethylene  herbivory  maize  MPK6  Mythimna separata  transcriptome  ACTIVATED PROTEIN-KINASE  NICOTIANA-ATTENUATA  ORAL SECRETIONS  JASMONIC ACID  TRANSCRIPTION FACTORS  EXPRESSION ANALYSIS  DEFENSE RESPONSES  APHID RESISTANCE  PLANT DEFENSES  BIOSYNTHESIS  
Characterization of defensive cadinenes and a novel sesquiterpene synthase responsible for their biosynthesis from the invasive Eupatorium adenophorum 期刊论文
NEW PHYTOLOGIST, 2021, 卷号: 229, 期号: 3, 页码: 1740-1754
作者:  Liu,Yan;  Luo,Shi-Hong;  Hua,Juan;  Li,De-Sen;  Ling,Yi;  Luo,Qian;  Li,Sheng-Hong
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cadinenes  defensive chemicals  Eupatorium adenophorum  sesquiterpenes  sesquiterpene synthase  NATURAL-PRODUCTS  FUNCTIONAL-CHARACTERIZATION  ABSOLUTE STEREOCHEMISTRY  TERPENE SYNTHASES  EXPRESSION  CLONING  EMISSION  LEAVES  GENES  9-OXO-10,11-DEHYDROAGERAPHORONE  
Immunosuppressive and Adipogenesis Inhibitory Sesterterpenoids with a Macrocyclic Ether System from Eurysolen gracilis 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 6, 页码: 2232-2237
作者:  Teng,Lin-Lin;  Mu,Rong-Fang;  Liu,Yan-Chun;  Xiao,Chao-Jiang;  Li,De-Sen;  Gao,Jian-Xiong;  Guo,Kai;  Li,Xiao-Nian;  Liu,Yan;  Zeng,Fang;  Li,Sheng-Hong
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Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
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A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
作者:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
浏览  |  Adobe PDF(2177Kb)  |  收藏  |  浏览/下载：177/69  |  提交时间：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Cloning and Functional Characterization of a Squalene Synthase from Paris polyphylla var. yunnanensis 期刊论文
CHEMISTRY & BIODIVERSITY, 2021, 卷号: 18, 期号: 7
作者:  Gao,Jian-Xiong;  Chen,Yue-Gui;  Li,De-Sen;  Lin,Liang;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(5087Kb)  |  收藏  |  浏览/下载：196/43  |  提交时间：2022/04/02
Paris polyphylla var  Yunnanensis  squalene synthase  steroidal saponins  squalene  in vitro enzymatic assay  MOLECULAR-CLONING  SAPONINS  EXPRESSION  GENE  GLYCOSIDES  PLANTS  SQS  
An extremely promiscuous terpenoid synthase from the Lamiaceae plant Colquhounia coccinea var. mollis catalyzes the formation of sester-/di-/sesqui-/mono-terpenoids 期刊论文
PLANT COMMUNICATIONS, 2021, 卷号: 2, 期号: 5, 页码: 100233
作者:  Li,De-Sen;  Hua,Juan;  Luo,Shi-Hong;  Liu,Yan-Chun;  Chen,Yue-Gui;  Ling,Yi;  Guo,Kai;  Liu,Yan;  Li,Sheng-Hong
浏览  |  Adobe PDF(2409Kb)  |  收藏  |  浏览/下载：147/36  |  提交时间：2022/04/02
terpenoid diversity  terpenoid synthase  promiscuous enzyme  sester-/di-/sesqui-/mono-terpenoids  Colquhounia coccinea var  mollis  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  DITERPENE SYNTHASE  LEUCOSCEPTRUM-CANUM  IDENTIFICATION  BRASSICACEAE  BIOLOGY  FAMILY  HARBOR  GENES  
Potent Antihyperuricemic Triterpenoids Based on Two Unprecedented Scaffolds from the Leaves of Alstonia scholaris 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 11, 页码: 4158-4162
作者:  Hu,Bin-Yuan;  Zhao,Yun-Li;  Xiong,Deng-Sen;  He,Ying-Jie;  Zhou,Zhong-Shun;  Zhu,Pei-Feng;  Wang,Zhao-Jie;  Wang,Yong-Liang;  Zhao,Li-Xing;  Luo,Xiao-Dong
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Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：102/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN