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Discovery and bioinspired total syntheses of unprecedented sesquiterpenoid dimers unveiled bifurcating [4+2] cycloaddition and target differentiation of enantiomers 期刊论文
CHEMICAL SCIENCE, 2024, 卷号: 15, 期号: 4
作者:  He, Tao-Bin;  Yan, Bing-Chao;  Zhou, Yuan-Fei;  Sang, Yue-Qian;  Li, Xiao-Nian;  Sun, Han-Dong;  Wang, Chu;  Xue, Xiao-Song;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(3322Kb)  |  收藏  |  浏览/下载：125/37  |  提交时间：2024/05/09
DIELS-ALDER REACTION  BIOMIMETIC SYNTHESES  EFFICIENT ACCESS  DEHYDROGENATION  CYCLOHEXANONES  BIOSYNTHESIS  CONVERSION  OXIDATION  DYNAMICS  PHENOLS  
Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载：69/19  |  提交时间：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Phylogenomic insights into the origin and evolutionary history of evergreen broadleaved forests in East Asia under Cenozoic climate change 期刊论文
MOLECULAR ECOLOGY, 2023, 卷号: 32, 期号: 11, 页码: 2850-2868
作者:  Qin,Sheng-Yuan;  Zuo,Zheng-Yu;  Guo,Cen;  Du,Xin-Yu;  Liu,Shui-Yin;  Yu,Xiang-Qin;  Xiang,Xiao-Guo;  Rong,Jun;  Liu,Bing;  Liu,Zhi-Fang;  Ma,Peng-Fei;  Li,De-Zhu
浏览  |  Adobe PDF(12802Kb)  |  收藏  |  浏览/下载：53/11  |  提交时间：2024/07/10
East Asian monsoon  evergreen broadleaved forests  genome resequencing  Lauraceae  Litsea complex  single-nucleotide variants  SOUTHERN CHINA EVIDENCE  NORTHERN-HEMISPHERE  MOLECULAR PHYLOGENY  SPECIES RICHNESS  LITSEA COMPLEX  R PACKAGE  LAURACEAE  EOCENE  TERTIARY  BIOGEOGRAPHY  
Continuous genetic adaptation to high elevations of alpine bamboos in the Hengduan Mountains, Southwest China 期刊论文
JOURNAL OF SYSTEMATICS AND EVOLUTION, 2023
作者:  Luo,Li-Ying;  Jin,Gui-Hua;  Ma,Peng-Fei;  Li,De-Zhu
浏览  |  Adobe PDF(1348Kb)  |  收藏  |  浏览/下载：55/15  |  提交时间：2024/07/10
alpine bamboos  continuum evolution  Hengduan Mountains  high-elevation adaptation  transcriptome  HIGH-ALTITUDE ADAPTATION  PHYLOGENETIC ANALYSIS  EVOLUTION  DUPLICATIONS  GENERATION  POLYPLOIDY  SELECTION  
Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：48/11  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：55/15  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Total Syntheses of Cinchona Alkaloids via Photoredox-Catalyzed Deoxygenative Arylation 期刊论文
ORGANIC LETTERS, 2023
作者:  Li,Lei;  Yang,Hua-Fei;  Ding,Qian-Hui;  Wei,Kun;  Yang,Yu-Rong
浏览  |  Adobe PDF(1629Kb)  |  收藏  |  浏览/下载：44/12  |  提交时间：2024/07/10
ASYMMETRIC TOTAL SYNTHESES  ALPHA-ALLYLATION  FORMAL SYNTHESIS  QUININE  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
浏览  |  Adobe PDF(7289Kb)  |  收藏  |  浏览/下载：71/12  |  提交时间：2024/07/10
Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits 期刊论文
NATURE GENETICS, 2023
作者:  Huang,Yue;  He,Jiaxian;  Xu,Yuantao;  Zheng,Weikang;  Wang,Shaohua;  Chen,Peng;  Zeng,Bin;  Yang,Shuizhi;  Jiang,Xiaolin;  Liu,Zishuang;  Wang,Lun;  Wang,Xia;  Liu,Shengjun;  Lu,Zhihao;  Liu,Ziang;  Yu,Huiwen;  Yue,Jianqiang;  Gao,Junyan;  Zhou,Xianyan;  Long,Chunrui;  Zeng,Xiuli;  Guo,Yong-Jie;  Zhang,Wen-Fu;  Xie,Zongzhou;  Li,Chunlong;  Ma,Zhaocheng;  Jiao,Wenbiao;  Zhang,Fei;  Larkin,Robert M.;  Krueger,Robert R.;  Smith,Malcolm W.;  Ming,Ray;  Deng,Xiuxin;  Xu,Qiang
浏览  |  Adobe PDF(12192Kb)  |  收藏  |  浏览/下载：74/24  |  提交时间：2024/07/22
PHYLOGENETIC ANALYSIS  VACUOLAR PH  GENOME  RUTACEAE  ACCURATE  ORIGIN  TOOL  CLASSIFICATION  PROGRAM  RETROTRANSPOSONS  
Artemannuols A-C, novel sesquiterpenoid-flavonol hybrids with antihepatoma activity from Artemisia annua 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 26, 页码: 5451-5456
作者:  He,Xiao-Feng;  Wang,Meng-Fei;  Li,Tian-Ze;  Ma,Yun-Bao;  Chen,Ji-Jun
浏览  |  Adobe PDF(556Kb)  |  收藏  |  浏览/下载：56/10  |  提交时间：2024/07/25
Hepatocellular-carcinoma  Aggregation Pheromone  Bug