Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits

doi:10.1038/s41588-023-01516-6

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	Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits
	Huang,Yue; He,Jiaxian; Xu,Yuantao; Zheng,Weikang; Wang,Shaohua; Chen,Peng; Zeng,Bin; Yang,Shuizhi; Jiang,Xiaolin; Liu,Zishuang; Wang,Lun; Wang,Xia; Liu,Shengjun; Lu,Zhihao; Liu,Ziang; Yu,Huiwen; Yue,Jianqiang; Gao,Junyan; Zhou,Xianyan; Long,Chunrui; Zeng,Xiuli; Guo,Yong-Jie; Zhang,Wen-Fu; Xie,Zongzhou; Li,Chunlong; Ma,Zhaocheng; Jiao,Wenbiao; Zhang,Fei; Larkin,Robert M.; Krueger,Robert R.; Smith,Malcolm W.; Ming,Ray; Deng,Xiuxin; Xu,Qiang
	2023
发表期刊	NATURE GENETICS
ISSN	1546-1718
摘要	The orange subfamily (Aurantioideae) contains several Citrus species cultivated worldwide, such as sweet orange and lemon. The origin of Citrus species has long been debated and less is known about the Aurantioideae. Here, we compiled the genome sequences of 314 accessions, de novo assembled the genomes of 12 species and constructed a graph-based pangenome for Aurantioideae. Our analysis indicates that the ancient Indian Plate is the ancestral area for Citrus-related genera and that South Central China is the primary center of origin of the Citrus genus. We found substantial variations in the sequence and expression of the PH4 gene in Citrus relative to Citrus-related genera. Gene editing and biochemical experiments demonstrate a central role for PH4 in the accumulation of citric acid in citrus fruits. This study provides insights into the origin and evolution of the orange subfamily and a regulatory mechanism underpinning the evolution of fruit taste.
关键词	PHYLOGENETIC ANALYSIS VACUOLAR PH GENOME RUTACEAE ACCURATE ORIGIN TOOL CLASSIFICATION PROGRAM RETROTRANSPOSONS
DOI	10.1038/s41588-023-01516-6
收录类别	SCI
WOS记录号	WOS:001076418700001
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/75432
专题	中国科学院昆明植物研究所
推荐引用方式 GB/T 7714	Huang,Yue,He,Jiaxian,Xu,Yuantao,et al. Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits[J]. NATURE GENETICS,2023.
APA	Huang,Yue.,He,Jiaxian.,Xu,Yuantao.,Zheng,Weikang.,Wang,Shaohua.,...&Xu,Qiang.(2023).Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits.NATURE GENETICS.
MLA	Huang,Yue,et al."Pangenome analysis provides insight into the evolution of the orange subfamily and a key gene for citric acid accumulation in citrus fruits".NATURE GENETICS (2023).

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