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C-28 steroids from the fruiting bodies of Ganoderma resinaceum with potential anti-inflammatory activity 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 168, 页码: 8
作者:  Shi, Qiangqiang;  Huang, Yanjie;  Su, Haiguo;  Gao, Ya;  Peng, Xingrong;  Zhou, Lin;  Li, Xiaonian;  Qiu, Minghua
浏览  |  Adobe PDF(824Kb)  |  收藏  |  浏览/下载：258/77  |  提交时间：2020/03/26
Ganoderma resinaceum boud  Ganodermataceae  Ergostane-type  Steroids  Anti-inflammatory activity  
Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 982-987
作者:  Wang Lei;  Wang Li;  Zhou Zhi;  Wang Yong-Jiang;  Huang Jian-Ping;  Ma Ya-Tuan;  Liu Yang;  Huang Sheng-Xiong
浏览  |  Adobe PDF(563Kb)  |  收藏  |  浏览/下载：177/33  |  提交时间：2020/03/18
Streptomyces  Angucyclinones  Benz[a]anthracenes  Natural products  Immunosuppressive activity  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：212/33  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
Precise structures and anti-intrinsic tenase complex activity of three fucosylated glycosaminoglycans and their fragments 期刊论文
CARBOHYDRATE POLYMERS, 2019, 卷号: 224, 页码: 10
作者:  Cai, Ying;  Yang, Wenjiao;  Li, Xiaomei;  Zhou, Lutan;  Wang, Zhongjuan;  Lin, Lisha;  Chen, Dingyuan;  Zhao, Longyan;  Li, Zhongkun;  Liu, Shubai;  Yin, Ronghua;  Zuo, Zhili;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4714Kb)  |  收藏  |  浏览/下载：350/46  |  提交时间：2019/10/28
Fucosylated glycosaminoglycan  Oligosaccharide  Chemical structure  iXase  
Phlegmadine A: A Lycopodium Alkaloid with a Unique Cyclobutane Ring from Phlegmariurus phlegmaria 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2019, 卷号: 84, 期号: 17, 页码: 11301-11305
作者:  Zhang, Zhi-Jun;  Wang, Chen;  Wu, Xing-De;  Huang, Yan;  Zhou, Wen-Xia;  Zhao, Qin-Shi
浏览  |  Adobe PDF(1540Kb)  |  收藏  |  浏览/下载：225/22  |  提交时间：2019/11/07
Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin 期刊论文
CELL CHEMICAL BIOLOGY, 2019, 卷号: 26, 期号: 8, 页码: 1122-+
作者:  Zhu, Huifang;  Wang, Bin;  Kong, Lingmei;  An, Tao;  Li, Gentao;  Zhou, Hongyu;  Gong, Liang;  Zhao, Zhangxun;  Gong, Yaxiao;  Sun, Handong;  Puno, Pematenzin;  Li, Yan
浏览  |  Adobe PDF(4600Kb)  |  收藏  |  浏览/下载：202/38  |  提交时间：2019/10/14
Sense Ginsenosides From Ginsengs: Structure-Activity Relationship in Autophagy 期刊论文
NATURAL PRODUCT COMMUNICATIONS, 2019, 卷号: 14, 期号: 6, 页码: 10
作者:  Wu, Tao;  Kwaku, Osafo Raymond;  Li, Hai-Zhou;  Yang, Chong-Ren;  Ge, Long-Jiao;  Xu, Min
浏览  |  Adobe PDF(1069Kb)  |  收藏  |  浏览/下载：191/43  |  提交时间：2019/09/10
ginsengs  ginsenosides  structure-activity relationship  autophagy  
Discovery of novel indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors by virtual screening 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2019, 卷号: 78, 页码: 306-316
作者:  Zhou, Yeheng;  Peng, Jiale;  Li, Penghua;  Du, Haibo;  Li, Yaping;  Li, Yingying;  Zhang, Li;  Sun, Wei;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(2732Kb)  |  收藏  |  浏览/下载：269/44  |  提交时间：2019/03/25
IDO1  Molecular docking  HipHop pharmacophore  3D-QSAR  PAINS  
Glucoside Derivatives Of Podophyllotoxin: Synthesis, Physicochemical Properties, And Cytotoxicity 期刊论文
DRUG DESIGN DEVELOPMENT AND THERAPY, 2019, 卷号: 13, 页码: 3683-3692
作者:  Zi, Cheng-Ting;  Yang, Liu;  Kong, Qing-Hua;  Li, Hong-Mei;  Yang, Xing-Zhi;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao;  Zhou, Jun
Adobe PDF(3776Kb)  |  收藏  |  浏览/下载：180/24  |  提交时间：2020/03/26
podophyllotoxin  glucoside  synthesis  cytotoxicity  physicochemical properties  
Pharmacophore modeling, molecular docking and molecular dynamics simulations toward identifying lead compounds for Chk1 期刊论文
COMPUTATIONAL BIOLOGY AND CHEMISTRY, 2018, 卷号: 76, 页码: 53-60
作者:  Li, Yaping;  Peng, Jiale;  Zhou, Yeheng;  Li, Penghua;  Li, Yingying;  Liu, Xingyong;  Siddique, Abu Nasar;  Zhang, Li;  Zuo, Zhili
收藏  |  浏览/下载：150/0  |  提交时间：2018/11/12
Checkpoint kinase 1 inhibitor  Virtual screening  Pharmacophore modeling  Molecular docking  Molecular dynamics simulations