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Catalyzed Synthesis of 3-hydroxy-indol-2-one Derivatives as a Novel Phosphodiesterases 10 Inhibitor 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 33-34
作者:  Wu, Ya;  Li, Hao;  Yan, Jiao;  Cai, Qing;  Huang, Shengxiong;  Tang, Ying;  Ji, Yue;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：226/0  |  提交时间：2020/03/24
Cangumycins A-F, six new angucyclinone analogues with immunosuppressive activity from Streptomyces 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2019, 卷号: 17, 期号: 12, 页码: 982-987
作者:  Wang Lei;  Wang Li;  Zhou Zhi;  Wang Yong-Jiang;  Huang Jian-Ping;  Ma Ya-Tuan;  Liu Yang;  Huang Sheng-Xiong
浏览  |  Adobe PDF(563Kb)  |  收藏  |  浏览/下载：177/33  |  提交时间：2020/03/18
Streptomyces  Angucyclinones  Benz[a]anthracenes  Natural products  Immunosuppressive activity  
A unique spiro-beta-triazinedione-gamma-hydantoin type alkaloid with antiviral activity against tobacco mosaic virus from Streptomyces gamaensis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 18, 页码: 3215-3219
作者:  Guo, Xiaowei;  Wang, Jidong;  Su, Can;  Liu, Chongxi;  Ma, Xiao-Yan;  Yu, Zhiyin;  Li, Jiansong;  Wang, Xiangjing;  Xiang, Wensheng;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1243Kb)  |  收藏  |  浏览/下载：245/71  |  提交时间：2019/10/28
Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation 期刊论文
NATURE COMMUNICATIONS, 2019, 卷号: 10, 页码: 8
作者:  Huang, Jian-Ping;  Fang, Chengli;  Ma, Xiaoyan;  Wang, Li;  Yang, Jing;  Luo, Jianying;  Yan, Yijun;  Zhang, Yu;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1048Kb)  |  收藏  |  浏览/下载：239/61  |  提交时间：2019/10/28
Anti-inflammatory Effect of Pomelo Peel and Its Bioactive Coumarins 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 32, 页码: 8810-8818
作者:  Zhao, Yun-Li;  Yang, Xiong-Wu;  Wu, Bai-Fen;  Shang, Jian-Hua;  Liu, Ya-Ping;  Zhi-Dai;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1099Kb)  |  收藏  |  浏览/下载：174/50  |  提交时间：2019/10/14
C. grandis  coumarins  anti-inflammatory effect  lipopolysaccharide  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：253/73  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427
作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui;  Hu, Jing;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4461Kb)  |  收藏  |  浏览/下载：249/70  |  提交时间：2019/09/10
glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene  
Dimeric Pyranonaphthoquinone Glycosides with Anti-HIV and Cytotoxic Activities from a Soil-Derived Streptomyces 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2019, 卷号: 82, 期号: 7, 页码: 1813-1819
作者:  He, Xin;  Wang, Yongjiang;  Luo, Rong-Hua;  Yang, Liu-Meng;  Wang, Li;  Guo, Dale;  Yang, Jing;  Deng, Yun;  Zheng, Yong-Tang;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(631Kb)  |  收藏  |  浏览/下载：248/57  |  提交时间：2019/09/10
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 2, 页码: 177-182
作者:  Zhang, Zhouxin;  Cao, Pei;  Shang, Ning-Ning;  Yang, Jing;  Wang, Li;  Yan, Yijun;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(990Kb)  |  收藏  |  浏览/下载：215/39  |  提交时间：2019/03/18
A new actinomycin Z analogue with an additional oxygen bridge between chromophore and beta-depsipentapeptide from Streptomyces sp. KIB-H714 期刊论文
NATURAL PRODUCT RESEARCH, 2019, 卷号: 33, 期号: 2, 页码: 219-225
作者:  Dong, Miao;  Cao, Pei;  Ma, Ya-Tuan;  Luo, Jianying;  Yan, Yijun;  Li, Rong-Tao;  Huang, Sheng-Xiong
浏览  |  Adobe PDF(1106Kb)  |  收藏  |  浏览/下载：223/51  |  提交时间：2019/07/29
Actinomycin  Streptomyces  cytotoxicity  antibacterial activity  structure elucidation