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Synthesis and PDE-10 Inhibition of 3-substituted Phenylimino-indolin-2-ones 期刊论文
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2020, 卷号: 126, 页码: 34-34
作者:  Wu, Ya;  Lin, Zhiwei;  Bai, Yun;  Zhang, Yu;  Cai, Qing;  Mu, Shuzhen;  Han, Weiwei;  Hao, Xiaojiang;  Chen, Gang
收藏  |  浏览/下载：187/0  |  提交时间：2020/03/24
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：328/41  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 157, 页码: 1491-1499
作者:  Chen, Duozhi;  Zhang, Heng;  Jing, Chenxu;  He, Xiaoli;  Yang, Bijuan;  Cai, Jieyun;  Zhou, Yunfu;  Song, Xiaoming;  Li, Lin;  Hao, Xiaojiang
收藏  |  浏览/下载：371/0  |  提交时间：2018/11/12
Wnt/beta-catenin signaling agonist  Phenanthridine derivatives  Structural optimization  
The plant sesquiterpene lactone parthenolide inhibits Wnt/-catenin signaling by blocking synthesis of the transcriptional regulators TCF4/LEF1 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 14, 页码: 5335-5344
作者:  Zhu, Xiaoliang;  Yuan, Chunmao;  Tian, Chenyang;  Li, Chen;  Nie, Fen;  Song, Xiaomin;  Zeng, Rong;  Wu, Dianqing;  Hao, Xiaojiang;  Li, Lin
收藏  |  浏览/下载：419/0  |  提交时间：2018/05/08
Inhibitor  Protein Synthesis  Small Molecule  T-cell Factor (Tcf)  Wnt Signaling  
Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives. 期刊论文
Natural products and bioprospecting, 2018, 卷号: 8, 期号: 3, 页码: 189-197
作者:  Yang, Dong-Qiong;  Chen, Zhao-Rong;  Chen, Duo-Zhi;  Hao, Xiao-Jiang;  Li, Shun-Lin
收藏  |  浏览/下载：85/0  |  提交时间：2019/03/29
Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus 期刊论文
FITOTERAPIA, 2018, 卷号: 128, 页码: 204-212
作者:  Yi, Wen-fang;  Chen, Duo-zhi;  Ding, Xiao;  Li, Xiao-nian;  Li, Shun-lin;  Di, Ying-tong;  Zhang, Yu;  Hao, Xiao-jiang
收藏  |  浏览/下载：110/0  |  提交时间：2018/12/27
Autocatalytic synthesis of 3-ethyl-3-hydroxy-indole-2-ones and their neuroprotection and antitumor activities' evaluation 期刊论文
COMPTES RENDUS CHIMIE, 2018, 卷号: 21, 期号: 5, 页码: 471-474
作者:  Chen, Gang;  Lin, Jiao;  Zhang, Jie;  Wu, Ya;  Gu, Xuefan;  Hao, Xiaojiang;  Zhang, Yu
收藏  |  浏览/下载：140/0  |  提交时间：2019/03/29
Isatin  3-Ethyl-3-hydroxy-indole-2-one  Antitumor  Neuroprotection  
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 1
作者:  Yuan, Wen-Juan;  Ding, Xiao;  Wang, Zhe;  Yang, Bi-Juan;  Li, Xiao-Nian;  Zhang, Yu;  Chen, Duo-Zhi;  Li, Shun-Lin;  Chen, Quan;  Di, Ying-Tong;  Aisa, Haji Akber;  Hao, Xiao-Jiang
浏览  |  Adobe PDF(3375Kb)  |  收藏  |  浏览/下载：293/56  |  提交时间：2017/12/18
Acylphloroglucinol derivatives from the twigs and leaves of Callistemon salignus 期刊论文
TETRAHEDRON, 2017, 卷号: 73, 期号: 14, 页码: 1803-1811
作者:  Qin, Xu-Jie;  Liu, Hui;  Yu, Qian;  Yan, Huan;  Tang, Jin-Feng;  An, Lin-Kun;  Khan, Afsar;  Chen, Qi-Run;  Hao, Xiao-Jiang;  Liu, Hai-Yang
浏览  |  Adobe PDF(1199Kb)  |  收藏  |  浏览/下载：235/72  |  提交时间：2017/06/01
Callistemon Salignus  Acylphloroglucinol  Aeroterpenoid  Antimicrobial Activity  Cytotoxicity  
Chemical biology reveals CARF as a positive regulator of canonical Wnt signaling by promoting TCF/beta-catenin transcriptional activity 期刊论文
CELL DISCOVERY, 2017, 卷号: 3, 页码: 17003
作者:  He, Xiaoli;  Zhang, Wenjuan;  Yan, Chen;  Nie, Fen;  Li, Chen;  Liu, Xiaofen;  Fei, Cong;  Li, Shengdi;  Song, Xiaomin;  Jia, Yingying;  Zeng, Rong;  Wu, Dianqing;  Pan, Weijun;  Hao, Xiaojiang;  Li, Lin
浏览  |  Adobe PDF(3775Kb)  |  收藏  |  浏览/下载：155/38  |  提交时间：2017/12/18
Carf  Chemical Biology  Nc043  Small Molecule  Wnt Signaling