Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.

KIB OpenIR

	Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.
	Yang, Dong-Qiong; Chen, Zhao-Rong; Chen, Duo-Zhi; Hao, Xiao-Jiang; Li, Shun-Lin
	2018
Source Publication	Natural products and bioprospecting
ISSN	2192-2195
Volume	8 Issue:3 Pages:189-197
Abstract	Fifteen known amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Some of the compounds and lycoricidine derivatives had been screened for the activities against tobacco mosaic virus (TMV) by the conventional half-leaf method. Lycoricidine derivatives were also carried out the assay of effect on systemic infection of TMV by western-blot and RT-PCR analysis. The tested compounds showed moderate inactivation effect, whereas the lycoricidine derivatives showed good protective effect. The protective inhibitory activity of compounds L1 (N-methyl-2,3,4-trimethoxylycoricidine) (60.8%) and L3 (N-methyl-2-methoxy-3,4-acetonidelycoricidine) (62.0%) was almost similar to the positive control, Ningnanmycin (66.4%). RT-PCR and Western-blot analysis displayed that compounds L1, L3, L5 (N-allyl-2,3,4-triallyloxylycoricidine) exhibited antiviral activity, which was evidenced by reducing TMV-CP gene replication and TMV-CP protein expression. Additionally, defensive enzyme activities confirmed that compound L1 could increase the activity of PAL, POD, SOD to improve disease resistance of tobacco.
Language	英语
Document Type	期刊论文
Identifier	http://ir.kib.ac.cn/handle/151853/64810
Collection	中国科学院昆明植物研究所
Recommended Citation GB/T 7714	Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,et al. Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.[J]. Natural products and bioprospecting,2018,8(3):189-197.
APA	Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,Hao, Xiao-Jiang,&Li, Shun-Lin.(2018).Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives..Natural products and bioprospecting,8(3),189-197.
MLA	Yang, Dong-Qiong,et al."Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.".Natural products and bioprospecting 8.3(2018):189-197.

Files in This Item:
There are no files associated with this item.

If you have any objections to this item, please fill out the form below and the administrator will contact you as soon as possible.
Content:
Email：	*
Institution:
Verification Code:	Refresh

Any comments and suggestions are welcomed.
Title:	*
Content:
Email：	*
Verification Code:	Refresh

中国科学院昆明植物研究所知识管理系统