Knowledge Management System of Kunming Institute of Botany,CAS
Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives. | |
Yang, Dong-Qiong; Chen, Zhao-Rong; Chen, Duo-Zhi; Hao, Xiao-Jiang; Li, Shun-Lin | |
2018 | |
发表期刊 | Natural products and bioprospecting |
ISSN | 2192-2195 |
卷号 | 8期号:3页码:189-197 |
摘要 | Fifteen known amaryllidaceae alkaloids were isolated from the bulbs of Lycoris radiata. Some of the compounds and lycoricidine derivatives had been screened for the activities against tobacco mosaic virus (TMV) by the conventional half-leaf method. Lycoricidine derivatives were also carried out the assay of effect on systemic infection of TMV by western-blot and RT-PCR analysis. The tested compounds showed moderate inactivation effect, whereas the lycoricidine derivatives showed good protective effect. The protective inhibitory activity of compounds L1 (N-methyl-2,3,4-trimethoxylycoricidine) (60.8%) and L3 (N-methyl-2-methoxy-3,4-acetonidelycoricidine) (62.0%) was almost similar to the positive control, Ningnanmycin (66.4%). RT-PCR and Western-blot analysis displayed that compounds L1, L3, L5 (N-allyl-2,3,4-triallyloxylycoricidine) exhibited antiviral activity, which was evidenced by reducing TMV-CP gene replication and TMV-CP protein expression. Additionally, defensive enzyme activities confirmed that compound L1 could increase the activity of PAL, POD, SOD to improve disease resistance of tobacco. |
语种 | 英语 |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/64810 |
专题 | 中国科学院昆明植物研究所 |
推荐引用方式 GB/T 7714 | Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,et al. Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.[J]. Natural products and bioprospecting,2018,8(3):189-197. |
APA | Yang, Dong-Qiong,Chen, Zhao-Rong,Chen, Duo-Zhi,Hao, Xiao-Jiang,&Li, Shun-Lin.(2018).Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives..Natural products and bioprospecting,8(3),189-197. |
MLA | Yang, Dong-Qiong,et al."Anti-TMV Effects of Amaryllidaceae Alkaloids Isolated from the Bulbs ofLycoris radiata and Lycoricidine Derivatives.".Natural products and bioprospecting 8.3(2018):189-197. |
条目包含的文件 | 条目无相关文件。 |
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。
修改评论