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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：315/69  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载：327/35  |  提交时间：2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Natural products against hematological malignancies and identification of their targets 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2015, 卷号: 58, 期号: 12, 页码: 1191-1201
作者:  Xu Ying;  Liu JinBao;  Wu YingLi;  Guo QingLong;  Sun HanDong;  Chen GuoQiang
Adobe PDF(756Kb)  |  收藏  |  浏览/下载：196/32  |  提交时间：2016/05/04
Natural Products  Adenanthin  Hematological Malignancies  Target Identification  
Peroxiredoxin-1 protects estrogen receptor alpha from oxidative stress-induced suppression and is a protein biomarker of favorable prognosis in breast cancer 期刊论文
BREAST CANCER RESEARCH, 2014, 卷号: 16, 期号: 4, 页码: 8220-8224
作者:  O'Leary, Patrick C.;  Terrile, Marta;  Bajor, Malgorzata;  Gaj, Pawel;  Hennessy, Bryan T.;  Mills, Gordon B.;  Zagozdzon, Agnieszka;  O'Connor, Darran P.;  Brennan, Donal J.;  Connor, Kate;  Li, Jane;  Gonzalez-Angulo, Ana Maria;  Sun, Han-Dong;  Pu, Jian-Xin;  Ponten, Fredrik;  Uhlen, Mathias;  Jirstrom, Karin;  Nowis, Dominika A.;  Crown, John P.;  Zagozdzon, Radoslaw;  Gallagher, William M.;  Zagozdzon,R (reprint author),UCD Sch Biomol & Biomed Sci,UCD Conway Inst,Canc Biol & Therapeut Lab,Dublin 4,Ireland.;  radoslaw.zagozdzon@wum.edu.pl;  william.gallagher@ucd.ie
浏览  |  Adobe PDF(2561Kb)  |  收藏  |  浏览/下载：202/64  |  提交时间：2015/01/20
Natural-products  Roots  Secretion  Norsesquiterpenoids  Norbisabolane  Pyrimidine  
Discovery of natural estrogen receptor modulators with structure-based virtual screening 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 11, 页码: 3329-3333
作者:  Cao, Xianwen;  Jiang, Jing;  Zhang, Shoude;  Zhu, Lili;  Zou, Juan;  Diao, Yanyan;  Xiao, Weilie;  Shan, Lei;  Sun, Handong;  Zhang, Weidong;  Huang, Jin;  Li, Honglin
浏览  |  Adobe PDF(911Kb)  |  收藏  |  浏览/下载：344/100  |  提交时间：2013/07/24
Molecular Docking  Natural Product  Estrogen Receptor  Virtual Screening  
Bioactive Dibenzocyclooctadiene Lignans from the Stems of Schisandra neglecta 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 6, 页码: 1052-1057
作者:  Gao, Xue-Mei;  Wang, Rui-Rui;  Niu, De-Yun;  Meng, Chun-Yang;  Yang, Liu-Meng;  Zheng, Yong-Tang;  Yang, Guang-Yu;  Hu, Qiu-Fen;  Sun, Han-Dong;  Xiao, Wei-Lie
浏览  |  Adobe PDF(265Kb)  |  收藏  |  浏览/下载：446/206  |  提交时间：2013/10/16
Schizandra-chinensis Baill  Anti-hiv-1 Activities  Constituents  Gomisin  Sphenanthera  Kadsura  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：297/64  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Adenanthin targets peroxiredoxin I and II to induce differentiation of leukemic cells 期刊论文
NATURE CHEMICAL BIOLOGY, 2012, 卷号: 8, 期号: 5, 页码: 486-493
作者:  Liu, Chuan-Xu;  Yin, Qian-Qian;  Zhou, Hu-Chen;  Wu, Ying-Li;  Pu, Jian-Xin;  Xia, Li;  Liu, Wei;  Huang, Xin;  Jiang, Tao;  Wu, Ming-Xuan;  He, Li-Cai;  Zhao, Ya-Xue;  Wang, Xiao-Lin;  Xiao, Wei-Lie;  Chen, Hong-Zhuan;  Zhao, Qian;  Zhou, Ai-Wu;  Wang, Li-Shun;  Sun, Han-Dong;  Chen, Guo-Qiang
浏览  |  Adobe PDF(1434Kb)  |  收藏  |  浏览/下载：680/197  |  提交时间：2012/06/07
Cimicifuga Foetida  Cycloartane  Cytotoxicity  Ranunculaceae  Breast-cancer Cells  Crude Drug Shoma  Racemosa Extract  Simplex Wormsk  Cyclolanostanol Xylosides  Triterpene Glycosides  Chemical-constituents  Prostate-cancer  Aerial Parts  Black Cohosh  
Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer 期刊论文
PLOS ONE, 2011, 卷号: 6, 期号: 5, 页码: e20159
作者:  Ma, Liang;  Wen, Zhe-Sheng;  Liu, Zi;  Hu, Zheng;  Ma, Jun;  Chen, Xiao-Qin;  Liu, Yong-Qiang;  Pu, Jian-Xin;  Xiao, Wei-Lie;  Sun, Han-Dong;  Zhou, Guang-Biao
Adobe PDF(634Kb)  |  收藏  |  浏览/下载：369/121  |  提交时间：2012/03/16
Gastric-cancer  Breast-cancer  Phospho-akt  Smoking  Cells  Carcinoma  Survival  Leukemia  China  
Eriocalyxin B induces apoptosis in lymphoma cells through multiple cellular signaling pathways 期刊论文
EXPERIMENTAL HEMATOLOGY, 2010, 卷号: 38, 期号: 3, 页码: 191-201
作者:  Zhang, Yi-Wen;  Jiang, Xiao-Xing;  Chen, Qiu-Sheng;  Shi, Wen-Yu;  Wang, Lan;  Sun, Han-Dong;  Shen, Zhi-Xiang;  Chen, Zhu;  Chen, Sai-Juan;  Zhao, Wei-Li
浏览  |  Adobe PDF(1858Kb)  |  收藏  |  浏览/下载：144/50  |  提交时间：2015/08/17