Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer | |
Ma, Liang1,2; Wen, Zhe-Sheng3; Liu, Zi1; Hu, Zheng4; Ma, Jun3; Chen, Xiao-Qin3; Liu, Yong-Qiang1; Pu, Jian-Xin5![]() ![]() | |
通讯作者 | hdsun@mail.kib.ac.cn ; gbzhou@ioz.ac.cn |
2011-05-31 | |
发表期刊 | PLOS ONE
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ISSN | 1932-6203 |
卷号 | 6期号:5页码:e20159 |
摘要 | Background: Lung cancer is the leading cause of cancer deaths worldwide, with a five-year overall survival rate of only 15%. Cancerous inhibitor of PP2A (CIP2A) is a human oncoprotein inhibiting PP2A in many human malignancies. However, whether CIP2A can be a new drug target for lung cancer is largely unclear. |
关键词 | Gastric-cancer Breast-cancer Phospho-akt Smoking Cells Carcinoma Survival Leukemia China |
学科领域 | Biology |
DOI | 10.1371/journal.pone.0020159 |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000291097600025 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/3968 |
专题 | 中国科学院东亚植物多样性与生物地理学重点实验室 |
作者单位 | 1.Chinese Acad Sci, Inst Zool, State Key Lab Biomembrane & Membrane Biotechnol, Div Mol Carcinogenesis & Targeted Therapy Canc, Beijing, Peoples R China 2.Univ Sci & Technol China, Sch Life Sci, Hefei 230026, Peoples R China 3.Sun Yat Sen Univ, Canc Hosp, Guangzhou 510275, Guangdong, Peoples R China 4.Chinese Acad Sci, Guangzhou Inst Biomed & Hlth, Guangzhou, Guangdong, Peoples R China 5.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming, Peoples R China |
推荐引用方式 GB/T 7714 | Ma, Liang,Wen, Zhe-Sheng,Liu, Zi,et al. Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer[J]. PLOS ONE,2011,6(5):e20159. |
APA | Ma, Liang.,Wen, Zhe-Sheng.,Liu, Zi.,Hu, Zheng.,Ma, Jun.,...&Zhou, Guang-Biao.(2011).Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer.PLOS ONE,6(5),e20159. |
MLA | Ma, Liang,et al."Overexpression and Small Molecule-Triggered Downregulation of CIP2A in Lung Cancer".PLOS ONE 6.5(2011):e20159. |
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