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Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：315/38  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：296/66  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Synthesis, structure activity relationship and in vitro anti-influenza virus activity of novel polyphenol-pentacyclic triterpene conjugates 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 163, 页码: 560-568
作者:  Li, Haiwei;  Li, Man;  Xu, Renyang;  Wang, Shouxin;  Zhang, Yongmin;  Zhang, Lihe;  Zhou, Demin;  Xiao, Sulong
Adobe PDF(1830Kb)  |  收藏  |  浏览/下载：193/27  |  提交时间：2019/03/25
Influenza virus  Pentacyclic triterpene  Polyphenol  Entry inhibitor  Hemagglutinin  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
作者:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
Adobe PDF(2044Kb)  |  收藏  |  浏览/下载：263/29  |  提交时间：2019/03/18
Naphthomycin-derived macrolactams with two new carbon skeletons from endophytic Streptomyces 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 2, 页码: 177-182
作者:  Zhang, Zhouxin;  Cao, Pei;  Shang, Ning-Ning;  Yang, Jing;  Wang, Li;  Yan, Yijun;  Huang, Sheng-Xiong
Adobe PDF(990Kb)  |  收藏  |  浏览/下载：195/33  |  提交时间：2019/03/18
Synthesis of novel guttiferone E and xanthochymol derivatives with cytotoxicities by inducing cell apoptosis and arresting the cell cycle phase 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 162, 页码: 765-780
作者:  Lin, Xin;  Tian, Dongsong;  Fu, Yanhui;  Li, Yanan;  Huang, Liejun;  Gu, Wei;  Song, Jialei;  Li, Yanmei;  Ben-David, Yaacov;  Wen, Min;  Yuan, Chunmao;  Hao, Xiaojiang
Adobe PDF(2607Kb)  |  收藏  |  浏览/下载：285/49  |  提交时间：2019/03/18
Polycyclic polyprenylated acylphloroglucinol  Chemical transformation  Cytotoxicity  Cell apoptosis  Cell cycle arrest  
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
作者:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Adobe PDF(1823Kb)  |  收藏  |  浏览/下载：231/33  |  提交时间：2019/03/18
Cytotoxic Effects of Compounds Isolated from Ricinodendron heudelotii 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 11
作者:  Yakubu, Omolara F.;  Adebayo, Abiodun H.;  Dokunmu, Titilope M.;  Zhang, Ying-Jun;  Iweala, Emeka E. J.
Adobe PDF(1826Kb)  |  收藏  |  浏览/下载：190/36  |  提交时间：2019/03/18
anticancer  Ricinodendron heudelotii  chemoprevention  
Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 157, 页码: 103-110
作者:  Peng, XingRong;  Li, Lei;  Dong, JinRun;  Lu, ShuangYang;  Lu, Jing;  Li, XiaoNian;  Zhou, Lin;  Qiu, MingHua
Adobe PDF(830Kb)  |  收藏  |  浏览/下载：869/260  |  提交时间：2019/01/22
Ganoderma applanatum (Pers.) Pat.  Ganodermataceae  Lanostane-type triterpenoid  X-ray crystallographic analyses  Anti-liver fibrosis activity  
Cytotoxicity-Guided Isolation of Two New Phenolic Derivatives from Dryopteris fragrans (L.) Schott 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 7, 页码: 11
作者:  Zhang, Tong;  Wang, Li;  Duan, De-Hua;  Zhang, Yi-Hao;  Huang, Sheng-Xiong;  Chang, Ying
收藏  |  浏览/下载：132/0  |  提交时间：2018/11/12
cytotoxicity-guided  phenolic derivatives  Dryopteris fragrans  chemical derivatization  immuno-regulation activity