| Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum | |
Peng, XingRong1; Li, Lei1,2; Dong, JinRun1,2; Lu, ShuangYang1,2; Lu, Jing1,2; Li, XiaoNian1; Zhou, Lin1; Qiu, MingHua1
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| 2019 | |
| Source Publication | PHYTOCHEMISTRY
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| ISSN | 0031-9422 |
| Volume | 157Pages:103-110 |
| Abstract | Twelve previously undescribed lanostane-type triterpenoids, including three triterpenoids with a gamma-lactone ring, namely applanlactones A-C, four highly oxygenated lanostane triterpenoids, namely methyl applaniate A and applanoic acids B-D, as well as five C21 nortriterpenoids, applanones A-E were isolated from the fruiting bodies of Ganoderma applanatum (Pers.) Pat.. Their structures were elucidated by 1D, 2D NMR and MS spectra, as well as X-ray crystallographic analyses. Meanwhile, applanlactone A, methyl applaniate A and applanoic acid B showed inhibitory effects for the proliferation of hepatic stellate cells (HSCs) induced by transforming growth factor-beta 1 (TGF-beta 1) in vitro. |
| Keyword | Ganoderma applanatum (Pers.) Pat. Ganodermataceae Lanostane-type triterpenoid X-ray crystallographic analyses Anti-liver fibrosis activity |
| Indexed By | SCI |
| Language | 英语 |
| WOS ID | WOS:000455068200011 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/63601 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Qiu, MingHua |
| Affiliation | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
| Recommended Citation GB/T 7714 | Peng, XingRong,Li, Lei,Dong, JinRun,et al. Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum[J]. PHYTOCHEMISTRY,2019,157:103-110. |
| APA | Peng, XingRong.,Li, Lei.,Dong, JinRun.,Lu, ShuangYang.,Lu, Jing.,...&Qiu, MingHua.(2019).Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum.PHYTOCHEMISTRY,157,103-110. |
| MLA | Peng, XingRong,et al."Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum".PHYTOCHEMISTRY 157(2019):103-110. |
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