Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum | |
Peng, XingRong1; Li, Lei1,2; Dong, JinRun1,2; Lu, ShuangYang1,2; Lu, Jing1,2; Li, XiaoNian1; Zhou, Lin1; Qiu, MingHua1 | |
2019 | |
发表期刊 | PHYTOCHEMISTRY |
ISSN | 0031-9422 |
卷号 | 157页码:103-110 |
摘要 | Twelve previously undescribed lanostane-type triterpenoids, including three triterpenoids with a gamma-lactone ring, namely applanlactones A-C, four highly oxygenated lanostane triterpenoids, namely methyl applaniate A and applanoic acids B-D, as well as five C21 nortriterpenoids, applanones A-E were isolated from the fruiting bodies of Ganoderma applanatum (Pers.) Pat.. Their structures were elucidated by 1D, 2D NMR and MS spectra, as well as X-ray crystallographic analyses. Meanwhile, applanlactone A, methyl applaniate A and applanoic acid B showed inhibitory effects for the proliferation of hepatic stellate cells (HSCs) induced by transforming growth factor-beta 1 (TGF-beta 1) in vitro. |
关键词 | Ganoderma applanatum (Pers.) Pat. Ganodermataceae Lanostane-type triterpenoid X-ray crystallographic analyses Anti-liver fibrosis activity |
收录类别 | SCI |
语种 | 英语 |
WOS记录号 | WOS:000455068200011 |
引用统计 | |
文献类型 | 期刊论文 |
条目标识符 | http://ir.kib.ac.cn/handle/151853/63601 |
专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
通讯作者 | Qiu, MingHua |
作者单位 | 1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Beijing, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
推荐引用方式 GB/T 7714 | Peng, XingRong,Li, Lei,Dong, JinRun,et al. Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum[J]. PHYTOCHEMISTRY,2019,157:103-110. |
APA | Peng, XingRong.,Li, Lei.,Dong, JinRun.,Lu, ShuangYang.,Lu, Jing.,...&Qiu, MingHua.(2019).Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum.PHYTOCHEMISTRY,157,103-110. |
MLA | Peng, XingRong,et al."Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum".PHYTOCHEMISTRY 157(2019):103-110. |
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Phytochemistry.pdf(830KB) | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
Peng-2019-Lanostane-(831KB) | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 |
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