Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum
Peng, XingRong1; Li, Lei1,2; Dong, JinRun1,2; Lu, ShuangYang1,2; Lu, Jing1,2; Li, XiaoNian1; Zhou, Lin1; Qiu, MingHua1
2019
Source PublicationPHYTOCHEMISTRY
ISSN0031-9422
Volume157Pages:103-110
AbstractTwelve previously undescribed lanostane-type triterpenoids, including three triterpenoids with a gamma-lactone ring, namely applanlactones A-C, four highly oxygenated lanostane triterpenoids, namely methyl applaniate A and applanoic acids B-D, as well as five C21 nortriterpenoids, applanones A-E were isolated from the fruiting bodies of Ganoderma applanatum (Pers.) Pat.. Their structures were elucidated by 1D, 2D NMR and MS spectra, as well as X-ray crystallographic analyses. Meanwhile, applanlactone A, methyl applaniate A and applanoic acid B showed inhibitory effects for the proliferation of hepatic stellate cells (HSCs) induced by transforming growth factor-beta 1 (TGF-beta 1) in vitro.
KeywordGanoderma applanatum (Pers.) Pat. Ganodermataceae Lanostane-type triterpenoid X-ray crystallographic analyses Anti-liver fibrosis activity
Indexed BySCI
Language英语
WOS IDWOS:000455068200011
Citation statistics
Cited Times:2[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/63601
Collection植物化学与西部植物资源持续利用国家重点实验室
Corresponding AuthorQiu, MingHua
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Beijing, Peoples R China
2.Univ Chinese Acad Sci, Beijing, Peoples R China
Recommended Citation
GB/T 7714
Peng, XingRong,Li, Lei,Dong, JinRun,et al. Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum[J]. PHYTOCHEMISTRY,2019,157:103-110.
APA Peng, XingRong.,Li, Lei.,Dong, JinRun.,Lu, ShuangYang.,Lu, Jing.,...&Qiu, MingHua.(2019).Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum.PHYTOCHEMISTRY,157,103-110.
MLA Peng, XingRong,et al."Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum".PHYTOCHEMISTRY 157(2019):103-110.
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