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New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity 期刊论文
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 6, 页码: 1648-1666
作者:  Su,Lihua;  Zhang,Xintian;  Ma,Yunbao;  Geng,Changan;  Huang,Xiaoyan;  Hu,Jing;  Li,Tianze;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xuemei;  Chen,Ji-Jun
浏览  |  Adobe PDF(4074Kb)  |  收藏  |  浏览/下载：106/39  |  提交时间：2022/04/02
Guaianolide dimers  Artematrolides AeR  Artemisia atrovirens  Cytotoxicity  Cell cycle  Apoptosis  FARNESYL-PROTEIN TRANSFERASE  CELL-CYCLE ARREST  HEPATOCELLULAR-CARCINOMA  GUAIANOLIDES  LACTONES  INHIBITORS  ARTEMINOLIDE  APOPTOSIS  ARGYI  HELA  
Novel Signature Genes and Pathways Identified for Human Left Ventricle Cardiomyopathies Rise from different Etiologies 期刊论文
Journal of Biomedical Research and Reviews, 2021
作者:  Jiao Tian;  Zheng Yuan Wu;  Ying Ying He;  Shubai Liu
浏览  |  Adobe PDF(1819Kb)  |  收藏  |  浏览/下载：58/18  |  提交时间：2023/09/08
Novel Predictive Role of Serum CA19-9 Identified in Colorectal Cancer 期刊论文
International Journal of Cancer and Treatment, 2021
作者:  Zhicheng He;  Shudong Hu;  Xianghai Cai;  YingYing He;  Shubai Liu
浏览  |  Adobe PDF(1094Kb)  |  收藏  |  浏览/下载：95/30  |  提交时间：2023/09/08
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
浏览  |  Adobe PDF(8744Kb)  |  收藏  |  浏览/下载：110/41  |  提交时间：2022/04/02
Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Targeting ubiquitin conjugating enzyme UbcH5b by a triterpenoid PC3-15 from Schisandra plants sensitizes triple-negative breast cancer cells to lapatinib 期刊论文
CANCER LETTERS, 2021, 卷号: 504, 页码: 125-136
作者:  Huang,Maobo;  Zhou,Yuanfei;  Duan,Dongzhu;  Yang,Chuanyu;  Zhou,Zhongmei;  Li,Fubing;  Kong,Yanjie;  Hsieh,Yi-Ching;  Zhang,Ruihan;  Ding,Wenping;  Xiao,Weilie;  Puno,PemaTenzin;  Chen,Ceshi
浏览  |  Adobe PDF(9762Kb)  |  收藏  |  浏览/下载：92/21  |  提交时间：2022/04/02
HECTD3  UbcH5b  Ubiquitination  Autophagy  Schisandraceae triterpenoid  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
浏览  |  Adobe PDF(523Kb)  |  收藏  |  浏览/下载：81/20  |  提交时间：2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Musarin, a novel protein with tyrosine kinase inhibitory activity from Trametes versicolor, accepted inhibits colorectal cancer stem cell growth 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 144, 页码: 112339
作者:  He,YingYing;  Liu,Shubai;  Newburg,David S.
浏览  |  Adobe PDF(4251Kb)  |  收藏  |  浏览/下载：116/21  |  提交时间：2022/04/02
Trametes versicolor  Cancer stem cell  Tyrosine kinase inhibitor  EGFR  Colorectal cancer  FACTOR RECEPTOR  POLYSACCHAROPEPTIDE  RESISTANCE  TARGET  EGFR  TOOL  PSP  DNA  
Discovery and synthesis of rocaglaol derivatives inducing apoptosis in HCT116 cells via suppression of MAPK signaling pathway 期刊论文
FITOTERAPIA, 2021, 卷号: 151, 页码: 104876
作者:  Yang,Hao-Jie;  Li,Ya-Nan;  Yan,Chen;  Yang,Jue;  Zeng,Yan-Rong;  Yi,Ping;  Li,Yan-Mei;  Hao,Xiao-Jiang;  Yuan,Chun-Mao
浏览  |  Adobe PDF(2804Kb)  |  收藏  |  浏览/下载：89/25  |  提交时间：2022/04/02
Dysoxylum gotadhora  Rocaglaol derivatives  HCT116  Cytotoxic activity  MAPK pathway  FLAVAGLINES  
CtBP1/2 differentially regulate genomic stability and DNA repair pathway in high-grade serous ovarian cancer cell 期刊论文
ONCOGENESIS, 2021, 卷号: 10, 期号: 7, 页码: 49
作者:  He,YingYing;  He,Zhicheng;  Lin,Jian;  Chen,Cheng;  Chen,Yuanzhi;  Liu,Shubai
浏览  |  Adobe PDF(3008Kb)  |  收藏  |  浏览/下载：84/15  |  提交时间：2022/04/02
BINDING-PROTEIN CTBP  TRANSCRIPTIONAL COREPRESSOR  NEGATIVE MODULATION  PROMOTES APOPTOSIS  GENE-EXPRESSION  DAMAGE RESPONSE  PK  OVEREXPRESSION  PHOSPHOPROTEIN  TRANSFORMATION  
USP47 maintains the stemness of colorectal cancer cells and is inhibited by parthenolide 期刊论文
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2021, 卷号: 562, 页码: 21-28
作者:  Zhang,Shaohua;  Ju,Xiaoman;  Yang,Qihong;  Zhu,Yiying;  Fan,Dongmei;  Su,Guifeng;  Kong,Lingmei;  Li,Yan
浏览  |  Adobe PDF(2615Kb)  |  收藏  |  浏览/下载：154/37  |  提交时间：2022/04/02
USP47  Cancer stem cell  Colorectal cancer  Parthenolide  Deubiquitinase  SESQUITERPENE LACTONE PARTHENOLIDE  DEUBIQUITINASES  STABILIZATION  LEUKEMIA