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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
Authors:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
Favorite  |  View/Download:75/0  |  Submit date:2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Isopenicins A-C: Two Types of Antitumor Meroterpenoids from the Plant Endophytic Fungus Penicillium sp. sh18 期刊论文
ORGANIC LETTERS, 2019, 卷号: 21, 期号: 3, 页码: 771-775
Authors:  Tang, Jian-Wei;  Kong, Ling-Mei;  Zu, Wen-Yu;  Hu, Kun;  Li, Xiao-Nian;  Yan, Bing-Chao;  Wang, Wei-Guang;  Sun, Han-Dong;  Li, Yan;  Puno, Pema-Tenzin
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Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
Authors:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
Favorite  |  View/Download:74/0  |  Submit date:2019/03/18
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
Authors:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
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adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Synthesis of Novel ent-Kaurane-Type Diterpenoid Derivatives Effective for Highly Aggressive Tumor Cells 期刊论文
MOLECULES, 2018, 卷号: 23, 期号: 12, 页码: 9
Authors:  Hu, Yu;  Li, Xiao-Nian;  Ma, Ze-Jin;  Puno, Pema-Tenzin;  Zhao, Yong;  Zhao, Yan;  Xiao, Ye-Zhi;  Zhang, Wei;  Liu, Jing-Ping
Favorite  |  View/Download:3/0  |  Submit date:2019/03/18
ent-kaurane-type diterpenoid derivatives  antitumor  synthesis  
Structurally diverse diterpenoids from Isodon pharicus 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 15, 页码: 2379-2389
Authors:  Hu, Zheng-Xi;  Xu, Hou-Chao;  Hu, Kun;  Liu, Miao;  Li, Xiao-Nian;  Li, Xing-Ren;  Du, Xue;  Zhang, Yong-Hui;  Puno, Pema-Tenzin;  Sun, Han-Dong
Favorite  |  View/Download:220/0  |  Submit date:2018/09/17
Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis 期刊论文
MOLECULAR OMICS, 2018, 卷号: 14, 期号: 3, 页码: 156-169
Authors:  Zhou, Xunian;  Cao, Cyanne Ye;  Wan, Angel Tsz-Yau;  Yue, Grace Gar-Lee;  Kwok, Frankie Hin-Fai;  Fung, Kwok-Pui;  Sun, Handong;  Lau, Clara Bik-San;  Puno, Pema-Tenzin;  Tsui, Stephen Kwok-Wing
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Schinortriterpenoids with Identical Configuration but Distinct ECD Spectra Generated by Nondegenerate Exciton Coupling 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 6, 页码: 1500-1504
Authors:  Shi, Yi-Ming;  Hu, Kun;  Pescitelli, Gennaro;  Liu, Miao;  Li, Xiao-Nian;  Du, Xue;  Xiao, Wei-Lie;  Sun, Han-Dong;  Puno, Pema-Tenzin
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Rabdocoestin B exhibits antitumor activity by inducing G2/M phase arrest and apoptosis in esophageal squamous cell carcinoma 期刊论文
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2018, 卷号: 81, 期号: 3, 页码: 469-481
Authors:  Wang, Jingnan;  Zhang, Zhirong;  Che, Yun;  Yuan, Zuyang;  Lu, Zhiliang;  Li, Yuan;  Wan, Jun;  Sun, Handong;  Chen, Zhaoli;  Pu, Jianxin;  He, Jie
Favorite  |  View/Download:222/0  |  Submit date:2018/05/08
Rabdocoestin b  G2/m Phase Arrest  Apoptosis  Cytotoxicity  Esophageal Squamous Cell Carcinoma  
Elaborating the Role of Natural Products on the Regulation of Autophagy and their Potentials in Breast Cancer Therapy 期刊论文
CURRENT CANCER DRUG TARGETS, 2018, 卷号: 18, 期号: 3, 页码: 239-255
Authors:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Tsui, Stephen Kwok-Wing;  Pu, Jianxin;  Fung, Kwok-Pui;  Lau, Clara Bik-San
Favorite  |  View/Download:23/0  |  Submit date:2018/05/08
Autophagy  Natural Products  Breast Cancer  Cancer Therapy  Mtor Signaling  Apoptosis