| Total Synthesis of (-)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone | |
Long, Yang1,2,3; Ding, Yiming2,3,4; Wu, Hai2,3,4; Qu, Chunlei2,3,4; Liang, Hong2,3,4; Zhang, Min2,3,4; Zhao, Xiaoli2,3,4; Long, Xianwen2,3,4; Wang, Shu1; Puno, Pema-Tenzin2,3 ; Deng, Jun2,3
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| Corresponding Author | Deng, Jun(dengjun@mail.kib.ac.cn) |
| 2019-11-08 | |
| Source Publication | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
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| ISSN | 1433-7851 |
| Pages | 6 |
| Abstract | The first copper-catalyzed intermolecular [5+2] homodimerization of hydroxy p-quinone is presented, furnishing bicyclo[3.2.1]octadienone core structures in typically good yields and excellent diastereoselectivities. Applying this synthetic approach enables a concise nine-step total synthesis of (-)-perezoperezone from commercially available 3,5-dimethoxytoluene. |
| Keyword | 5+2 cycloaddition dimerization natural products perezoperezone total synthesis |
| DOI | 10.1002/anie.201911978 |
| Indexed By | SCI ; SCI |
| Language | 英语 |
| WOS ID | WOS:000495083600001 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/70980 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Corresponding Author | Deng, Jun |
| Affiliation | 1.Sichuan Univ, West China Sch Pharm, Dept Med Nat Prod, Chengdu 610041, Sichuan, Peoples R China 2.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, 132 Lanhei Rd, Kunming, Yunnan, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, Yunnan Key Lab Nat Med Chem, 132 Lanhei Rd, Kunming, Yunnan, Peoples R China 4.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| Recommended Citation GB/T 7714 | Long, Yang,Ding, Yiming,Wu, Hai,et al. Total Synthesis of (-)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2019:6. |
| APA | Long, Yang.,Ding, Yiming.,Wu, Hai.,Qu, Chunlei.,Liang, Hong.,...&Deng, Jun.(2019).Total Synthesis of (-)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,6. |
| MLA | Long, Yang,et al."Total Synthesis of (-)-Perezoperezone through an Intermolecular [5+2] Homodimerization of Hydroxy p-Quinone".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019):6. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| long2019.pdf（2181KB） | 期刊论文 | 出版稿 | 开放获取 | CC BY-NC-SA | View Application Full Text | |
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