Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea

doi:10.1039/c9qo00281b

	Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea
	Xu, Hou-Chao 1,2,3; Hu, Kun1,2 ; Shi, Xiao-Huo 1,2; Tang, Jian-Wei 1,2; Li, Xiao-Nian 1,2; Sun, Han-Dong1,2 ; Puno, Pema-Tenzin1,2
通讯作者	Puno, Pema-Tenzin(punopematenzin@mail.kib.ac.cn)
	2019-05-21
发表期刊	ORGANIC CHEMISTRY FRONTIERS
ISSN	2052-4129
卷号	6 期号:10 页码:1619-1626
摘要	Neokadcoccitane A (1), an unprecedented 14(13. 12): 28(14. 8)-diabeo-3,4-secolanostane triterpenoid possessing an aromatic ring D and an unusual Me-21 orientation, along with two novel 14(13. 12)-abeo-3,4- seco-norlanostane triterpenoids featuring three-and one-carbon degradation, respectively (2 and 3), were isolated from the roots of Kadsura coccinea. The absolute configuration of 1 was determined by the synergistic use of NMR computation, quantitative interproton distance analysis, and TDDFT ECD calculation, while that of 2 was established using X-ray diffraction. 1 was found to exhibit moderate anti-platelet aggregation activity.
DOI	10.1039/c9qo00281b
收录类别	SCI
语种	英语
WOS记录号	WOS:000468001500011
引用统计
文献类型	期刊论文
条目标识符	http://ir.kib.ac.cn/handle/151853/67498
专题	植物化学与西部植物资源持续利用国家重点实验室
通讯作者	Puno, Pema-Tenzin
作者单位	1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China 2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
推荐引用方式 GB/T 7714	Xu, Hou-Chao,Hu, Kun,Shi, Xiao-Huo,et al. Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea[J]. ORGANIC CHEMISTRY FRONTIERS,2019,6(10):1619-1626.
APA	Xu, Hou-Chao.,Hu, Kun.,Shi, Xiao-Huo.,Tang, Jian-Wei.,Li, Xiao-Nian.,...&Puno, Pema-Tenzin.(2019).Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea.ORGANIC CHEMISTRY FRONTIERS,6(10),1619-1626.
MLA	Xu, Hou-Chao,et al."Synergistic use of NMR computation and quantitative interproton distance analysis in the structural determination of neokadcoccitane A, a rearranged triterpenoid featuring an aromatic ring D from Kadsura coccinea".ORGANIC CHEMISTRY FRONTIERS 6.10(2019):1619-1626.

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