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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
浏览  |  Adobe PDF(17974Kb)  |  收藏  |  浏览/下载：206/20  |  提交时间：2024/07/17
Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Snail-inspired AFG/GelMA hydrogel accelerates diabetic wound healing via inflammatory cytokines suppression and macrophage polarization 期刊论文
BIOMATERIALS, 2023, 卷号: 299, 页码: 122141
作者:  Zhou,Zhipeng;  Deng,Tuo;  Tao,Maixian;  Lin,Lisha;  Sun,Luyun;  Song,Xuemei;  Gao,Dongxiu;  Li,Jixing;  Wang,Zhongjuan;  Wang,Xingzi;  Li,Jinpeng;  Jiang,Zexiu;  Luo,Lan;  Yang,Lian;  Wu,Mingyi
浏览  |  Adobe PDF(24778Kb)  |  收藏  |  浏览/下载：202/41  |  提交时间：2024/07/22
Diabetic wound healing  Biomimetic hydrogels  Glycosaminoglycan  Inflammation suppression  Macrophage polarization  FOOT ULCERS  HUMAN SKIN  ACTIVATION  MANAGEMENT  RECEPTORS  DRESSINGS  EFFICACY  SAFETY  
Discovery and biological evaluation of a new type of dual inhibitors of indoleamine 2,3-dioxygenase 1 and tryptophan 2,3-dioxygenase from ethnomedicinal plant Dactylicapnos scandens 期刊论文
PHYTOCHEMISTRY, 2023, 卷号: 214, 页码: 113794
作者:  Bao,Mei-Fen;  Yang,Xin-Ni;  Wu,Jing;  Liu,Jiang-Xin;  Cai,Xiang-Hai
浏览  |  Adobe PDF(3069Kb)  |  收藏  |  浏览/下载：165/37  |  提交时间：2024/07/25
Dactylicapnos scandens (D. don) hutch.  Isoquinoline alkaloids  Aporphine-type alkaloids  Dactycapnine a  IDO1/TDO dual inhibitor  APORPHINE ALKALOIDS  N-OXIDE  INFLAMMATION  PATHWAY  THALIPORPHINE  COMPLEXES  CANCER  ROOTS  
The extracts of Lobaria pindarensis, an edible lichen from Himalayas, suppress inflammatory response and fibrillation of amyloid β-protein in cultured microglial cells: Active depsidones, norstictic acid and stictic acid, are responsible for the functions 期刊论文
JOURNAL OF FUNCTIONAL FOODS, 2023, 卷号: 107, 页码: 105607
作者:  Yang,Mei-Xia;  Cheng,Edwin Hok-Chi;  Ospondpant,Dusadee;  Tung,Ka-Ki;  Wang,Li-Song;  Lin,Sheng-Ying;  Lai,Queenie Wing-Sze;  Wu,Qi-Yun;  Xia,Ying-Jie;  Leung,Ka-Wing;  Duan,Ran;  Dong,Tina Ting-Xia;  Tsim,Karl Wah-Keung
浏览  |  Adobe PDF(4569Kb)  |  收藏  |  浏览/下载：146/16  |  提交时间：2024/07/25
Alzheimer's disease  Inflammation  Fibrillar A beta  Lichen  Lobaria pindarensis  Depsidone  IN-SILICO  IDENTIFICATION  INHIBITORS  
Parabacteroides distasonis ameliorates hepatic fibrosis potentially via modulating intestinal bile acid metabolism and hepatocyte pyroptosis in male mice 期刊论文
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 1829
作者:  Zhao,Qi;  Dai,Man-Yun;  Huang,Ruo-Yue;  Duan,Jing-Yi;  Zhang,Ting;  Bao,Wei-Min;  Zhang,Jing-Yi;  Gui,Shao-Qiang;  Xia,Shu-Min;  Dai,Cong-Ting;  Tang,Ying-Mei;  Gonzalez,Frank J. J.;  Li,Fei
浏览  |  Adobe PDF(5393Kb)  |  收藏  |  浏览/下载：236/41  |  提交时间：2024/05/09
FATTY LIVER-DISEASE  INDUCED CHOLESTASIS  STELLATE CELLS  PROBIOTICS  PROTECTS  INFLAMMATION  APOPTOSIS  OBESITY  AXIS  
光交联的多糖AFG-GelMA水凝胶愈合糖尿病伤口的药效学研究 学位论文
: 中国科学院大学, 2022
作者:  宋雪梅
Adobe PDF(5776Kb)  |  收藏  |  浏览/下载：219/0  |  提交时间：2024/05/14
糖尿病伤口愈合，蜗牛糖胺聚糖，水凝胶，慢性炎症，巨噬细胞  Diabetic wound healing, Snail glycosaminoglycan, Hydrogels, Chronic inflammation, Macrophages  
天然多糖AFG水凝胶的制备及其在皮肤创面愈合中的应用 学位论文
: 中国科学院大学, 2022
作者:  蒋泽秀
Adobe PDF(4884Kb)  |  收藏  |  浏览/下载：126/0  |  提交时间：2024/05/14
蜗牛糖胺聚糖，明胶，水凝胶，炎症，伤口愈合  Snail Glycosaminoglycan, Gelatin, Hydrogel, Inflammation, Wound Healing  
Apigenin exerts chemopreventive effects on lung injury induced by SiO2 nanoparticles through the activation of Nrf2 期刊论文
JOURNAL OF NATURAL MEDICINES, 2022, 卷号: 76, 期号: 1, 页码: 119-131
作者:  Wang,Yajun;  Chang,Wenhui;  Li,Xuezheng;  Jiang,Zhe;  Zhou,Di;  Feng,Yuan;  Li,Bingxin;  Chen,Gang;  Li,Ning
收藏  |  浏览/下载：433/0  |  提交时间：2022/04/02
APG  Lung injury  Nm SiO2  Nrf2  Chemoprevention  OCCUPATIONAL SILICA EXPOSURE  OXIDATIVE STRESS  PARTICULATE MATTER  INDUCED APOPTOSIS  CELL-LINE  CANCER  PROTECTS  NEUROPROTECTION  INFLAMMATION  TOXICITY  
Association of sirtuins (SIRT1-7) with lung and intestinal diseases 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2022, 卷号: 477, 期号: 11, 页码: 2539-2552
作者:  Chen, Yuhan;  Zhou, Di;  Feng, Yuan;  Li, Bingxin;  Cui, Yong;  Chen, Gang;  Li, Ning
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：215/47  |  提交时间：2024/04/30
Sirtuins  Lung-intestinal axis  Inflammation  Tumors  MicroRNAs  ENDOPLASMIC-RETICULUM STRESS  EPITHELIAL-MESENCHYMAL TRANSITION  CANCER CELLS  ULCERATIVE-COLITIS  COLORECTAL-CANCER  DOWN-REGULATION  PROLIFERATION  SUPPRESSES  ACTIVATION  APOPTOSIS  
Anti-Inflammatory Effects of Camellia fascicularis Polyphenols via Attenuation of NF-kappa B and MAPK Pathways in LPS-Induced THP-1 Macrophages 期刊论文
JOURNAL OF INFLAMMATION RESEARCH, 2022, 卷号: 15, 页码: 851-864
作者:  Gao, Miaozi;  Peng, Xiaowei;  Tang, Junrong;  Deng, Jia;  Wang, Fang;  Zhang, Yingjun;  Zhao, Ping;  Kan, Huan;  Liu, Yun
浏览  |  Adobe PDF(9145Kb)  |  收藏  |  浏览/下载：214/48  |  提交时间：2024/04/30
Camellia fascicularis  polyphenols  anti-inflammatory activity  NF-kappa B  MAPK  LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION  OXIDATIVE STRESS  CELLS  SUPPRESSION  ANTIOXIDANT  ACTIVATION  NRF2/HO-1  RESPONSES  PROTEIN  CANCER