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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis 期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:  Li,Sujuan;  Wang,Weili;  Lin,Lisha;  Yang,Lian;  Cai,Ying;  Yang,Xingzhi;  Zhang,Taocui;  Xiao,Chuang;  Yan,Hui;  Gao,Na;  Zhao,Jinhua
Adobe PDF(2610Kb)  |  收藏  |  浏览/下载：4/1  |  提交时间：2024/05/09
oligosaccharide  platelet activation  receptor  protease-activated  thrombin thrombosis  ANTIPLATELET THERAPIES  ALLOSTERIC LINKAGE  TISSUE FACTOR  PROTEASE  VORAPAXAR  MECHANISM  REVEALS  SITE  
Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea Cucumber Acaudina molpadioides Stimulate Neurite Outgrowth 期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 653
作者:  Wang, Weili;  Mao, Hui;  Li, Sujuan;  Zhang, Longlong;  Yang, Lian;  Yin, Ronghua;  Zhao, Jinhua
Adobe PDF(5142Kb)  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/04/30
fucosylated chondroitin sulfate  sea cucumber  disaccharide branch  oligosaccharide  neurite outgrowth  stimulation  HIPPOCAMPAL-NEURONS  PROMOTING ACTIVITY  GLYCOSAMINOGLYCAN  DISACCHARIDE  INHIBITOR  
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants 期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
作者:  Lin,Lisha;  Li,Sujuan;  Gao,Na;  Wang,Weili;  Zhang,Taocui;  Yang,Lian;  Yang,Xingzhi;  Luo,Dan;  Ji,Xu;  Zhao,Jinhua
浏览  |  Adobe PDF(2854Kb)  |  收藏  |  浏览/下载：75/10  |  提交时间：2022/04/02
fucosylated glycosaminoglycan  anticoagulant  platelet aggregation  contact activation  hypotension  pulmonary embolism  CHONDROITIN SULFATE  CONTACT SYSTEM  COMPLEMENT  COAGULATION  ACTIVATION  ACCUMULATION  INVOLVEMENT  DERIVATIVES  KALLIKREIN  THROMBOSIS  
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2021, 卷号: 32, 期号: 7, 页码: 975-983
作者:  Lin,Lisha;  Yang,Lian;  Chen,Jun;  Zhou,Lutan;  Li,Sujuan;  Gao,Na;  Zhao,Jinhua
浏览  |  Adobe PDF(3733Kb)  |  收藏  |  浏览/下载：58/16  |  提交时间：2022/04/02
Aggregation  fucosylated glycosaminoglycan  human platelets  secretion  alpha(IIb beta 3)  DEPOLYMERIZED HOLOTHURIAN GLYCOSAMINOGLYCAN  INTRINSIC TENASE COMPLEX  INTEGRIN ALPHA(IIB)BETA(3)  ACTIVATION  AGGLUTINATION  RECEPTOR  ADP  INHIBITION  GENERATION  MECHANISM  
Oligosaccharides from fucosylated glycosaminoglycan prevent breast cancer metastasis in mice by inhibiting heparanase activity and angiogenesis 期刊论文
PHARMACOLOGICAL RESEARCH, 2021, 卷号: 166, 页码: 105527
作者:  Zhou,Lutan;  Yin,Ronghua;  Gao,Na;  Sun,Huifang;  Chen,Dingyuan;  Cai,Ying;  Ren,Lin;  Yang,Lian;  Zuo,Zhili;  Zhang,Hongbin;  Zhao,Jinhua
浏览  |  Adobe PDF(8336Kb)  |  收藏  |  浏览/下载：86/11  |  提交时间：2022/04/02
Oligosaccharides  Heparanase  Angiogenesis  Metastasis  FIBROBLAST-GROWTH-FACTOR  TUMOR-GROWTH  SULFATE PROTEOGLYCANS  MAMMALIAN HEPARANASE  COMBINATION  MECHANISMS  DISCOVERY  BINDING  TARGET  PI-88  
A regular fucan sulfate from Stichopus herrmanni and its peroxide depolymerization: Structure and anticoagulant activity 期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 256, 页码: 117513
作者:  Li,Xiaomei;  Li,Shanni;  Liu,Jie;  Lin,Lisha;  Sun,Huifang;  Yang,Wenjiao;  Cai,Ying;  Gao,Na;  Zhou,Lutan;  Qin,Hongbo;  Yin,Ronghua;  Zhao,Jinhua
浏览  |  Adobe PDF(3183Kb)  |  收藏  |  浏览/下载：89/16  |  提交时间：2022/04/02
fucan sulfate  peroxide depolymerization  oligosaccharides  anti-thrombin activity  FUCOSYLATED CHONDROITIN SULFATE  FREE-RADICAL DEPOLYMERIZATION  PHYSICOCHEMICAL CHARACTERISTICS  REPEATING UNIT  BODY-WALL  SEA  FUCOIDAN  GLYCOSAMINOGLYCAN  POLYSACCHARIDES  HEPARIN  
Effects of Native Fucosylated Glycosaminoglycan, Its Depolymerized Derivatives on Intrinsic Factor Xase, Coagulation, Thrombosis, and Hemorrhagic Risk 期刊论文
THROMBOSIS AND HAEMOSTASIS, 2020
作者:  Zhou, Lutan;  Gao, Na;  Sun, Huifang;  Xiao, Chuang;  Yang, Lian;  Lin, Lisha;  Yin, Ronghua;  Li, Zi;  Zhang, Hongbin;  Ji, Xu;  Zhao, Jinhua
浏览  |  Adobe PDF(1210Kb)  |  收藏  |  浏览/下载：217/53  |  提交时间：2021/01/05
A new fucosylated glycosaminoglycan containing disaccharide branches from Acaudina molpadioides: Unusual structure and anti-intrinsic tenase activity 期刊论文
CARBOHYDRATE POLYMERS, 2020
作者:  Mao, Hui;  Cai, Ying;  Li, Shanni;  Sun, Huifang;  Lin, Lisha;  Pan, Ying;  Yang, Wenjiao;  He, Zhicheng;  Chen, Ru;  Zhou, Lutan;  Wang, Weili;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(2623Kb)  |  收藏  |  浏览/下载：95/19  |  提交时间：2021/01/05
High-molecular-weight fucosylated glycosaminoglycan induces human platelet aggregation depending on alpha(IIb)beta(3) and platelet secretion 期刊论文
PLATELETS, 2020
作者:  Lin, Lisha;  Yang, Lian;  Chen, Jun;  Zhou, Lutan;  Li, Sujuan;  Gao, Na;  Zhao, Jinhua
浏览  |  Adobe PDF(4004Kb)  |  收藏  |  浏览/下载：76/12  |  提交时间：2021/01/05
NMR characterization and anticoagulant activity of the oligosaccharides from the fucosylated glycosaminoglycan isolated from Holothuria coluber 期刊论文
CARBOHYDRATE POLYMERS, 2020
作者:  Yang, Wenjiao;  Chen, Dingyuan;  He, Zhicheng;  Zhou, Lutan;  Cai, Ying;  Mao, Hui;  Gao, Na;  Zuo, Zhili;  Yin, Ronghua;  Zhao, Jinhua
浏览  |  Adobe PDF(2127Kb)  |  收藏  |  浏览/下载：169/70  |  提交时间：2021/01/05