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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(9057Kb)  |  收藏  |  浏览/下载:192/41  |  提交时间:2020/03/26
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
Adobe PDF(3136Kb)  |  收藏  |  浏览/下载:164/56  |  提交时间:2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
Adobe PDF(4316Kb)  |  收藏  |  浏览/下载:219/39  |  提交时间:2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 713-717
作者:  Yan, Huan;  Qin, Xu-Jie;  Li, Xu-Hong;  Yu, Qian;  Ni, Wei;  He, Li;  Liu, Hai-Yang
Adobe PDF(1127Kb)  |  收藏  |  浏览/下载:243/22  |  提交时间:2019/04/15
Chloranthus japonicus  Lindenane sesquiterpenoid dimer  Japonicones A-C  ECD calculation  
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
作者:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
收藏  |  浏览/下载:220/0  |  提交时间:2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase  
In Vitro Human Dihydroorotate Dehydrogenase Inhibitory, Anti-inflammatory and Cytotoxic Activities of Alkaloids from the Seeds of Nigella glandulifera 期刊论文
PLANTA MEDICA, 2018, 卷号: 84, 期号: 14, 页码: 1013-1021
作者:  Gao, Jun-Bo;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Zhu, Li-Li;  Pu, De-Bing;  Li, Xiao-Li;  Li, Hong-Lin;  Xu, Min;  Xiao, Wei-Lie
收藏  |  浏览/下载:99/0  |  提交时间:2018/10/22
dolabellane-type diterpene alkaloids  Ranunculaceae  Nigella glandulifera  human dihydroorotate dehydrogenase  lipopolysaccharide  nitric oxide production  cytotoxic activity  
Total synthesis of (-)-akaol A via a conformational constraint strategy 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2018, 卷号: 5, 期号: 12, 页码: 1886-1889
作者:  Liu, Hao-Miao;  Chen, Dong;  Xu, Wen-Dan;  Dang, Li-Zhi;  Qin, Hong-Bo
收藏  |  浏览/下载:188/0  |  提交时间:2018/07/16
Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 1, 页码: 46-48
作者:  Li, Ming-Ming;  Xia, Fan;  Li, Cheng-Ji;  Xu, Gang;  Qin, Hong-Bo
Adobe PDF(299Kb)  |  收藏  |  浏览/下载:173/41  |  提交时间:2018/05/08
Tanshinones  Heterocyclic Compounds  Cytotoxicity  
Protostane-Type Triterpenoids from Alisma orientale 期刊论文
CHEMISTRY & BIODIVERSITY, 2017, 卷号: 14, 期号: 12, 页码: e1700452
作者:  Li, Hong-Mei;  Chen, Xue-Jiao;  Luo, Dan;  Fan, Min;  Zhang, Zhi-Jun;  Peng, Li-Yan;  Wu, Xing-De;  Li, Rong-Tao;  Ji, Xu;  Zhao, Qin-Shi
收藏  |  浏览/下载:234/0  |  提交时间:2018/05/08
Alisma Orientale  Alismatis Rhizoma  Alismataceae  Protostane Triterpenoids  Vasorelaxant Activity  
Selected Mutations Revealed Intermediates and Key Precursors in the Biosynthesis of Polyketide-Terpenoid Hybrid Sesquiterpenyl Epoxy-cyclohexenoids 期刊论文
ORGANIC LETTERS, 2017, 卷号: 19, 期号: 14, 页码: 3923-3926
作者:  Teng, Lin-Lin;  Song, Tian-Yang;  Xu, Zi-Fei;  Liu, Xiao;  Dai, Rong;  Chen, Yong-Hong;  Li, Sheng-Hong;  Zhang, Ke-Qin;  Niu, Xue-Mei
Adobe PDF(1132Kb)  |  收藏  |  浏览/下载:278/103  |  提交时间:2017/10/23
Fungus Arthrobotrys-oligospora  Morphological Regulatory Arthrosporols  Metabolite Production  Antibiotics  Disruption  Mechanisms  Patulin