Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives
Li, Ming-Ming1,2,4; Xia, Fan1,2,3,4; Li, Cheng-Ji1,2,3; Xu, Gang1,2; Qin, Hong-Bo1,2
2018-01-03
Source PublicationTETRAHEDRON LETTERS
ISSN0040-4039
Volume59Issue:1Pages:46-48
AbstractTanshinones were used as starting material to synthesize a small library of nitrogen heterocyclic derivatives featured with oxazole, imidazole, and pyrazine ring between C-11/C-12 by simple methods. Except for salviamine A and isosalviamine A, 22 new derivatives were synthesized. Their structures were confirmed by spectroscopic analysis. Moreover, 11 derivatives exhibited moderate cytotoxic activities against five human cancer lines in vitro. (C) 2017 Elsevier Ltd. All rights reserved.
KeywordTanshinones Heterocyclic Compounds Cytotoxicity
DOI10.1016/j.tetlet.2017.11.046
Language英语
WOS IDWOS:000423006200010
Citation statistics
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/60591
Collection植物化学与西部植物资源持续利用国家重点实验室
Affiliation1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
2.Yunnan Key Lab Nat Med Chem, Kunming 650201, Yunnan, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Yunnan Baiyao Grp Corp Ltd, Kunming 650032, Yunnan, Peoples R China
Recommended Citation
GB/T 7714
Li, Ming-Ming,Xia, Fan,Li, Cheng-Ji,et al. Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives[J]. TETRAHEDRON LETTERS,2018,59(1):46-48.
APA Li, Ming-Ming,Xia, Fan,Li, Cheng-Ji,Xu, Gang,&Qin, Hong-Bo.(2018).Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives.TETRAHEDRON LETTERS,59(1),46-48.
MLA Li, Ming-Ming,et al."Design, synthesis and cytotoxicity of nitrogen-containing tanshinone derivatives".TETRAHEDRON LETTERS 59.1(2018):46-48.
Files in This Item: Download All
File Name/Size DocType Version Access License
li2018.pdf(299KB)期刊论文作者接受稿开放获取CC BY-NC-SAView Download
Related Services
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Google Scholar
Similar articles in Google Scholar
[Li, Ming-Ming]'s Articles
[Xia, Fan]'s Articles
[Li, Cheng-Ji]'s Articles
Baidu academic
Similar articles in Baidu academic
[Li, Ming-Ming]'s Articles
[Xia, Fan]'s Articles
[Li, Cheng-Ji]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Li, Ming-Ming]'s Articles
[Xia, Fan]'s Articles
[Li, Cheng-Ji]'s Articles
Terms of Use
No data!
Social Bookmark/Share
File name: li2018.pdf
Format: Adobe PDF
All comments (0)
No comment.
 

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.