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Metabolic Activation of Elemicin Leads to the Inhibition of Stearoyl-CoA Desaturase 1 期刊论文
CHEMICAL RESEARCH IN TOXICOLOGY, 2019, 卷号: 32, 期号: 10, 页码: 1965-1976
作者:  Yang, Xiao-Nan;  Wang, Yi-Kun;  Zhu, Xu;  Xiao, Xue-Rong;  Dai, Man-Yun;  Zhang, Ting;  Qu, Yan;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(9057Kb)  |  收藏  |  浏览/下载：192/41  |  提交时间：2020/03/26
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：224/69  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Zhu, Xu;  Xiao, Xue-Rong;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3136Kb)  |  收藏  |  浏览/下载：165/56  |  提交时间：2019/09/10
elemicin  l'-hydroxyelemicin  metabolic activation  cytotoxicity  
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity 期刊论文
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:  Zhu, Xu;  Wang, Yi-Kun;  Yang, Xiao-Nan;  Xiao, Xue-Rong;  Zhang, Ting;  Yang, Xiu-Wei;  Qin, Hong-Bo;  Li, Fei
浏览  |  Adobe PDF(4316Kb)  |  收藏  |  浏览/下载：219/39  |  提交时间：2019/05/24
myristicin  1 '-hydroxymyristicin  metabolic activation  metabolomics  
Japonicones A-C: Three lindenane sesquiterpenoid dimers with a 12-membered ring core from Chloranthus japonicus 期刊论文
TETRAHEDRON LETTERS, 2019, 卷号: 60, 期号: 10, 页码: 713-717
作者:  Yan, Huan;  Qin, Xu-Jie;  Li, Xu-Hong;  Yu, Qian;  Ni, Wei;  He, Li;  Liu, Hai-Yang
浏览  |  Adobe PDF(1127Kb)  |  收藏  |  浏览/下载：243/22  |  提交时间：2019/04/15
Chloranthus japonicus  Lindenane sesquiterpenoid dimer  Japonicones A-C  ECD calculation  
Premnafulvol A: A Diterpenoid with a 6/5/7/3-Fused Tetracyclic Core and Its Biosynthetically Related Analogues from Premna fulva 期刊论文
ORGANIC LETTERS, 2018, 卷号: 20, 期号: 19, 页码: 6314-6317
作者:  Pu, De-Bing;  Du, Bao-Wen;  Chen, Wen;  Gao, Jun-Bo;  Hu, Kun;  Shi, Nan;  Li, Yi-Ming;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Wang, Fei;  Xiao, Wei-Lie
收藏  |  浏览/下载：179/0  |  提交时间：2018/11/12
LC-MS guided isolation of gracilistones A and B, a pair of diastereomeric sesquiterpenoids with an unusual tetrahydrofuran-fused tricyclic skeleton from Acanthopanax gracilistylus and their potential anti-inflammatory activities 期刊论文
FITOTERAPIA, 2018, 卷号: 130, 页码: 265-271
作者:  Xu, Hong-Bo;  Yang, Tong-Hua;  Xie, Pei;  Tang, Zhi-Shu;  Song, Xiao;  Xu, Huai-Li;  Li, Yan-Hong;  Zhang, Dong-Bo;  Liu, Yan-Ru;  Liang, Yan-Ni;  Zhang, Yu;  Liu, Shi-Jun;  Wei, Si-Min;  Sun, Chen;  Liu, Hong-Bo;  Deng, Chong;  Wang, Wei
收藏  |  浏览/下载：220/0  |  提交时间：2018/12/03
Acanthopanax gracilistylus  Eudesmane-type sesquiterpenoid  LC-MS  Anti-inflammation  Anti-oxidant  Xanthine oxidase  
In Vitro Human Dihydroorotate Dehydrogenase Inhibitory, Anti-inflammatory and Cytotoxic Activities of Alkaloids from the Seeds of Nigella glandulifera 期刊论文
PLANTA MEDICA, 2018, 卷号: 84, 期号: 14, 页码: 1013-1021
作者:  Gao, Jun-Bo;  Zhang, Xing-Jie;  Zhang, Rui-Han;  Zhu, Li-Li;  Pu, De-Bing;  Li, Xiao-Li;  Li, Hong-Lin;  Xu, Min;  Xiao, Wei-Lie
收藏  |  浏览/下载：99/0  |  提交时间：2018/10/22
dolabellane-type diterpene alkaloids  Ranunculaceae  Nigella glandulifera  human dihydroorotate dehydrogenase  lipopolysaccharide  nitric oxide production  cytotoxic activity  
Antimicrobial indole alkaloids with adductive C-9 aromatic unit from Gelsemium elegans 期刊论文
TETRAHEDRON LETTERS, 2018, 卷号: 59, 期号: 21, 页码: 2066-2070
作者:  Wei, Xin;  Yang, Jing;  Ma, Hong-Xia;  Ding, Cai-Feng;  Yu, Hao-Fei;  Zhao, Yun-Li;  Liu, Ya-Ping;  Khan, Afsar;  Wang, Yi-Fen;  Yang, Zi-Feng;  Huang, Wan-Yi;  Wang, Xin-Hua;  Luo, Xiao-Dong
浏览  |  Adobe PDF(1063Kb)  |  收藏  |  浏览/下载：236/63  |  提交时间：2018/07/02
Gelsemium Elegans  Indole Alkaloids  Antimicrobial Activities  
Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi 期刊论文
PHYTOCHEMISTRY, 2018, 卷号: 148, 页码: 57-62
作者:  Zheng, Guowei;  Luo, Shihong;  Li, Shifei;  Hua, Juan;  Li, Weiqi;  Li, Shenghong
收藏  |  浏览/下载：229/0  |  提交时间：2018/05/08
Ageratina Adenophora  Asteraceae  Roots  Specialized Metabolites  Antifungal Activity