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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：329/74  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Construction of Tetracyclic 3-Spirooxindole through Cross-Dehydrogenation of Pyridinium: Applications in Facile Synthesis of (+/-)-Corynoxine and (+/-)-Corynoxine B 期刊论文
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 卷号: 136, 期号: 52, 页码: 17962-17965
作者:  Xu, Jun;  Shao, Li-Dong;  Li, Dashan;  Deng, Xu;  Liu, Yu-Chen;  Zhao, Qin-Shi;  Xia, Chengfeng
Adobe PDF(696Kb)  |  收藏  |  浏览/下载：504/83  |  提交时间：2015/06/17
Synthesis and cytotoxic activity of novel 1-((indol-3-yl)methyl)-1H-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 21, 页码: 4926-4930
作者:  Xu, Xiao-Liang;  Wang, Jia;  Yu, Chun-Lei;  Chen, Wen;  Li, Ying-Chao;  Li, Yan;  Zhang, Hong-Bin;  Yang, Xiao-Dong;  Li,Y (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650204,Peoples R China.;  liyanb@mail.kib.ac.cn;  zhanghbyd@gmail.com;  xdyang@ynu.edu.cn
Adobe PDF(670Kb)  |  收藏  |  浏览/下载：376/89  |  提交时间：2014/11/25
Indole  Imidazolium Salts  Structure-activity Relationships  Cell Apoptosis  
Cyclohexane-Fused Octahydroquinolizine Alkaloids from Myrioneuron faberi with Activity against Hepatitis C Virus 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2014, 卷号: 79, 期号: 17, 页码: 7945-7950
作者:  Cao, Ming-Ming;  Zhang, Yu;  Li, Xiao-Hui;  Peng, Zong-Gen;  Jiang, Jian-Dong;  Gu, Yu-Cheng;  Di, Ying-Tong;  Li, Xiao-Nian;  Chen, Duo-Zhi;  Xia, Cheng-Feng;  He, Hong-Ping;  Li, Shun-Lin;  Hao, Xiao-Jiang;  haoxj@mail.kib.ac.cn
Adobe PDF(364Kb)  |  收藏  |  浏览/下载：290/76  |  提交时间：2014/11/25
Biomimetic Synthesis  Nutans  Nitraramine  Skeleton  Therapy  
Peganumine A, a beta-Carboline Dimer with a New Octacyclic Scaffold from Peganum harmala 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 15, 页码: 4028-4031
作者:  Wang, Kai-Bo;  Di, Ying-Tong;  Bao, Yu;  Yuan, Chun-Mao;  Chen, Gang;  Li, Da-Hong;  Bai, Jiao;  He, Hong-Ping;  Hao, Xiao-Jiang;  Pei, Yue-Hu;  Jing, Yong-Kui;  Li, Zhan-Lin;  Hua, Hui-Ming;  Li, ZL (reprint author), Shenyang Pharmaceut Univ, Minist Educ, Key Lab Struct Based Drug Design & Discovery, Shenyang 110016, Liaoning, Peoples R China.;  lzl1030@hotmail.com;  huimhua@163.com
Adobe PDF(295Kb)  |  收藏  |  浏览/下载：306/91  |  提交时间：2014/10/11
Light-emitting-diodes  Alkaloid Extract  Potent  L.  Derivatives  Efficiency  Toxicity  Harmine  Cascade  Growth  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：294/43  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Sesquiterpenoids and Diterpenes from Chamaecyparis obtusa var. breviramea f. crippsii 期刊论文
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, 2014, 卷号: 69, 期号: 3, 页码: 362-368
作者:  Xu, Jian;  Zeng, Guang-Zhi;  Liu, Yi-Mei;  Chen, Ke-Li;  Sun, Zhang-Hua;  Zhang, Yu-Mei;  Tan, Ning-Hua
Adobe PDF(184Kb)  |  收藏  |  浏览/下载：248/54  |  提交时间：2014/06/23
Chamaecyparis Obtusa Var. Breviramea F. Crippsii  Sesquiterpenoids  Diterpenes  Cytotoxicity  
Limonoids from Aphanamixis polystachya and Their Antifeedant Activity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 3, 页码: 472-482
作者:  Cai, Jie-Yun;  Chen, Duo-Zhi;  Luo, Shi-Hong;  Kong, Ning-Chuan;  Zhang, Yu;  Di, Ying-Tong;  Zhang, Qiang;  Hua, Juan;  Jing, Shu-Xi;  Li, Shun-Lin;  Li, Sheng-Hong;  Hao, Xiao-Jiang;  He, Hong-Ping
Adobe PDF(477Kb)  |  收藏  |  浏览/下载：400/121  |  提交时间：2014/05/16
Biological-activities  Cipadessa-baccifera  Meliaceae  Tetranortriterpenoids  Sesquiterpenes  Triterpenoids  Prieurianin  Derivatives  Chemistry  Mangrove  
Anti-HIV active daphnane diterpenoids from Trigonostemon thyrsoideum 期刊论文
PHYTOCHEMISTRY, 2013, 卷号: 96, 页码: 360-369
作者:  Cheng, Yuan-Yuan;  Chen, Huan;  He, Hong-Ping;  Zhang, Yu;  Li, Shi-Fei;  Tang, Gui-Hua;  Guo, Ling-Li;  Yang, Wei;  Zhu, Feng;  Zheng, Yong-Tang;  Li, Shun-Lin;  Hao, Xiao-Jiang
Adobe PDF(973Kb)  |  收藏  |  浏览/下载：263/72  |  提交时间：2015/05/13
Trigonostemon Thyrsoideum  Euphorbiaceae  Daphnane Diterpenoids  Trigothysoids A-p  Anti-hiv-1  
Evaluation of anti-HCV activity and SAR study of (+)-lycoricidine through targeting of host heat-stress cognate 70 (Hsc70) 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 9, 页码: 2679-2682
作者:  Chen, Duo-Zhi;  Jiang, Jian-Dong;  Zhang, Ke-Qing;  He, Hong-Ping;  Di, Ying-Tong;  Zhang, Yu;  Cai, Jie-Yun;  Wang, Lei;  Li, Shun-Lin;  Yi, Ping;  Peng, Zong-Gen;  Hao, Xiao-Jiang
Adobe PDF(555Kb)  |  收藏  |  浏览/下载：506/105  |  提交时间：2013/06/08
(+)-lycoricidine  Heat-stress Cognate 70 (Hsc70)  Down-regulators  Structure-activity Relationship (Sar)  Anti-hcv Activity