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Celastrol as an intestinal FXR inhibitor triggers tripolide-induced intestinal bleeding: Underlying mechanism of gastrointestinal injury induced by Tripterygium wilfordii 期刊论文
PHYTOMEDICINE, 2023, 卷号: 121, 页码: 155054
作者:  Dai,Manyun;  Peng,Wan;  Lin,Lisha;  Wu,Zhanxuan;  Zhang,Ting;  Zhao,Qi;  Cheng,Yan;  Lin,Qiuxia;  Zhang,Binbin;  Liu,Aiming;  Rao,Qianru;  Huang,Jianfeng;  Zhao,Jinhua;  Gonzalez,Frank J.;  Li,Fei
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Intestinal bleeding  Triptolide  Celastrol  Intestinal FXR  Tripterygium wilfordii  FARNESOID-X-RECEPTOR  BACTERIAL TRANSLOCATION  ACTIVATION  INFLAMMATION  DYSFUNCTION  TRIPTOLIDE  MICROBIOTA  PREVENTS  OBESITY  MICE  
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Guaiane-type Sesquiterpenoid Dimers from Artemisia zhongdianensis and Antihepatoma Carcinoma Activity via the p38MAPK Pathway 期刊论文
CHINESE JOURNAL OF CHEMISTRY, 2023, 卷号: 41, 期号: 19, 页码: 2453-2468
作者:  Dong,Wei;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Li,Tian-Ze;  Wang,Yong-Cui;  He,Xiao-Feng;  Geng,Chang-An;  Zhang,Xue-Mei;  Chen,Ji-Jun
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Artemzhongdianolides B1-B17  Artemisia zhongdianensis  Guaiane-type sesquiterpenoid dimers  Antihepatoma activity  p38MAPK pathway  Cancer  NMR spectroscopy  X-ray diffraction  ARREST  CELLS  JNK  
Design and synthesis of guaianolide-germacranolide heterodimers as novel anticancer agents against hepatocellular carcinoma 期刊论文
DRUG DEVELOPMENT RESEARCH, 2023
作者:  Yan,Jia-Xin;  Li,Qi-Hao;  Li,Tian-Ze;  Huang,Zhi-Yan;  Ma,Yun-Bao;  Chen,Ji-Jun
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antihepatoma effects  guaianolide-germacranolide heterodimers  PDGFRA  DERIVATIVES  
Bioactive triterpenoids from the traditional Chinese medicine Swertia mileensis 期刊论文
PHYTOCHEMISTRY LETTERS, 2023, 卷号: 55, 页码: 1-5
作者:  Yuan,Xin;  Yan,Qin;  Hu,Hong;  He,Xiao-Ping;  Wang,Li-Xia;  Liu,Yan-Chun;  Liu,Yan;  Guo,Kai;  Li,Sheng-Hong
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Swertia mileensis  Gentianaceae  Triterpenoids  Anti-inflammatory activity  Cytotoxicity  
Artemeriopolides A-D, two types of sesquiterpenoid dimers with rare carbon skeletons from Artemisia eriopoda and their antihepatoma cytotoxicity 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2023, 卷号: 10, 期号: 11, 页码: 2635-2641
作者:  He,Xiao-Feng;  Li,Qi-Hao;  Li,Tian-Ze;  Ma,Yun-Bao;  Dong,Wei;  Yang,Ke-Xin;  Geng,Chang-An;  Zhang,Hao-Wei;  Wang,Yuan;  Chen,Ji-Jun
浏览  |  Adobe PDF(1676Kb)  |  收藏  |  浏览/下载：2/1  |  提交时间：2024/07/22
Artemdubinoids A-N: novel sesquiterpenoids with antihepatoma cytotoxicity from Artemisia dubia 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2023, 卷号: 21, 期号: 12, 页码: 902-915
作者:  Gao,Zhen;  Li,Tianze;  Ma,Yunbao;  Huang,Xiaoyan;  Geng,Changan;  Zhang,Xuemei;  Chen,Jijun
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Artemdubinoids A-N  Artemisia dubia  Sesquiterpenoids  Antihepatoma activity  
Design, synthesis, and biological evaluation of artemyrianolide H derivatives as potential antihepatoma agents 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 137, 页码: 106617
作者:  Li,Tian-Ze;  Yang,Xiao-Tong;  Ma,Wen-Jing;  Ma,Yun-Bao;  Li,Feng-Jiao;  Wang,Yong-Cui;  Chen,Ji-Jun
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Artemyrianolide H  Germacranolide derivatives  Antihepatoma activity  Apoptosis  DIMERS  
Design and synthesis of ludartin derivatives as potential anticancer agents against hepatocellular carcinoma 期刊论文
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 7, 页码: 1224-1239
作者:  Sun, Jin-Jin;  Wang, Jin-Ping;  Li, Tian-Ze;  Ma, Yun-Bao;  Xue, Dong;  Chen, Ji-Jun
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Ludartin derivatives  Antihepatoma activity  HepG2 cells  Huh7 cells  SESQUITERPENE LACTONES  CHEMICAL-CONSTITUENTS  GUAIANOLIDES  ANTITUMOR  ANALOGS  
Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2020
作者:  Zhou, Han;  Peng, Xingrong;  Hou, Tao;  Zhao, Nan;  Qiu, Minghua;  Zhang, Xiuli;  Liang, Xinmiao
浏览  |  Adobe PDF(3740Kb)  |  收藏  |  浏览/下载：141/42  |  提交时间：2021/01/05