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The pharmacokinetics of anthocyanins and their metabolites in humans 期刊论文
出版物, 3111, 期号: 0, 页码: 1-37
作者:  R M de Ferrars;  C Czank;  Q Zhang;  N P Botting;  P A Kroon;  A Cassidy;  C D Kay
Adobe PDF(1873Kb)  |  收藏  |  浏览/下载：158/1  |  提交时间：2017/07/24
Anthocyanins  Metabolites  Hippuric Acid  Ferulic Acid  Vanillic Acid  
Identification and Characterization of ShSPI, a Kazal-Type Elastase Inhibitor from the Venom of Scolopendra Hainanum 期刊论文
TOXINS, 2019, 卷号: 11, 期号: 12, 页码: 13
作者:  Luan, Ning;  Zhao, Qiyu;  Duan, Zilei;  Ji, Mengyao;  Xing, Meichen;  Zhu, Tengyu;  Mwangi, James;  Rong, Mingqiang;  Liu, Jiangxin;  Lai, Ren
浏览  |  Adobe PDF(2415Kb)  |  收藏  |  浏览/下载：201/35  |  提交时间：2020/03/18
centipede  kazal-type inhibitor  human neutrophils elastase  ShSPI  
Design, synthesis and biological evaluation of novel copper-chelating acetylcholinesterase inhibitors with pyridine and N-benzylpiperidine fragments 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 93, 页码: 13
作者:  Zhou, Yeheng;  Sun, Wei;  Peng, Jiale;  Yan, Hui;  Zhang, Li;  Liu, Xingyong;  Zuo, Zhili
浏览  |  Adobe PDF(4739Kb)  |  收藏  |  浏览/下载：206/31  |  提交时间：2020/03/18
Acetylcholinesterase  Drug design  N-acylhydrazone  Dementia  Copper-chelating  N-Benzylpiperidine  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：227/29  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Impaired clearance of sunitinib leads to metabolic disorders and hepatotoxicity 期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2019, 卷号: 176, 期号: 13, 页码: 2162-2178
作者:  Zhao, Qi;  Zhang, Ting;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Wang, Yan;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(3915Kb)  |  收藏  |  浏览/下载：244/41  |  提交时间：2019/07/29
A metabolomic perspective of pazopanib-induced acute hepatotoxicity in mice 期刊论文
XENOBIOTICA, 2019, 卷号: 49, 期号: 6, 页码: 655-670
作者:  Wang, Yi-Kun;  Yang, Xiao-Nan;  Liang, Wei-Qing;  Xiao, Yao;  Zhao, Qi;  Xiao, Xue-Rong;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1101Kb)  |  收藏  |  浏览/下载：269/110  |  提交时间：2019/07/29
Pazopanib  hepatotoxicity  metabolomics  oxidative stress  ultra-performance liquid chromatography-electrospray ion source-quadrupole  time-of-flight mass spectrometer (UPLC-ESI-QTOFMS)  
Alkaloid chemodiversity in Mandragora spp. is associated with loss-of-functionality of MoH6H, a hyoscyamine 6 beta-hydroxylase gene 期刊论文
PLANT SCIENCE, 2019, 卷号: 283, 页码: 301-310
作者:  Schlesinger, Daniel;  Rikanati, Rachel Davidovich;  Volis, Sergei;  Faigenboim, Adi;  Vendramin, Vera;  Cattonaro, Federica;  Hooper, Matthew;  Oren, Elad;  Taylor, Mark;  Sitrit, Yaron;  Inbar, Moshe;  Lewinsohn, Efraim
浏览  |  Adobe PDF(5585Kb)  |  收藏  |  浏览/下载：200/40  |  提交时间：2019/07/29
Tropane alkaloids  Anisodamine  Hyoscyamine  Scopolamine  Solanaceae  Cleaved-amplified-polymorphic-sequence (CAPS) analyses  2-Oxoglutarate-dependent dioxygenases  
Three new compounds with nitric oxide inhibitory activity from Tirpitzia sinensis, an ethnomedicinal plant from Southwest China 期刊论文
BMC CHEMISTRY, 2019, 卷号: 13, 页码: 12
作者:  Gu, Ronghui;  Wang, Yuehu;  Wu, Shibiao;  Wang, Yeling;  Li, Ping;  Xu, Li;  Zhou, Yue;  Chen, Ze'e;  Kennelly, Edward J.;  Long, Chunlin
浏览  |  Adobe PDF(1972Kb)  |  收藏  |  浏览/下载：164/25  |  提交时间：2019/07/29
Tirpitzia sinensis  Linaceae  Lignans  Inflammatory  NO inhibition  Pharmacological targets  Pharmacophore  In silico  
Precise Structure and Anticoagulant Activity of Fucosylated Glycosaminoglycan from Apostichopus japonicus: Analysis of Its Depolymerized Fragments 期刊论文
MARINE DRUGS, 2019, 卷号: 17, 期号: 4, 页码: 13
作者:  Guan, Ruowei;  Peng, Yuan;  Zhou, Lutan;  Zheng, Wenqi;  Liu, Xixi;  Wang, Pin;  Yuan, Qingxia;  Gao, Na;  Zhao, Longyan;  Zhao, Jinhua
浏览  |  Adobe PDF(2313Kb)  |  收藏  |  浏览/下载：177/6  |  提交时间：2019/06/24
Apostichopus japonicus  fucosylated glycosaminoglycan  oligosaccharide  unambiguous structure  anti-Fxase  
Statistically correlating NMR spectra and LC-MS data to facilitate the identification of individual metabolites in metabolomics mixtures 期刊论文
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 2019, 卷号: 411, 期号: 7, 页码: 1301-1309
作者:  Li, Xing;  Luo, Huan;  Huang, Tao;  Xu, Li;  Shi, Xiaohuo;  Hu, Kaifeng
浏览  |  Adobe PDF(1588Kb)  |  收藏  |  浏览/下载：201/48  |  提交时间：2019/07/29
Deconvolution  LC-MS  NMR  Statistical correlation  Structure identification