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Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors 期刊论文
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:  Sajesh, Babu, V;  On, Ngoc H.;  Omar, Refaat;  Alrushaid, Samaa;  Kopec, Brian M.;  Wang, Wei-Guang;  Sun, Han-Dong;  Lillico, Ryan;  Lakowski, Ted M.;  Siahaan, Teruna J.;  Davies, Neal M.;  Puno, Pema-Tenzin;  Vanan, Magimairajan Issai;  Miller, Donald W.
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blood-brain barrier (BBB)  drug delivery  transient modulation  HAV6 cadherin peptide  adenanthin  magnetic resonance imaging (MRI)  medulloblastoma  
Pharmacokinetics and safety evaluation in healthy Chinese volunteers of alkaloids from leaf of Alstonia scholaris: A multiple doses phase I clinical trial 期刊论文
PHYTOMEDICINE, 2019, 卷号: 61, 页码: 13
作者:  Li, Rui;  Zi, Ming-Jie;  Gou, Zhong-Ping;  Zhao, Yun-Li;  Zhang, Wan-Tong;  Lu, Fang;  Cao, Wei-Yi;  Zhao, Ying-Pan;  Li, Qing-Na;  Zhao, Yang;  Wang, Shu-Ge;  Gao, Hong-Yang;  Sun, Ming-Yue;  Luo, Xiao-Dong;  Xiong, Zhi-Li;  Gao, Rui
浏览  |  Adobe PDF(3744Kb)  |  收藏  |  浏览/下载：253/73  |  提交时间：2020/03/17
Capsule of alkaloids from leaf of A. scholaris (CALAS)  Pharmacokinetics  Safety evaluation  Drug re-excitation research  
Bioinformatics analysis of differentially expressed genes in hepatocellular carcinoma cells exposed to Swertiamarin 期刊论文
JOURNAL OF CANCER, 2019, 卷号: 10, 期号: 26, 页码: 6526-6534
作者:  Tang, Haoran;  Ke, Yang;  Ren, Zongfang;  Lei, Xuefen;  Xiao, Shufeng;  Bao, Tianhao;  Shi, Zhitian;  Zou, Renchao;  Wu, Tiangen;  Zhou, Jian;  Geng, Chang-An;  Wang, Lin;  Chen, Jijun
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swertiamarin  microarray  HepG2 cells  hepatocellular cancer  Jun  Stat3  
Borapetoside E, a Clerodane Diterpenoid Extracted from Tinospora crispa, Improves Hyperglycemia and Hyperlipidemia in High-Fat-Diet-Induced Type 2 Diabetes Mice 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 8, 页码: 2319-2327
作者:  Xu, Yuhui;  Niu, Yanfen;  Gao, Yuan;  Wang, Fang;  Qin, Wanying;  Lu, Yanting;  Hu, Jing;  Peng, Li;  Liu, Jikai;  Xiong, Wenyong
浏览  |  Adobe PDF(4940Kb)  |  收藏  |  浏览/下载：375/61  |  提交时间：2017/10/23
Insulin-resistance  Tuberculata Beumee  Metabolic Syndrome  Srebp  Liver  Cholesterol  Constituents  Homeostasis  Inhibition  Receptors  
Modulation of glucose metabolism by a natural compound from Chloranthus japonicus via activation of AMP-activated protein kinase 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 778
作者:  Hu, Rongkuan;  Yan, Huan;  Fei, Xiaoyan;  Liu, Haiyang;  Wu, Jiarui
Adobe PDF(2283Kb)  |  收藏  |  浏览/下载：265/56  |  提交时间：2017/06/01
In vitro assessment of the glucose-lowering effects of berberrubine-9-O-beta-D-glucuronide, an active metabolite of berberrubine 期刊论文
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 3, 页码: 351-361
作者:  Yang, Na;  Sun, Run-Bin;  Chen, Xing-Long;  Zhen, Le;  Ge, Chun;  Zhao, Yu-Qing;  He, Jun;  Geng, Jian-Liang;  Guo, Jia-Hua;  Yu, Xiao-Yi;  Fei, Fei;  Feng, Si-Qi;  Zhu, Xuan-Xuan;  Wang, Hong-Bo;  Fu, Feng-Hua;  Aa, Ji-Ye;  Wang, Guang-Ji
Adobe PDF(4661Kb)  |  收藏  |  浏览/下载：271/90  |  提交时间：2017/05/19
Hyperglycemia  Glucose-lowering Effect  Berberine  Berberrubine  Glucuronide  Alpha-glycosidase  Hfd-induced Hyperglycemia Model Of C57bl/6 Mice  Human Normal Liver Cell Line L-o2  Pharmacokinetics  
Influence of P-glycoprotein on the disposition of fexofenadine and its enantiomers 期刊论文
JOURNAL OF PHARMACY AND PHARMACOLOGY, 2017, 卷号: 69, 期号: 3, 页码: 274-284
作者:  Li, Fei;  Howard, Karyn D.;  Myers, Michael J.
Adobe PDF(641Kb)  |  收藏  |  浏览/下载：139/53  |  提交时间：2017/05/19
Abcb1-1 Delta  Collies  Enantiomer  Fexofenadine  Fluorescence  
Cognitive-enhancing effects of beta-sitosterol in vanadium-induced neurotoxicity in mice 期刊论文
JOURNAL OF NEUROCHEMISTRY, 2017, 卷号: 142, 页码: 238-238
作者:  Adebiyi,O.;  Olayemi,F.;  Olopade,J.;  Ning-Hua,T.
Adobe PDF(878Kb)  |  收藏  |  浏览/下载：168/76  |  提交时间：2017/10/23
Potential effects of climate change on geographic distribution of the Tertiary relict tree species Davidia involucrata in China 期刊论文
SCIENTIFIC REPORTS, 2017, 卷号: 7, 页码: 43822
作者:  Tang,Cindy Q.;  Dong,Yi-Fei;  Herrando-Moraira,Sonia;  Matsui,Tetsuya;  Ohashi,Haruka;  He,Long-Yuan;  Nakao,Katsuhiro;  Tanaka,Nobuyuki;  Tomita,Mizuki;  Li,Xiao-Shuang;  Yan,Hai-Zhong;  Peng,Ming-Chun;  Hu,Jun;  Yang,Ruo-Han;  Li,Wang-Jun;  Yan,Kai;  Hou,Xiuli;  Zhang,Zhi-Ying;  Lopez-Pujol,Jordi
Adobe PDF(5229Kb)  |  收藏  |  浏览/下载：220/39  |  提交时间：2017/10/23
Last Glacial Maximum  Western North-america  Quaternary Climate  Extinction Risk  Change Threats  Europe  Phylogeography  Populations  Responses  Habitat  
Bavachinin, as a novel natural pan-PPAR agonist, exhibits unique synergistic effects with synthetic PPAR-gamma and PPAR-alpha agonists on carbohydrate and lipid metabolism in db/db and diet-induced obese mice 期刊论文
DIABETOLOGIA, 2016, 卷号: 59, 期号: 6, 页码: 1276-1286
作者:  Feng, Li;  Luo, Huan;  Xu, Zhijian;  Yang, Zhuo;  Du, Guoxin;  Zhang, Yu;  Yu, Lijing;  Hu, Kaifeng;  Zhu, Weiliang;  Tong, Qingchun;  Chen, Kaixian;  Guo, Fujiang;  Huang, Cheng;  Li, Yiming
Adobe PDF(841Kb)  |  收藏  |  浏览/下载：253/99  |  提交时间：2016/08/22
Alternative Binding Site  Bavachinin  Canonical Ligand-binding Pocket  Carbohydrate Metabolism  Lipid Metabolism  Pan-ppar Agonist  Synergistic Effects