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Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2015, 卷号: 90, 页码: 775-787
作者:  Liu, Chin-Yu;  Cheng, Yung-Yi;  Chang, Ling-Chu;  Huang, Li-Jiau;  Chou, Li-Chen;  Huang, Chi-Hung;  Tsai, Meng-Tung;  Liao, Chih-Chang;  Hsu, Mei-Hua;  Lin, Hui-Yi;  Wu, Tian-Shung;  Wen, Yen-Fang;  Zhao, Yu;  Kuo, Sheng-Chu;  Lee, Kuo-Hsiung;  Kuo,SC (reprint author),China Med Univ,Grad Inst Pharmaceut Chem,91 Hsueh Shih Rd,Taichung 40402,Taiwan.;  sckuo@mail.cmu.edu.tw;  khlee@unc.edu
浏览  |  Adobe PDF(1696Kb)  |  收藏  |  浏览/下载：355/84  |  提交时间：2015/06/29
2-arylnaphthyridin-4-ones  Antitumor Agents  Phosphate Prodrug  
Cochlearols A and B, Polycyclic Meroterpenoids from the Fungus Ganoderma cochlear That Have Renoprotective Activities 期刊论文
ORGANIC LETTERS, 2014, 卷号: 16, 期号: 23, 页码: 6064-6067
作者:  Dou, Man;  Di, Lei;  Zhou, Li-Li;  Yan, Yong-Ming;  Wang, Xin-Long;  Zhou, Feng-Jiao;  Yang, Zhu-Liang;  Li, Rong-Tao;  Hou, Fan-Fan;  Cheng, Yong-Xian;  Li,RT (reprint author),Kunming Univ Sci Technol,Fac Life Sci & Technol,Kunming 650500,Peoples R China.;  lrt512@163.com;  ffhouguangzhou@163.com;  yxcheng@mail.kib.ac.cn
浏览  |  Adobe PDF(299Kb)  |  收藏  |  浏览/下载：388/65  |  提交时间：2015/01/20
Thermal Time Requirements  Environmental-factors  Emergence  Steppe  Light  Ecology  Desert  China  Plant  Germinability  Alpine Steppe  Seed Germination  Cardinal Temperature  Thermal Time  Stipa Species  Tibetan Plateau  
New alkaloids sinomacutines A-E, and cephalonine-2-O-beta-D-glucopyranoside from rhizomes of Sinomenium acutum 期刊论文
TETRAHEDRON, 2014, 卷号: 70, 期号: 46, 页码: 8893-8899
作者:  Li, Yan-Hong;  Li, Hong-Mei;  Li, Yan;  He, Juan;  Deng, Xu;  Peng, Li-Yan;  Gao, Ling-Huan;  Zhao, Qin-Shi;  Li, Rong-Tao;  Wu, Xing-De;  Li,RT (reprint author),Kunming Univ Sci & Technol,Fac Life Sci & Technol,Kunming 650500,Yunnan,Peoples R China.;  rongtaolikm@gmail.com;  wuxingde@mail.kib.ac.cn
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Sinomenium Acutum  Bistetrahydroisoquinoline Alkaloid  Acid Hydrolysis  Cytotoxicity  Anti-inflammatory Activity  
Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 卷号: 24, 期号: 8, 页码: 1884-1888
作者:  Yan, Chen;  Huang, Li;  Liu, Hong-Chun;  Chen, Duo-Zhi;  Liu, Hai-Yang;  Li, Xiao-Hui;  Zhang, Yu;  Geng, Mei-Yu;  Chen, Quan;  Hao, Xiao-Jiang
Adobe PDF(1562Kb)  |  收藏  |  浏览/下载：314/51  |  提交时间：2014/06/23
Spiramine Derivative  Bax(-/-)/bak(-/-) Cells  Alpha  Apoptosis  Beta-unsaturated Ketone  Cytotoxicity  
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
作者:  Zhu, Jinmei;  Wu, Chun-Feng;  Li, Xiaobing;  Wu, Gui-Sheng;  Xie, Shan;  Hu, Qian-Nan;  Deng, Zixin;  Zhu, Michael X.;  Luo, Huai-Rong;  Hong, Xuechuan
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Alzheimer's Disease  Acetylcholinesterase  Butyrylcholinesterase  Molecular Modeling  2-aminobenzimidazole  
Anthraquinone derivatives from Rumex plants and endophytic Aspergillus fumigatus and their effects on diabetic nephropathy 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 卷号: 23, 期号: 13, 页码: 3905-3909
作者:  Yang, Yang;  Yan, Yong-Ming;  Wei, Wei;  Luo, Jie;  Zhang, Lan-Sheng;  Zhou, Xiao-Jiang;  Wang, Peng-Cheng;  Yang, Yong-Xun;  Cheng, Yong-Xian
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Anthraquinone  Oxanthrone C-glycoside  Diabetic Nephropathy  Rumex  Endophytic Aspergillus Fumigatus  
Bioactive ent-Kaurane Diterpenoids from Isodon rosthornii 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2013, 卷号: 76, 期号: 7, 页码: 1267-1277
作者:  Zhan, Rui;  Li, Xiao-Nian;  Du, Xue;  Wang, Wei-Guang;  Dong, Ke;  Su, Jia;  Li, Yan;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(448Kb)  |  收藏  |  浏览/下载：491/238  |  提交时间：2013/10/16
Lasiocarpus Hayata Kudo  Nf-kappa-b  Leukemic-cells  Terpenoids  Rubescens  Differentiation  Cytotoxicity  Constituents  Pharicin  
Dual-Functional abeo-Taxane Derivatives Destabilizing Microtubule Equilibrium and Inhibiting NF-kappa B Activation 期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 56, 期号: 11, 页码: 4749-4757
作者:  Zhao, Yu;  Su, Jia;  Goto, Masuo;  Morris-Natschke, Susan L.;  Li, Yan;  Zhao, Qin-Shi;  Yao, Zhu-Jun;  Lee, Kuo-Hsiung
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Natural-products  Biological-activity  Cancer-therapy  Paclitaxel  Taxol  Resistance  Drugs  Chemotherapy  Parthenolide  Brevifoliol  
Unusual Spirodecane Sesquiterpenes and a Fumagillol Analogue from Cordyceps ophioglossoides 期刊论文
HELVETICA CHIMICA ACTA, 2013, 卷号: 96, 期号: 1, 页码: 76-84
作者:  Sun, Yisheng;  Zhao, Zhao;  Feng, Qiangsheng;  Xu, Qinqin;  Lu, Longxian;  Liu, Ji-Kai;  Zhang, Ling;  Wu, Bin;  Li, Yong-Quan
浏览  |  Adobe PDF(211Kb)  |  收藏  |  浏览/下载：347/96  |  提交时间：2013/03/18
Cordyceps Ophioglossoides  CordyA?-?cepols a?-?A?-?c  Cordycol  Cytotoxic Activity  Fungi  
Design, synthesis, and molecular hybrids of caudatin and cinnamic acids as novel anti-hepatitis B virus agents 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2012, 卷号: 54, 页码: 352-365
作者:  Wang, Li-Jun;  Geng, Chang-An;  Ma, Yun-Bao;  Luo, Jie;  Huang, Xiao-Yan;  Chen, Hao;  Zhou, Ning-Jia;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(719Kb)  |  收藏  |  浏览/下载：444/143  |  提交时间：2012/11/30
Synthesis  Molecular Hybrids  Caudatin Derivatives  Anti-hepatitis b Virus  Unique Mechanisms