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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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植物化学与西部植物... [10]
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罗怀容 [9]
吴桂生 [6]
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Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels
期刊论文
JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 60, 期号: 11, 页码: 4680-4692
Authors:
Qu, Chunrong
;
Ding, Mingmin
;
Zhu, Yingmin
;
Lu, Yungang
;
Du, Juan
;
Miller, Melissa
;
Tian, Jinbin
;
Zhu, Jinmei
;
Xui, Jian
;
Wen, Meng
;
Er-Bu, Aga
;
Wan, Jule
;
Xiao, Yuling
;
Wu, Meng
;
McManus, Owen B.
;
Li, Min
;
Wu, Jilin
;
Luo, Huai-Rong
;
Cao, Zhengyu
;
Shen, Bing
;
Wang, Hongbo
;
Zhu, Michael X.
;
Hong, Xuechuan
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Adobe PDF(1969Kb)
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View/Download:249/84
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Submit date:2017/08/29
Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way
期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2017, 卷号: 426, 期号: 1-2, 页码: 101-109
Authors:
Ding, Ai-Jun
;
Wu, Gui-Sheng
;
Tang, Bin
;
Hong, Xuechuan
;
Zhu, Michael X.
;
Luo, Huai-Rong
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  |  
Adobe PDF(557Kb)
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View/Download:333/101
  |  
Submit date:2017/05/19
Aging
Benzimidazole Derivative M084
Caenorhabditis Elegans
Lifespan
Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice
期刊论文
PLOS ONE, 2015, 卷号: 10, 期号: 8
Authors:
Yang, Li-Ping
;
Jiang, Fang-Jie
;
Wu, Gui-Sheng
;
Deng, Ke
;
Wen, Meng
;
Zhou, Xiaoju
;
Hong, Xuechuan
;
Zhu, Michael X.
;
Luo, Huai-Rong
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Submit date:2016/01/19
Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels
期刊论文
BRITISH JOURNAL OF PHARMACOLOGY, 2015, 卷号: 172, 期号: 14, 页码: 3495-3509
Authors:
Zhu, Yingmin
;
Lu, Yungang
;
Qu, Chunrong
;
Miller, Melissa
;
Tian, Jinbin
;
Thakur, Dhananjay P.
;
Zhu, Jinmei
;
Deng, Zixin
;
Hu, Xianming
;
Wu, Meng
;
McManus, Owen B.
;
Li, Min
;
Hong, Xuechuan
;
Zhu, Michael X.
;
Luo, Huai-Rong
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Adobe PDF(2298Kb)
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View/Download:265/57
  |  
Submit date:2015/12/15
吡唑并嘧啶类化合物及其药物组合物和其在制药中的应用
专利
专利类型: 发明, 专利号: CN201310666552.1, 申请日期: 2013-12-10, 公开日期: 2014-04-02
Inventors:
罗怀容
;
洪学传
;
朱曦
;
朱进妹
;
吴桂生
;
邓子新
;
朱颖旻
;
陆云刚
;
邓科
;
瞿春容
Adobe PDF(1569Kb)
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View/Download:495/6
  |  
Submit date:2016/12/19
Synthesis and neurotrophic activity evaluation of amaryllidaceae alkaloids
期刊论文
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 卷号: 246
Authors:
Luo, Huairong
;
He, Maomao
;
Zhu, Jinmei
;
Wu, Chunfeng
;
Deng, Zixin
;
Hong, Xuechuan
Favorite
  |  
View/Download:280/0
  |  
Submit date:2015/05/14
Synthesis, biological evaluation and molecular modeling of substituted 2-aminobenzimidazoles as novel inhibitors of acetylcholinesterase and butyrylcholinesterase
期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2013, 卷号: 21, 期号: 14, 页码: 4218-4224
Authors:
Zhu, Jinmei
;
Wu, Chun-Feng
;
Li, Xiaobing
;
Wu, Gui-Sheng
;
Xie, Shan
;
Hu, Qian-Nan
;
Deng, Zixin
;
Zhu, Michael X.
;
Luo, Huai-Rong
;
Hong, Xuechuan
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Adobe PDF(1174Kb)
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Submit date:2013/10/16
Alzheimer's Disease
Acetylcholinesterase
Butyrylcholinesterase
Molecular Modeling
2-aminobenzimidazole
苯并咪唑及其衍生物,其药物组合物及其应用
专利
专利类型: 发明, 专利号: CN201210512291.3, 申请日期: 2012-12-04, 公开日期: 2013-05-29
Inventors:
罗怀容
;
洪学传
;
邓子新
;
吴桂生
;
丁爱军
;
朱进妹
;
邹系胜
Adobe PDF(1090Kb)
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View/Download:176/6
  |  
Submit date:2016/12/19
苯并咪唑及其衍生物,其药物组合物及其在制备抗抑郁药物中的应用
专利
专利类型: 发明, 专利号: CN201210512505.7, 申请日期: 2012-12-04, 公开日期: 2013-05-29
Inventors:
罗怀容
;
洪学传
;
邓子新
;
吴桂生
;
杨丽萍
;
朱进妹
;
刘磊
Adobe PDF(938Kb)
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View/Download:180/5
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Submit date:2016/12/19
Metal-free direct amidation of peptidyl thiol esters with alpha-amino acid esters
期刊论文
GREEN CHEMISTRY, 2011, 卷号: 13, 期号: 10, 页码: 2723-2726
Authors:
Chen, Hao
;
He, Maomao
;
Wang, Yaya
;
Zhai, Linhui
;
Cui, Yongbo
;
Li, Yangyan
;
Li, Yan
;
Zhou, Haibing
;
Hong, Xuechuan
;
Deng, Zixin
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View/Download:404/121
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Submit date:2012/07/25
Native Chemical Ligation
Catalyzed Double Carbohydroamination
Amide Synthesis
Mild Amidation
One-pot
Oxidative Amidation
General-solution
Aldehydes
Alcohols
Efficient