| Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels | |
Zhu, Yingmin1; Lu, Yungang1,2; Qu, Chunrong3; Miller, Melissa4,5; Tian, Jinbin1; Thakur, Dhananjay P.1; Zhu, Jinmei3; Deng, Zixin3; Hu, Xianming2; Wu, Meng4,5; McManus, Owen B.4,5; Li, Min4,5; Hong, Xuechuan3; Zhu, Michael X.1; Luo, Huai-Rong6
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| 2015-07-01 | |
| 发表期刊 | BRITISH JOURNAL OF PHARMACOLOGY
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| 卷号 | 172期号:14页码:3495-3509 |
| 摘要 | Background and PurposeTransient receptor potential canonical (TRPC) channels play important roles in a broad array of physiological functions and are involved in various diseases. However, due to a lack of potent subtype-specific inhibitors the exact roles of TRPC channels in physiological and pathophysiological conditions have not been elucidated. |
| DOI | 10.1111/bph.13140 |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000356976300004 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/24937 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Univ Texas Hlth Sci Ctr Houston, Dept Integrat Biol & Pharmacol, Houston, TX 77030 USA 2.Guangzhou Med Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China 3.Wuhan Univ, State Key Lab Virol, Key Lab Combinatorial Biosynth & Drug Discovery, Minist Educ,Sch Pharmaceut Sci, Wuhan 430072, Hubei, Peoples R China 4.Johns Hopkins Univ, Sch Med, Dept Neurosci, High Throughput Biol Ctr, Baltimore, MD 21205 USA 5.Johns Hopkins Univ, Johns Hopkins Ion Channel Ctr, Baltimore, MD USA 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Yingmin,Lu, Yungang,Qu, Chunrong,et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels[J]. BRITISH JOURNAL OF PHARMACOLOGY,2015,172(14):3495-3509. |
| APA | Zhu, Yingmin.,Lu, Yungang.,Qu, Chunrong.,Miller, Melissa.,Tian, Jinbin.,...&Luo, Huai-Rong.(2015).Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.BRITISH JOURNAL OF PHARMACOLOGY,172(14),3495-3509. |
| MLA | Zhu, Yingmin,et al."Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels".BRITISH JOURNAL OF PHARMACOLOGY 172.14(2015):3495-3509. |
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| zhu2015.pdf（2298KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | 浏览 下载 | |
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