| Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels | |
Zhu, Yingmin1; Lu, Yungang1,2; Qu, Chunrong3; Miller, Melissa4,5; Tian, Jinbin1; Thakur, Dhananjay P.1; Zhu, Jinmei3; Deng, Zixin3; Hu, Xianming2; Wu, Meng4,5; McManus, Owen B.4,5; Li, Min4,5; Hong, Xuechuan3; Zhu, Michael X.1; Luo, Huai-Rong6
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| 2015-07-01 | |
| Source Publication | BRITISH JOURNAL OF PHARMACOLOGY
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| Volume | 172Issue:14Pages:3495-3509 |
| Abstract | Background and PurposeTransient receptor potential canonical (TRPC) channels play important roles in a broad array of physiological functions and are involved in various diseases. However, due to a lack of potent subtype-specific inhibitors the exact roles of TRPC channels in physiological and pathophysiological conditions have not been elucidated. |
| DOI | 10.1111/bph.13140 |
| Indexed By | SCI |
| Language | 英语 |
| WOS Research Area | Pharmacology & Pharmacy |
| WOS Subject | Pharmacology & Pharmacy |
| WOS ID | WOS:000356976300004 |
| Citation statistics | |
| Document Type | 期刊论文 |
| Identifier | http://ir.kib.ac.cn/handle/151853/24937 |
| Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
| Affiliation | 1.Univ Texas Hlth Sci Ctr Houston, Dept Integrat Biol & Pharmacol, Houston, TX 77030 USA 2.Guangzhou Med Univ, Affiliated Hosp 3, Guangzhou, Guangdong, Peoples R China 3.Wuhan Univ, State Key Lab Virol, Key Lab Combinatorial Biosynth & Drug Discovery, Minist Educ,Sch Pharmaceut Sci, Wuhan 430072, Hubei, Peoples R China 4.Johns Hopkins Univ, Sch Med, Dept Neurosci, High Throughput Biol Ctr, Baltimore, MD 21205 USA 5.Johns Hopkins Univ, Johns Hopkins Ion Channel Ctr, Baltimore, MD USA 6.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming, Yunnan, Peoples R China |
| Recommended Citation GB/T 7714 | Zhu, Yingmin,Lu, Yungang,Qu, Chunrong,et al. Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels[J]. BRITISH JOURNAL OF PHARMACOLOGY,2015,172(14):3495-3509. |
| APA | Zhu, Yingmin.,Lu, Yungang.,Qu, Chunrong.,Miller, Melissa.,Tian, Jinbin.,...&Luo, Huai-Rong.(2015).Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels.BRITISH JOURNAL OF PHARMACOLOGY,172(14),3495-3509. |
| MLA | Zhu, Yingmin,et al."Identification and optimization of 2-aminobenzimidazole derivatives as novel inhibitors of TRPC4 and TRPC5 channels".BRITISH JOURNAL OF PHARMACOLOGY 172.14(2015):3495-3509. |
| Files in This Item: | ||||||
| File Name/Size | DocType | Version | Access | License | ||
| zhu2015.pdf（2298KB） | 期刊论文 | 作者接受稿 | 开放获取 | CC BY-NC-SA | View Download | |
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