| Unusual Spirodecane Sesquiterpenes and a Fumagillol Analogue from Cordyceps ophioglossoides | |
| Sun, Yisheng1; Zhao, Zhao1; Feng, Qiangsheng1; Xu, Qinqin1; Lu, Longxian1; Liu, Ji-Kai3; Zhang, Ling3; Wu, Bin2; Li, Yong-Quan1 | |
| 通讯作者 | Wu, B (reprint author), Zhejiang Univ, Dept Ocean Sci & Engn, Hangzhou 310058, Zhejiang, Peoples R China.，wubin@zju.edu.cn ; lyq@zju.edu.cn |
| 2013 | |
| 发表期刊 | HELVETICA CHIMICA ACTA
 |
| ISSN | 0018-019X |
| 卷号 | 96期号:1页码:76-84 |
| 摘要 | Investigation of the cultured mycelia of Cordyceps ophioglossoides resulted in the isolation and characterization of three new unusual spiro[4.5]decane sesquiterpenes, cordycepol A (1), cordycepol B (2), and cordycepol C (3), and a new fumagillol analogue, cordycol (4). Their structures were established by spectroscopic means. The cytotoxic activities were also evaluated, compounds 3 and 4 showing their IC50 values in the range of 1233 mu g/ml against HeLa and HepG2 (Table 3). In addition, 3 and 4 were not obviously harmful towards normal liver cell lines LO2, showing IC50 values above 80 mu g/ml. |
| 关键词 | Cordyceps Ophioglossoides CordyA?-?cepols a?-?A?-?c Cordycol Cytotoxic Activity Fungi |
| 学科领域 | Chemistry |
| 收录类别 | SCI ; IC |
| 语种 | 英语 |
| WOS记录号 | WOS:000313902600007 |
| 引用统计 | |
| 文献类型 | 期刊论文 |
| 条目标识符 | http://ir.kib.ac.cn/handle/151853/16208 |
| 专题 | 植物化学与西部植物资源持续利用国家重点实验室 |
| 作者单位 | 1.Zhejiang Univ, Coll Life Sci, Hangzhou 310058, Zhejiang, Peoples R China 2.Zhejiang Univ, Dept Ocean Sci & Engn, Hangzhou 310058, Zhejiang, Peoples R China 3.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources W China, Kunming 650204, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Yisheng,Zhao, Zhao,Feng, Qiangsheng,et al. Unusual Spirodecane Sesquiterpenes and a Fumagillol Analogue from Cordyceps ophioglossoides[J]. HELVETICA CHIMICA ACTA,2013,96(1):76-84. |
| APA | Sun, Yisheng.,Zhao, Zhao.,Feng, Qiangsheng.,Xu, Qinqin.,Lu, Longxian.,...&Li, Yong-Quan.(2013).Unusual Spirodecane Sesquiterpenes and a Fumagillol Analogue from Cordyceps ophioglossoides.HELVETICA CHIMICA ACTA,96(1),76-84. |
| MLA | Sun, Yisheng,et al."Unusual Spirodecane Sesquiterpenes and a Fumagillol Analogue from Cordyceps ophioglossoides".HELVETICA CHIMICA ACTA 96.1(2013):76-84. |
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