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Acetyl-macrocalin B suppresses tumor growth in esophageal squamous cell carcinoma and exhibits synergistic anti-cancer effects with the Chk1/2 inhibitor AZD7762 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2019, 卷号: 365, 页码: 71-83
作者:  Wang, Jing-Nan;  Che, Yun;  Yuan, Zu-Yang;  Lu, Zhi-Liang;  Li, Yuan;  Zhang, Zhi-Rong;  Li, Ning;  Li, Ren-Da;  Wan, Jun;  Sun, Han-Dong;  Sun, Nan;  Puno, Pema-Tenzin;  He, Jie
浏览  |  Adobe PDF(3457Kb)  |  收藏  |  浏览/下载：302/67  |  提交时间：2019/03/18
Acetyl-macrocalin B  Reactive oxygen species  p38 MAPK  Chk1/Chk2  Esophageal squamous cell carcinoma  
Maoeriocalysins A-D, four novel ent-kaurane diterpenoids from Isodon eriocalyx and their structure determination utilizing quantum chemical calculation in conjunction with quantitative interproton distance analysis 期刊论文
ORGANIC CHEMISTRY FRONTIERS, 2019, 卷号: 6, 期号: 1, 页码: 45-53
作者:  Yang, Qian;  Hu, Kun;  Yan, Bing-Chao;  Liu, Miao;  Li, Xiao-Nian;  Sun, Han-Dong;  Puno, Pema-Tenzin
浏览  |  Adobe PDF(1823Kb)  |  收藏  |  浏览/下载：234/33  |  提交时间：2019/03/18
Adenanthin, a Natural ent-Kaurane Diterpenoid Isolated from the Herb Isodon adenantha Inhibits Adipogenesis and the Development of Obesity by Regulation of ROS 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 1, 页码: 16
作者:  Hu, Jing;  Li, Xingren;  Tian, Weifeng;  Lu, Yanting;  Xu, Yuhui;  Wang, Fang;  Qin, Wanying;  Ma, Xiuli;  Puno, Pema-Tenzin;  Xiong, Wenyong
浏览  |  Adobe PDF(3093Kb)  |  收藏  |  浏览/下载：322/22  |  提交时间：2019/03/18
adenanthin  adipogenesis  reactive oxygen species  obesity  3T3-L1  
Functional roles of eriocalyxin B in zebrafish revealed by transcriptome analysis 期刊论文
MOLECULAR OMICS, 2018, 卷号: 14, 期号: 3, 页码: 156-169
作者:  Zhou, Xunian;  Cao, Cyanne Ye;  Wan, Angel Tsz-Yau;  Yue, Grace Gar-Lee;  Kwok, Frankie Hin-Fai;  Fung, Kwok-Pui;  Sun, Handong;  Lau, Clara Bik-San;  Puno, Pema-Tenzin;  Tsui, Stephen Kwok-Wing
收藏  |  浏览/下载：328/0  |  提交时间：2018/07/16
Diterpenoids from Isodon species: an update 期刊论文
NATURAL PRODUCT REPORTS, 2017, 卷号: 34, 期号: 9, 页码: 1090-1140
作者:  Liu, Miao;  Wang, Wei-Guang;  Sun, Han-Dong;  Pu, Jian-Xin
浏览  |  Adobe PDF(10292Kb)  |  收藏  |  浏览/下载：263/30  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Japonica Var. Glaucocalyx  Nf-kappa-b  Hepatocellular-carcinoma Cells  C-h Functionalization  Dna-binding Activity  Serra Maxim. Hara  Maoecrystal-v  Abietane Diterpenoids  Chemical-constituents  
Dibenzocyclooctadiene lignans from Kadsura heteroclita 期刊论文
FITOTERAPIA, 2017, 卷号: 119, 页码: 150-157
作者:  Luo, Yuan-Qing;  Liu, Miao;  Wen, Jin;  Wang, Wei-Guang;  Hu, Kun;  Li, Xiao-Nian;  Du, Xue;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(684Kb)  |  收藏  |  浏览/下载：277/112  |  提交时间：2017/07/31
Kadsura Heteroclita  Dibenzocyclooctadiene Lignans  Cytotoxicity  
The Natural Diterpenoid Isoforretin A Inhibits Thioredoxin-1 and Triggers Potent ROS-Mediated Antitumor Effects 期刊论文
CANCER RESEARCH, 2017, 卷号: 77, 期号: 4, 页码: 926-936
作者:  Sun, Xiaoyan;  Wang, Weiguang;  Chen, Jiao;  Cai, Xueting;  Yang, Jie;  Yang, Yang;  Yan, Huaijiang;  Cheng, Xiaolan;  Ye, Juan;  Lu, Wuguang;  Hu, Chunping;  Sun, Handong;  Pu, Jianxin;  Cao, Peng
浏览  |  Adobe PDF(1370Kb)  |  收藏  |  浏览/下载：450/205  |  提交时间：2017/02/28
Eriocalyxin B, a Novel Autophagy Inducer, Exerts Anti-tumor Activity Through the Suppression of Akt/mTOR/p70S6K Signaling Pathway In breast Cancer 期刊论文
Biochemical Pharmacology, 2017, 卷号: 142, 页码: 58–70
作者:  Xunian Zhou;  Grace Gar-Lee Yue;  Andrew Man-Lok Chan;   Stephen Kwok-Wing Tsui;  Kwok-Pui Fung;   Handong Sun;  Jianxin Pu;  Clara Bik-San Lau
浏览  |  Adobe PDF(5871Kb)  |  收藏  |  浏览/下载：209/55  |  提交时间：2017/11/20
Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys 期刊论文
SCIENCE CHINA-CHEMISTRY, 2016, 卷号: 59, 期号: 9, 页码: 1211-1215
作者:  Yang, Jin;  An, Yaqi;  Wu, Haiyan;  Liu, Miao;  Wang, Weiguang;  Du, Xue;  Li, Yan;  Pu, Jianxin;  Sun, Handong
Adobe PDF(566Kb)  |  收藏  |  浏览/下载：490/47  |  提交时间：2016/11/04
Isodon Phyllostachys  Diterpenoid  Ent-kaurane  Ent-abietane  
Structural Characterization of Kadcoccinin A: A Sesquiterpenoid with a Tricyclo[4.4.0.0(3,10)]decane Scaffold from Kadsura coccinea 期刊论文
ORGANIC LETTERS, 2016, 卷号: 18, 期号: 9, 页码: 2284-2287
作者:  Hu, Zheng-Xi;  Shi, Yi-Ming;  Wang, Wei-Guang;  Tang, Jian-Wei;  Zhou, Min;  Du, Xue;  Zhang, Yong-Hui;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(986Kb)  |  收藏  |  浏览/下载：376/57  |  提交时间：2016/08/22