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题名: Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys
作者: Yang, Jin; An, Yaqi; Wu, Haiyan; Liu, Miao; Wang, Weiguang; Du, Xue; null(李艳); Pu, Jianxin; null(孙汉董)
刊名: SCIENCE CHINA-CHEMISTRY
关键词: Isodon phyllostachys ; diterpenoid ; ent-kaurane ; ent-abietane
英文摘要: Four new diterpenoids, phyllostachysins I-L (1-4), along with a known one, hebeiabinin B (5), were isolated from the aerial parts of Isodon phyllostachys (I. phyllostachys). Compounds 1 and 2 feature an ent-kaurane backbone, and 3, 4 and 5 bear an ent-abietane skeleton. Their structures were elucidated by means of spectroscopic analysis. Compounds 3 and 4 exhibited significant cytotoxic activity against human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and strongly inhibited NO production in LPS-stimulated RAW264.7 cells.
出版日期: 2016-09-01
卷号: 59, 期号:9, 页码:1211-1215
DOI标识: 10.1007/s11426-016-0049-4
语种: 英语
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内容类型: 期刊论文
URI标识: http://ir.kib.ac.cn/handle/151853/28629
Appears in Collections:植物化学与西部植物资源持续利用国家重点实验室_期刊论文

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