Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys | |
Yang, Jin; An, Yaqi; Wu, Haiyan; Liu, Miao; Wang, Weiguang; Du, Xue; Li, Yan![]() ![]() ![]() | |
2016-09-01 | |
Source Publication | SCIENCE CHINA-CHEMISTRY
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Volume | 59Issue:9Pages:1211-1215 |
Abstract | Four new diterpenoids, phyllostachysins I-L (1-4), along with a known one, hebeiabinin B (5), were isolated from the aerial parts of Isodon phyllostachys (I. phyllostachys). Compounds 1 and 2 feature an ent-kaurane backbone, and 3, 4 and 5 bear an ent-abietane skeleton. Their structures were elucidated by means of spectroscopic analysis. Compounds 3 and 4 exhibited significant cytotoxic activity against human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and strongly inhibited NO production in LPS-stimulated RAW264.7 cells. |
Keyword | Isodon Phyllostachys Diterpenoid Ent-kaurane Ent-abietane |
DOI | 10.1007/s11426-016-0049-4 |
Indexed By | SCI |
Language | 英语 |
WOS ID | WOS:000382943500014 |
Citation statistics | |
Document Type | 期刊论文 |
Identifier | http://ir.kib.ac.cn/handle/151853/28629 |
Collection | 植物化学与西部植物资源持续利用国家重点实验室 |
Recommended Citation GB/T 7714 | Yang, Jin,An, Yaqi,Wu, Haiyan,et al. Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys[J]. SCIENCE CHINA-CHEMISTRY,2016,59(9):1211-1215. |
APA | Yang, Jin.,An, Yaqi.,Wu, Haiyan.,Liu, Miao.,Wang, Weiguang.,...&Sun, Handong.(2016).Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys.SCIENCE CHINA-CHEMISTRY,59(9),1211-1215. |
MLA | Yang, Jin,et al."Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys".SCIENCE CHINA-CHEMISTRY 59.9(2016):1211-1215. |
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