Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys
Yang, Jin; An, Yaqi; Wu, Haiyan; Liu, Miao; Wang, Weiguang; Du, Xue; Li, Yan; Pu, Jianxin; Sun, Handong
2016-09-01
Source PublicationSCIENCE CHINA-CHEMISTRY
Volume59Issue:9Pages:1211-1215
AbstractFour new diterpenoids, phyllostachysins I-L (1-4), along with a known one, hebeiabinin B (5), were isolated from the aerial parts of Isodon phyllostachys (I. phyllostachys). Compounds 1 and 2 feature an ent-kaurane backbone, and 3, 4 and 5 bear an ent-abietane skeleton. Their structures were elucidated by means of spectroscopic analysis. Compounds 3 and 4 exhibited significant cytotoxic activity against human tumor cell lines (HL-60, SMMC-7721, A-549, MCF-7 and SW-480), and strongly inhibited NO production in LPS-stimulated RAW264.7 cells.
KeywordIsodon Phyllostachys Diterpenoid Ent-kaurane Ent-abietane
DOI10.1007/s11426-016-0049-4
Indexed BySCI
Language英语
WOS Research AreaChemistry
WOS SubjectChemistry, Multidisciplinary
WOS IDWOS:000382943500014
Citation statistics
Cited Times:1[WOS]   [WOS Record]     [Related Records in WOS]
Document Type期刊论文
Identifierhttp://ir.kib.ac.cn/handle/151853/28629
Collection植物化学与西部植物资源持续利用国家重点实验室
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GB/T 7714
Yang, Jin,An, Yaqi,Wu, Haiyan,et al. Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys[J]. SCIENCE CHINA-CHEMISTRY,2016,59(9):1211-1215.
APA Yang, Jin.,An, Yaqi.,Wu, Haiyan.,Liu, Miao.,Wang, Weiguang.,...&Sun, Handong.(2016).Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys.SCIENCE CHINA-CHEMISTRY,59(9),1211-1215.
MLA Yang, Jin,et al."Ent-kaurane and ent-abietane diterpenoids from Isodon phyllostachys".SCIENCE CHINA-CHEMISTRY 59.9(2016):1211-1215.
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