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Physalis peruviana-Derived 4 beta-Hydroxywithanolide E, a Novel Antagonist of Wnt Signaling, Inhibits Colorectal Cancer In Vitro and In Vivo 期刊论文
MOLECULES, 2019, 卷号: 24, 期号: 6, 页码: 13
作者:  Ye, Zhen-Nan;  Yuan, Feng;  Liu, Jie-Qing;  Peng, Xing-Rong;  An, Tao;  Li, Xue;  Kong, Ling-Mei;  Qiu, Ming-Hua;  Li, Yan
浏览  |  Adobe PDF(3189Kb)  |  收藏  |  浏览/下载：212/40  |  提交时间：2019/07/29
4 beta HWE  Wnt signaling pathway  beta-catenin  colorectal cancer  
Ganolearic Acid A, a Hexanorlanostane Triterpenoid with a 3/5/6/5-Fused Tetracyclic Skeleton from Ganoderma cochlear 期刊论文
JOURNAL OF ORGANIC CHEMISTRY, 2018, 卷号: 83, 期号: 21, 页码: 13178-13183
作者:  Peng, Xing-Rong;  Huang, Yan-Jie;  Lu, Shuang-Yang;  Yang, Jing;  Qiu, Ming-Hua
浏览  |  Adobe PDF(319Kb)  |  收藏  |  浏览/下载：567/167  |  提交时间：2018/12/18
A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells 期刊论文
ONCOLOGY REPORTS, 2017, 卷号: 37, 期号: 4, 页码: 2079-2086
作者:  Dai, Xiaoli;  Liu, Jing;  Nian, Yin;  Qiu, Ming-Hua;  Luo, Ying;  Zhang, Jihong
Adobe PDF(1057Kb)  |  收藏  |  浏览/下载：261/64  |  提交时间：2017/06/01
Cimicifuga  Apoptosis  Autophagy  Colon Cancer Cells  
New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment 期刊论文
SCIENTIFIC REPORTS, 2016, 卷号: 6, 期号: 1, 页码: 1
作者:  Yue, Grace Gar-Lee;  Xie, Sida;  Lee, Julia Kin-Ming;  Kwok, Hin-Fai;  Gao, Si;  Nian, Yin;  Wu, Xiao-Xiao;  Wong, Chun-Kwok;  Qiu, Ming-Hua;  Lau, Clara Bik-San
Adobe PDF(2501Kb)  |  收藏  |  浏览/下载：297/60  |  提交时间：2016/12/21
The in Vitro and in Vivo Antitumor Activities of Tetracyclic Triterpenoids Compounds Actein and 26-Deoxyactein Isolated from Rhizome of Cimicifuga foetida L. 期刊论文
MOLECULES, 2016, 卷号: 21, 期号: 8, 页码: 1001
作者:  Wu, Desong;  Yao, Qi;  Chen, Yajuan;  Hu, Xiaodong;  Qing, Chen;  Qiu, Minghua
浏览  |  Adobe PDF(2842Kb)  |  收藏  |  浏览/下载：228/40  |  提交时间：2017/01/05
Actein  26-deoxyactein  Antitumor Activity  Ic50  Cell Cycle  
KHF16 is a Leading Structure from Cimicifuga foetida that Suppresses Breast Cancer Partially by Inhibiting the NF-kappa B Signaling Pathway 期刊论文
THERANOSTICS, 2016, 卷号: 6, 期号: 6, 页码: 875-886
作者:  Kong, Yanjie;  Li, Fubin;  Nian, Yin;  Zhou, Zhongmei;  Yang, Runxiang;  Qiu, Ming-Hua;  Chen, Ceshi
浏览  |  Adobe PDF(2520Kb)  |  收藏  |  浏览/下载：204/67  |  提交时间：2016/08/22
Khf16  Cycloartane Triterpenoid  Triple Negative Breast Cancer  Cell Cycle  Apoptosis  Nf-kappa b  
Cucurbitacin E Induces Cell Cycle G2/M Phase Arrest and Apoptosis in Triple Negative Breast Cancer 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 7, 页码: e103760
作者:  Kong, Yanjie;  Chen, Jianchao;  Zhou, Zhongmei;  Xia, Houjun;  Qiu, Ming-Hua;  Chen, Ceshi;  Qiu,MH (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming,Yunnan,Peoples R China.;  qiuminghua@mail.kib.ac.cn;  chenc@mail.kiz.ac.cn
浏览  |  Adobe PDF(3184Kb)  |  收藏  |  浏览/下载：230/45  |  提交时间：2014/11/25
Inhibitory-activity  Signaling Pathway  Carcinoma  Growth  Activation  
3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 5, 页码: 925-938
作者:  Yi, Ping;  Fang, Xin;  Qiu, Minghua
Adobe PDF(2704Kb)  |  收藏  |  浏览/下载：343/99  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  Comsia  Checkpoint Kinase Weel  
3D-QSAR and docking studies of aminopyridine carboxamide inhibitors of c-Jun N-terminal kinase-1 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2008, 卷号: 43, 期号: 3, 页码: 604-613
作者:  Yi, Ping;  Qiu, Minghua
Adobe PDF(2801Kb)  |  收藏  |  浏览/下载：322/165  |  提交时间：2011/11/24
3d-qsar  Gold  Comfa  C-jun N-terminal Kinase-1