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Steroidal saponins with cytotoxic effects from the rhizomes of Asparagus cochinchinensis 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 115, 页码: 105237
作者:  Liu,Bo;  Li,Bingxin;  Zhou,Di;  Wen,Xiaoyan;  Wang,Yajun;  Chen,Gang;  Li,Ning
收藏  |  浏览/下载:55/0  |  提交时间:2022/04/02
Asparagus cochinchinensis  Steroidal  NCI-H460 cell line  Cytotoxic  Apoptosis  GLYCOSIDES  CELL  CANCER  
Artematrovirenins A-P, guaiane-type sesquiterpenoids with cytotoxicities against two hepatoma cell lines from Artemisia atrovirens 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 114, 页码: 105072
作者:  Su,Li-Hua;  Ma,Yun-Bao;  Geng,Chang-An;  Li,Tian-Ze;  Huang,Xiao-Yan;  Hu,Jing;  Zhang,Xin;  Tang,Shuang;  Shen,Cheng;  Gao,Zhen;  Zhang,Xue-Mei;  Chen,Ji-Jun
浏览  |  Adobe PDF(2611Kb)  |  收藏  |  浏览/下载:139/72  |  提交时间:2022/04/02
Artemisia atrovirens  guaiane-type sesquiterpenoids  artematrovirenins A-P  HepG2 and Huh7 cell lines  antihepatic cytotoxicity  LACTONES  CONSTITUENTS  GUAIANOLIDES  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载:111/31  |  提交时间:2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
An efficient and concise synthesis of a selective small molecule non-peptide inhibitor of cathepsin L: KGP94 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 116, 页码: 105317
作者:  Munikishore,Rachakunta;  Wang,Liang-Liang;  Zhang,Shuqun;  Zhao,Qin-Shi;  Zuo,Zhili
浏览  |  Adobe PDF(523Kb)  |  收藏  |  浏览/下载:73/19  |  提交时间:2022/04/02
Cathepsin L  small-molecule inhibitor  gram-scale synthesis  KGP94  cancer  FUNCTIONALIZED BENZOPHENONE  BIOLOGICAL EVALUATION  TUMOR PROGRESSION  CELL INVASION  EXPRESSION  ANALOGS  SUPPRESSION  DERIVATIVES  ACID  
Polymethylated acylphloroglucinols from Rhodomyrtus tomentosa exert acetylcholinesterase inhibitory effects 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 107, 页码: 104519
作者:  Qin,Xu-Jie;  Liu,Hui;  Li,Pan-Pan;  Ni,Wei;  He,Li;  Khan,Afsar;  Hao,Xiao-Jiang;  Liu,Hai-Yang
Adobe PDF(2105Kb)  |  收藏  |  浏览/下载:100/44  |  提交时间:2022/04/02
Rhodomyrtus tomentosa  Polymethylated acyphloroglucinols  AChE inhibitory effect  Molecular docking  PHLOROGLUCINOL MEROTERPENOIDS  LEAVES  DERIVATIVES  TWIGS  BETA  
Discovery of pseudolaric acid A as a new Hsp90 inhibitor uncovers its potential anticancer mechanism 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 112, 页码: 104963
作者:  Liu,Jiangxin;  Wu,Xing-De;  Li,Wenyan;  Yuan,Zaifeng;  Yang,Kun;  Zhao,Qin-Shi
Adobe PDF(3665Kb)  |  收藏  |  浏览/下载:68/9  |  提交时间:2022/04/02
Pseudolaric acid A  Hsp90 inhibitor  Apoptosis  NMR  Structure-activity relationship  Photoaffinity-based probe  Protein-ligand interaction  MOLECULAR CHAPERONE  PROTEIN  TARGET  CANCER  KINASE  NMR  IDENTIFICATION  SELECTIVITY  BINDING  DESIGN  
Neuroprotective schinortriterpenoids from Schisandra neglecta collected in Medog County, Tibet, China 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 110, 页码: 104785
作者:  Wang,Bin;  Hu,Kun;  Li,Xiao-Nian;  Sun,Han-Dong;  Qin,Hong-Bo;  Puno,Pema-Tenzin
Adobe PDF(2463Kb)  |  收藏  |  浏览/下载:80/16  |  提交时间:2022/04/02
Schisandra neglecta  16  17-secopreschisanartane-type  schinortriterpenoids  Schisdilactones K?U  Quantum chemical calculation  Neuroprotective activity  DIBENZOCYCLOOCTADIENE LIGNANS  NORTRITERPENOIDS  CHINENSIS  STEMS  7,8-SECOLIGNANS  TRITERPENOIDS  
Microbial transformation of diosgenin to diosgenone by Wickerhamomyces anomalus JQ-1 obtained from Naxi traditional Jiu Qu 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Li, Liangqun;  Zhao, Yanqiang;  Lang, Bayi;  Xie, Yuying;  Meng, Manfred Shaowu;  He, Yun;  Yang, Lixin;  Liu, Aizhong
Adobe PDF(2142Kb)  |  收藏  |  浏览/下载:210/85  |  提交时间:2021/01/05
Cytotoxic sesquiterpenoids against hepatic stellate cell line LX2 from Artemisia lavandulaefolia 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Shen, Cheng;  Huang, Xiao-Yan;  Geng, Chang-An;  Li, Tian-Ze;  Wang, Jin-Ping;  Tang, Shuang;  Su, Li-Hua;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
Adobe PDF(2199Kb)  |  收藏  |  浏览/下载:152/34  |  提交时间:2021/01/05
Ten new glycosides, carissaedulosides A-J from the root barks of Carissa edulis and their cytotoxicities 期刊论文
BIOORGANIC CHEMISTRY, 2020
作者:  Kaunda, Joseph Sakah;  Qin, Xu-Jie;  Yang, Xing-Zhi;  Mwitari, Peter Githaiga;  Zhu, Hong-Tao;  Wang, Dong;  Zhang, Ying-Jun
Adobe PDF(3588Kb)  |  收藏  |  浏览/下载:135/61  |  提交时间:2021/01/05