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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载：111/18  |  提交时间：2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
Melanin precursors mediated adaption to temperature changes in fungus and animal via inhibition of lipid-mediated ferroptosis 期刊论文
SCIENCE CHINA-LIFE SCIENCES, 2023
作者:  Yang,Xiaoyu;  Chen,Yonghong;  Zhang,Longlong;  He,Jiangbo;  Wu,Qunfu;  Li,Shuhong;  Wang,Donglou;  Gou,Jianghui;  Wu,Zhuang;  Zhang,Keqin;  Li,Shenghong;  Niu,Xuemei
浏览  |  Adobe PDF(3409Kb)  |  收藏  |  浏览/下载：72/13  |  提交时间：2024/05/09
melanin  precursor  lipid  ferroptosis  temperature change  anti-cold  COLD STRESS  PIGMENTATION  PEROXIDATION  MOUSE  
A Cryptic Plant Terpene Cyclase Producing Unconventional 18-and 14-Membered Macrocyclic C-25 and C-20 Terpenoids with Immunosuppressive Activity 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 卷号: 60, 期号: 48, 页码: 25468-25476
作者:  Chen,Yue-Gui;  Li,De-Sen;  Ling,Yi;  Liu,Yan-Chun;  Zuo,Zhi-Li;  Gan,Li-She;  Luo,Shi-Hong;  Hua,Juan;  Chen,Ding-Yuan;  Xu,Fan;  Li,Man;  Guo,Kai;  Liu,Yan;  Gershenzon,Jonathan;  Li,Sheng-Hong
浏览  |  Adobe PDF(2177Kb)  |  收藏  |  浏览/下载：177/69  |  提交时间：2022/04/02
enzyme engineering  immunosuppressive activity  Leucosceptrum canum  macrocyclic terpenoids  sesterterpene synthase  GERANYLFARNESYL DIPHOSPHATE SYNTHASE  GLANDULAR TRICHOMES  LEUCOSCEPTRUM-CANUM  SCALE INSECT  SESTERTERPENOIDS  CONVERSION  EVOLUTION  PRECURSOR  HARBOR  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载：102/0  |  提交时间：2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
Para-Aminobenzoic Acid (PABA) Synthase Enhances Thermotolerance of Mushroom Agaricus bisporus 期刊论文
PLOS ONE, 2014, 卷号: 9, 期号: 3, 页码: e91298
作者:  Lu, Zhonglei;  Kong, Xiangxiang;  Lu, Zhaoming;  Xiao, Meixiang;  Chen, Meiyuan;  Zhu, Liang;  Shen, Yuemao;  Hu, Xiangyang;  Song, Siyang
浏览  |  Adobe PDF(4214Kb)  |  收藏  |  浏览/下载：661/70  |  提交时间：2014/05/16
Precursor P-aminobenzoate  Salicylic-acid  Temperature Stress  Oxidative Stress  Gene-expression  Protective Role  Abiotic Stress  Glucose Ester  Abscisic-acid  Salt Stress  
Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice 期刊论文
BIOSCIENCE TRENDS, 2011, 卷号: 5, 期号: 3, 页码: 129-138
作者:  Mishra, Manisha;  Huang, Junjie;  Lee, Yin Yeng;  Chua, Doreen See Kin;  Lin, Xiaoyan;  Hu, Jiang-Miao;  Heese, Klaus
浏览  |  Adobe PDF(389Kb)  |  收藏  |  浏览/下载：205/62  |  提交时间：2015/08/17
Alzheimer's Disease  Beta-amyloid Precursor Protein  Kampo  Neurodegeneration  Traditional Chinese Medicine