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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Ganoapplins A and B with an unprecedented 6/6/6/5/6-fused pentacyclic skeleton from Ganoderma inhibit Tau pathology through activating autophagy
期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 132, 页码: 106375
Authors:
Peng,Xingrong
;
Luo,Rongcan
;
Ran,Xiaoqian
;
Guo,Yarong
;
Yao,Yong-Gang
;
Qiu,Minghua
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Submit date:2024/07/22
Ganoderma
Ganoderma applanatum
Triterpenoid
Autophagy
Tau pathology
Alzheimer?s disease
LANOSTANE-TYPE TRITERPENOIDS
ALZHEIMERS-DISEASE
FRUITING BODIES
NEURODEGENERATION
ACID
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy
期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
Authors:
Yan,Ying
;
Ran,Xiaoqian
;
Wang,Dan
;
Zhang,Xiong
;
Peng,Mingyou
;
Yan,Xiaoyan
;
Tang,Lei
;
Liang,Hong
;
Qin,Xujie
;
Di,Ying-Tong
;
Luo,Rongcan
;
Hao,Xiao-Jiang
;
Yao,Yong-Gang
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Submit date:2024/07/25
UBIQUITIN-PROTEASOME SYSTEM
ALZHEIMERS-DISEASE
CONSTITUENTS
LIMONOIDS
TFEB
NEURODEGENERATION
ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation
期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
Authors:
Zhou,Gui-Feng
;
Tang,Jing
;
Ma,Yuan-Lin
;
Fu,Xian
;
Liu,Jun-Yan
;
Yang,Ren-Zhi
;
Zhang,Hong-Sheng
;
Cai,Xiang-Hai
;
Wang,Jing-Wen
;
Xie,Xiao-Yong
;
Song,Li
;
Luo,Biao
;
Chen,Jian
;
Chen,Long
;
Deng,Xiao-Juan
;
Chen,Guo-Jun
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Submit date:2024/05/09
conophylline
ARL6IP1
5'UTR
FXR1
BACE1 translation
AMYLOID PRECURSOR PROTEIN
A-BETA
TRANSGENIC MICE
MOUSE MODEL
NEURODEGENERATION
EXPRESSION
REDUCTION
MEMBRANE
MEMORY
ER
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway
期刊论文
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
Authors:
Ran,Xiaoqian
;
Lu,Qing-Yun
;
Li,Ying-Yao
;
Pu,Xue-Xue
;
Guo,Yarong
;
Yuan,Ming-Rui
;
Guan,Shi-Peng
;
Sun,Mao
;
Jiao,Lijin
;
Yao,Yong-Gang
;
Di,Ying-Tong
;
Hao,Xiao-Jiang
;
Luo,Rongcan
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Submit date:2024/07/30
Euphorbia peplus L
Euphorbiaceae
Ent-abietane diterpenoid
Euphejolkinolide A
Autophagy-lysosomal pathway
ALZHEIMERS-DISEASE
TAU PATHOLOGY
NEURODEGENERATION
DITERPENOIDS
INHIBITION
MECHANISMS
APOPTOSIS
CELASTROL
PROTEIN
SYSTEM
Recent Studies on Protective Effects of Walnuts against Neuroinflammation
期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 20, 页码: 4360
Authors:
Tan, Bing
;
Wang, Yuxi
;
Zhang, Xudong
;
Sun, Xiangjun
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Submit date:2024/04/30
walnuts
neuroinflammation
neurodegenerative diseases
oxidative stress
antioxidant activity
gut microbes
ALPHA-LINOLENIC ACID
BETA-AMYLOID PROTEIN
NF-KAPPA-B
OXIDATIVE STRESS
COGNITIVE IMPAIRMENT
MEDITERRANEAN DIET
INDUCED ACTIVATION
BV-2 MICROGLIA
ELLAGIC ACID
GALLIC ACID
High-content screening of diterpenoids from Isodon species as autophagy modulators and the functional study of their antiviral activities
期刊论文
CELL BIOLOGY AND TOXICOLOGY, 2021, 卷号: 37, 期号: 5, 页码: 695-713
Authors:
Huang,Lihong
;
Fu,Qiang
;
Dai,Jia-Meng
;
Yan,Bing-Chao
;
Wang,Dawei
;
Puno,Pema-Tenzin
;
Yue,Jianbo
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Submit date:2022/04/02
Diterpenoids
Autophagy
Lysosome
Autophagosome
Enanderinanin J
Dengue virus (DENV)
Zika virus (ZIKV)
Japanese encephalitis virus (JEV)
Enterovirus-A71 (EV-A71)
Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans
期刊论文
CELL CALCIUM, 2021, 卷号: 93, 页码: 102327
Authors:
Yang,Zhong-Lin
;
Chen,Jian-Ning
;
Lu,Yu-Yang
;
Lu,Min
;
Wan,Qin-Li
;
Wu,Gui-Sheng
;
Luo,Huai-Rong
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Submit date:2022/04/02
Inositol polyphosphates
Inositol polyphosphate multikinase
Type I inositol 5-phosphatase
Development
Calcium signaling
Defecation rhythm
C. elegans
C-ELEGANS
PHOSPHOLIPASE-C
CALCIUM
1,4,5-TRISPHOSPHATE
CALCINEURIN
KINASE
IDENTIFICATION
TRISPHOSPHATE
METABOLISM
RECEPTOR
白木香结香树脂部化学成分和内生真菌的分离与鉴定
学位论文
, 2020
Authors:
张璐
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Submit date:2023/11/02
IDO1 及 TDO 抑制剂体外筛选模型的建立及应用
学位论文
, 2020
Authors:
杨坤
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View/Download:55/0
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Submit date:2023/11/02
Isowalsuranolide(HXJ-2351)诱导溶酶体生成及细胞凋亡的分子机制研究
学位论文
, 2020
Authors:
陈远志
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Submit date:2023/11/02