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Hepatic Stellate Celland Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis 期刊论文
ACS NANO, 2023, 卷号: 17, 期号: 23, 页码: 23608-23625
作者:  Niu,Xia;  Meng,Yanan;  Cui,Jinjin;  Li,Rui;  Ding,Xiao;  Niu,Bingyu;  Chang,Ge;  Xu,Ning;  Li,Guiling;  Wang,Yucheng;  Wang,Lulu
浏览  |  Adobe PDF(5563Kb)  |  收藏  |  浏览/下载:155/23  |  提交时间:2024/07/10
liver fibrosis  dihydrotanshinone I  hepaticstellate cells  vitamin A  cyclodextrin  liver microbiome  STRATEGY  THERAPY  TARGET  NANOPARTICLES  PATHWAY  
茵陈蒿和牛尾蒿的抗肝纤维化与抗肝癌活性成分研究 学位论文
: 中国科学院大学, 2022
作者:  高振
Adobe PDF(11670Kb)  |  收藏  |  浏览/下载:140/0  |  提交时间:2024/05/14
茵陈蒿,牛尾蒿,茵陈香豆酸,倍半萜二聚体,倍半萜,抗肝纤维化活性,抗肝癌活性,细胞周期,凋亡  Artemisia capillaris, Artemisia dubia, Coumaric acids, Sesquiterpenoids, Sesquiterpenoid dimers, Antihepatic fibrosis effects, Antihepatoma activity, Cell cycle, Apoptosis  
Lipid Disorders in NAFLD and Chronic Kidney Disease 期刊论文
BIOMEDICINES, 2021, 卷号: 9, 期号: 10, 页码: 1405
作者:  Yang,Meng;  Geng,Chang-An;  Liu,Xinguang;  Guan,Min
收藏  |  浏览/下载:144/0  |  提交时间:2022/04/02
lipid  NAFLD  chronic kidney disease  NONALCOHOLIC FATTY LIVER  ENDOPLASMIC-RETICULUM STRESS  MESENCHYMAL STEM-CELLS  INSULIN-RESISTANCE  LIPOPROTEIN METABOLISM  OBETICHOLIC ACID  RENAL-FIBROSIS  RECEPTOR-ALPHA  MOUSE MODEL  ER STRESS  
Artemicapillasins A-N, cytotoxic coumaric acid analogues against hepatic stellate cell LX2 from Artemisia capillaris (Yin-Chen) 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 117, 页码: 105441
作者:  Gao,Zhen;  Huang,Xiao-Yan;  Geng,Chang-An;  Li,Tian-Ze;  Chen,Ji-Jun
浏览  |  Adobe PDF(1872Kb)  |  收藏  |  浏览/下载:276/77  |  提交时间:2022/04/02
Artemisia capillaris  Coumaric acid analogues  Antihepatic fibrosis effects  HSC-LX2  Extracellular matrix  TRADITIONAL CHINESE HERB  ACTIVE CONSTITUENTS  LIVER FIBROSIS  
Synthesis and anti-fibrotic effects of santamarin derivatives as cytotoxic agents against hepatic stellate cell line LX2 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 41, 页码: 127994
作者:  Wang,Jin-Ping;  Li,Tian-Ze;  Huang,Xiao-Yan;  Geng,Chang-An;  Shen,Cheng;  Sun,Jin-Jin;  Xue,Dong;  Chen,Ji-Jun
浏览  |  Adobe PDF(567Kb)  |  收藏  |  浏览/下载:214/57  |  提交时间:2022/04/02
Santamarin derivatives  Anti-fibrotic effects  HSC-LX2  Extracellular matrix  NF-KAPPA-B  SESQUITERPENE LACTONES  LIVER FIBROSIS  STRUCTURE REQUIREMENT  BAY LEAF  ACTIVATION  
Pharmacological effects of indole alkaloids from Alstonia scholaris (L.) R. Br. on pulmonary fibrosis in vivo 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2021, 卷号: 267, 页码: 113506
作者:  Zhao,Yun-Li;  Pu,Shi-Biao;  Qi,Yan;  Wu,Bai-Fen;  Shang,Jian-Hua;  Liu,Ya-Ping;  Hu,Di;  Luo,Xiao-Dong
浏览  |  Adobe PDF(9993Kb)  |  收藏  |  浏览/下载:222/62  |  提交时间:2022/04/02
Alstonia scholaris  Indole alkaloids  Pulmonary fibrosis  Picrinine  Vallesamine  Scholaricine  19-Epischolaricine  FLIGHT MASS-SPECTROMETRY  ACUTE LUNG INJURY  AIRWAY INFLAMMATION  OXIDATIVE STRESS  BARK EXTRACTS  LEAVES  CONSTITUENTS  COLLAGEN  LEAF  KL-6  
Petchiether A attenuates obstructive nephropathy by suppressing TGF-ss/Smad3 and NF-kappa B signalling 期刊论文
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2019, 卷号: 23, 期号: 8, 页码: 5576-5587
作者:  You, Yong-Ke;  Luo, Qi;  Wu, Wei-Feng;  Zhang, Jiao-Jiao;  Zhu, Hong-Jian;  Lao, Lixing;  Lan, Hui Y.;  Chen, Hai-Yong;  Cheng, Yong-Xian
浏览  |  Adobe PDF(3491Kb)  |  收藏  |  浏览/下载:317/67  |  提交时间:2019/10/14
fibrosis  NF-kappa B  obstructive nephropathy  petchiether A  TGF-ss/Smad3  
Hepatoprotective steroids from roots of Cynanchum otophyllum 期刊论文
FITOTERAPIA, 2019, 卷号: 136, 页码: 7
作者:  Dong, Jinrun;  Peng, Xingrong;  Lu, Shuangyang;  Zhou, Lin;  Qiu, Minghua
浏览  |  Adobe PDF(466Kb)  |  收藏  |  浏览/下载:377/90  |  提交时间:2019/08/19
Cynanchum otophyllum  Asclepiadaceae  Steriods  Anti-liver fibrosis activity  
Renoprotective meroterpenoids from the fungus Ganoderma cochlear 期刊论文
FITOTERAPIA, 2019, 卷号: 132, 页码: 88-93
作者:  Wang, Xin-Long;  Wu, Ze-Hong;  Di, Lei;  Zhou, Feng-Jiao;  Yan, Yong-Ming;  Cheng, Yong-Xian
浏览  |  Adobe PDF(827Kb)  |  收藏  |  浏览/下载:371/89  |  提交时间:2019/03/18
Ganoderma cochlear  Meroterpenoids  ECD calculations  Renal fibrosis  
Lanostane-type triterpenoids from the fruiting bodies of Ganoderma applanatum 期刊论文
PHYTOCHEMISTRY, 2019, 卷号: 157, 页码: 103-110
作者:  Peng, XingRong;  Li, Lei;  Dong, JinRun;  Lu, ShuangYang;  Lu, Jing;  Li, XiaoNian;  Zhou, Lin;  Qiu, MingHua
浏览  |  Adobe PDF(830Kb)  |  收藏  |  浏览/下载:1049/303  |  提交时间:2019/01/22
Ganoderma applanatum (Pers.) Pat.  Ganodermataceae  Lanostane-type triterpenoid  X-ray crystallographic analyses  Anti-liver fibrosis activity