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Rubiginosin B selectively inhibits Treg cell differentiation and enhances anti-tumor immune responses by targeting calcineurin-NFAT signaling pathway 期刊论文
PHYTOMEDICINE, 2023, 卷号: 116, 页码: 154898
作者:  Geng,Chang-An;  Chen,Feng-Yang;  Zheng,Jing-Bin;  Liao,Ping;  Li,Tian-Ze;  Zhang,Xue-Mei;  Chen,Xin;  Chen,Ji-Jun
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Rubiginosin B (RGB)  CD4(+)Foxp3(+) regulatory T cells (Tregs)  Calcineurin  Nuclear factor of activated T cells (NFAT)  Tumor microenvironment  Rhododendron brachypodum  REGULATORY T-CELLS  RHODODENDRON  IMMUNOSUPPRESSION  DERIVATIVES  INDUCTION  EXPANSION  RAPAMYCIN  
Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Small-Molecule Drugs in Immunotherapy 期刊论文
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:  Hao,Xuanrun;  Chen,Zhongliang;  Li,Haining;  Wei,Minqin;  Zuo,Zhili;  Su,Qing
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Cancer immunotherapy  inhibitors  Pd-1/Pd-L1 inhibitor  IDO inhibitor  STING agonists  ROR gamma t agonists  TGF  beta inhibitors  INDOLEAMINE 2,3-DIOXYGENASE  SIGNALING INHIBITOR  DENDRITIC CELLS  GROWTH  TUMOR  PATHWAY  PEMBROLIZUMAB  RECEPTORS  DISCOVERY  VADIMEZAN  
A natural acylphloroglucinol triggered antiproliferative possessions in HEL cells by impeding STAT3 signaling and attenuating angiogenesis in transgenic zebrafish model 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 141, 页码: 111877
作者:  Hu,Mi;  Varier,Krishnapriya M.;  Li,Zhicao;  Qin,Xujie;  Rao,Qing;  Song,Jingrui;  Hu,Anling;  Hang,Yubing;  Yuan,Chunmao;  Gajendran,Babu;  Shu,Liping;  Wen,Min;  Li,Yanmei;  Liu,Haiyang
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Acylphloroglucinol  HEL cells  Intrinsic apoptotic pathway  Anti-angiogenesis  STAT3  Flk-1  CALLISTEMON-CITRINUS  TUMOR ANGIOGENESIS  DNA  DERIVATIVES  ANTICANCER  APOPTOSIS  ACTIVATION  INHIBITORS  TARGETS  LEAVES  
Characterization of Proapoptotic Compounds from the Bark of Garcinia oblongifolia 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2014, 卷号: 77, 期号: 5, 页码: 1111-1116
作者:  Feng, Chao;  Huang, Sheng-Xiong;  Gao, Xue-Mei;  Xu, Hong-Xi;  Luo, Kathy Qian;  Xu,HX (reprint author),Shanghai Univ Tradit Chinese Med,Sch Pharm,Shanghai 201203,Peoples R China.;  xuhongxi88@gmail.com;  kluo@ntu.edu.sg
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Anticancer Drug Screen  Inhibits Tumor-growth  Hela-cells  Apoptosis  Activation  Death  Resistance  Dynamics  Lines  Her2  
Trichothecin Induces Cell Death in NF-kappa B Constitutively Activated Human Cancer Cells via Inhibition of IKK beta Phosphorylation 期刊论文
PLOS ONE, 2013, 卷号: 8, 期号: 8, 页码: e71333
作者:  Su, Jia;  Zhao, Peiji;  Kong, Lingmei;  Li, Xingyao;  Yan, Juming;  Zeng, Ying;  Li, Yan
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Colitis-associated Cancer  Multiple-myeloma Cells  P65 Phosphorylation  Endophytic Fungus  Kinase-activity  Tumor-growth  In-vitro  Pathway  Apoptosis  Inflammation  
Chemical constituents of Allophylus longipes 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2012, 卷号: 10, 期号: 1, 页码: 36-39
作者:  Zhang Xiang-Yun;  Cai Xiang-Hai;  Luo Xiao-Dong
Adobe PDF(265Kb)  |  收藏  |  浏览/下载：443/158  |  提交时间：2012/06/07
Cancer Therapy  Synthetic Lethal  Traditional Chinese Medicine  Xpc  Ercc6  Csb  Traditional Chinese-medicine  Pigmentosum Group-c  Induced Dna-damage  Xeroderma-pigmentosum  Tumor-cells  Cockayne-syndrome  Mammalian-cells  Essential Oil  Cancer  Chenopodium  
Pharicin A, a novel natural ent-kaurene diterpenoid, induces mitotic arrest and mitotic catastrophe of cancer cells by interfering with BubR1 function 期刊论文
CELL CYCLE, 2010, 卷号: 9, 期号: 14, 页码: 2897-2907
作者:  Xu, Han-Zhang;  Huang, Ying;  Wu, Ying-Li;  Zhao, Yong;  Xiao, Wei-Lie;  Lin, Qi-Shan;  Sun, Han-Dong;  Dai, Wei;  Chen, Guo-Qiang
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Pharicin a  Mitotic Arrest  Leukemia  Tumor Cells  Spindle Checkpoint  
Three New Triterpenoids Containing Four-Membered Ring from the Fruiting Body of Ganoderma sinense 期刊论文
ORGANIC LETTERS, 2010, 卷号: 12, 期号: 8, 页码: 1656-1659
作者:  Wang, Cui-Fang;  Liu, Jie-Qing;  Yan, Yu-Xin;  Chen, Jian-Chao;  Lu, Yang;  Guo, Yong-Hui;  Qiu, Ming-Hua
Adobe PDF(188Kb)  |  收藏  |  浏览/下载：405/147  |  提交时间：2012/03/21
Tumor-cells  Lucidum  Cytotoxicity  Fornicatum  Spores  
4-arylcoumarin inhibits immediate-type allergy 期刊论文
FOOD AND AGRICULTURAL IMMUNOLOGY, 2007, 卷号: 18, 期号: 3-4, 页码: 203-211
作者:  Taechowisan, Thongchai;  Lu, Chunhua;  Shen, Yuemao;  Lumyong, Saisamorn
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4-arylcoumarins  Immediate-type Allergic Reaction  Mast Cells  Tumor Necrosis Factor-alpha  Interleukin-6