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Synthesis and biological evaluation of novel 3-benzylcoumarin-imidazolium salts 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2020, 卷号: 30, 期号: 4, 页码: 6
作者:  Wang, Xue-Quan;  Chen, Xue-Bing;  Ye, Ping-Ting;  Yang, Zhi-Xin;  Bai, Meng-Jiao;  Duan, Su-Yue;  Li, Yan;  Yang, Xiao-Dong
收藏  |  浏览/下载：181/0  |  提交时间：2020/03/18
3-Benzylcoumarin  Imidazolium salts  Biological evaluation  Cytotoxic activity  Structure-activity relationships  
Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3299-3306
作者:  Chen, Si-Yue;  Geng, Chang-An;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Yang, Xiao-Tong;  Su, Li-Hua;  He, Xiao-Feng;  Li, Tian-Ze;  Deng, Zhen-Tao;  Gao, Zhen;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(1837Kb)  |  收藏  |  浏览/下载：197/35  |  提交时间：2019/09/10
Gastrodia elata  Polybenzyls  Melatonin receptors  Structure-activity relationships  Docking study  
Synthesis and antitumor activity of novel steroidal imidazolium salt derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2019, 卷号: 168, 页码: 232-252
作者:  Deng, Guogang;  Zhou, Bei;  Wang, Jing;  Chen, Zhuo;  Gong, Liang;  Gong, Yaxiao;  Wu, Dongmei;  Li, Yan;  Zhang, Hongbin;  Yang, Xiaodong
浏览  |  Adobe PDF(1727Kb)  |  收藏  |  浏览/下载：251/37  |  提交时间：2019/07/29
Diosgenin  Cholesterol  Dehydroepiandrosterone  Imidazolium salt  Antitumor activities  Structure-activity relationships  
Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists 期刊论文
BIOORGANIC CHEMISTRY, 2019, 卷号: 84, 页码: 285-294
作者:  Chen, Duo-zhi;  Yang, Bi-juan;  He, Xiao-li;  Fan, Shi-rui;  Cai, Jie-yun;  Jing, Chen-xu;  Zhang, Heng;  Zhang, Yu;  Li, Lin;  Hao, Xiao-jiang
浏览  |  Adobe PDF(3047Kb)  |  收藏  |  浏览/下载：312/37  |  提交时间：2019/03/18
Wnt/beta-catenin signalling pathway agonist  Phenanthridine derivatives  Structural optimization  Structure-activity relationships (SARs)  
Synthesis and antitumor activity of biotinylated camptothecin derivatives as potent cytotoxic agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 29, 期号: 2, 页码: 234-237
作者:  Zi, Cheng-Ting;  Yang, Liu;  Xu, Feng-Qing;  Dong, Fa-Wu;  Ma, Rui-Jing;  Li, Yan;  Zhou, Jun;  Ding, Zhong-Tao;  Jiang, Zi-Hua;  Hu, Jiang-Miao
浏览  |  Adobe PDF(500Kb)  |  收藏  |  浏览/下载：431/190  |  提交时间：2019/03/18
Biodnylated Camptothecin Derivatives  Anticancer Activity  Synthesis  Click Chemistry  Structure-activity Relationships (Sars)  
Anti-hepatitis B virus effects of the traditional Chinese herb Arteinisia capillaris and its active enynes 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2018, 卷号: 224, 页码: 283-289
作者:  Geng, Chang-An;  Yang, Tong-Hua;  Huang, Xiao-Yan;  Yang, Jing;  Ma, Yun-Bao;  Li, Tian-Ze;  Zhang, Xue-Mei;  Chen, Ji-Jun
收藏  |  浏览/下载：263/0  |  提交时间：2018/09/27
Artemisia capillaris  Enynes  Anti-HBV activity  Structure-activity relationships  
Synthesis of Fucosylated Chondroitin Sulfate Glycoclusters: A Robust Route to New Anticoagulant Agents 期刊论文
CHEMISTRY-A EUROPEAN JOURNAL, 2018, 卷号: 24, 期号: 7, 页码: 1694-1700
作者:  Zhang, Xiao;  Yao, Wang;  Xu, Xiaojiang;  Sun, Huifang;  Zhao, Jinhua;  Meng, Xiangbao;  Wu, Mingyi;  Li, Zhongjun
浏览  |  Adobe PDF(1719Kb)  |  收藏  |  浏览/下载：194/51  |  提交时间：2018/05/08
Anticoagulants  Drug Discovery  Glycoconjugates  Structure-activity Relationships  Synthesis Design  
Bioactivity-guided synthesis of gramine derivatives as new MT1 and 5-HT1A receptors agonists 期刊论文
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2017, 卷号: 19, 期号: 6, 页码: 610-622
作者:  Yin, Xiu-Juan;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Geng, Chang-An;  Li, Tian-Ze;  Chen, Xing-Long;  Yang, Tong-Hua;  Zhou, Jun;  Zhang, Xue-Mei;  Chen, Ji-Jun
浏览  |  Adobe PDF(2718Kb)  |  收藏  |  浏览/下载：335/60  |  提交时间：2017/07/10
Gramine  Melatonin Receptor  5-hydroxy-tryptamine Receptor  Agonistic Activity  Structure-activity Relationships  
Synthesis of erythrocentaurin derivatives as a new class of hepatitis B virus inhibitors 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 7, 页码: 1568-1571
作者:  Geng, Chang-An;  Huang, Xiao-Yan;  Ma, Yun-Bao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
浏览  |  Adobe PDF(1409Kb)  |  收藏  |  浏览/下载：307/113  |  提交时间：2015/06/29
Erythrocentaurin  Anti-hbv Activity  Structure-activity Relationships  
Isolation, synthesis and anti-hepatitis B virus evaluation of p-hydroxyacetophenone derivatives from Artemisia capillaris 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 卷号: 25, 期号: 7, 页码: 1509-1514
作者:  Zhao, Yong;  Geng, Chang-An;  Chen, Hao;  Ma, Yun-Bao;  Huang, Xiao-Yan;  Cao, Tuan-Wu;  He, Kang;  Wang, Hao;  Zhang, Xue-Mei;  Chen, Ji-Jun;  Chen,JJ (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Kunming 650201,Peoples R China.;  chenjj@mail.kib.ac.cn
浏览  |  Adobe PDF(2494Kb)  |  收藏  |  浏览/下载：312/96  |  提交时间：2015/06/29
Artemisia Capillaris  P-hydroxyacetophenone Derivatives  Anti-hbv Activity  Structure-activity Relationships