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High throughput-screening of native herbal compounds identifies taccaoside A as a cytotoxic compound that mediates RAS signaling in cancer stem cells 期刊论文
PHYTOMEDICINE, 2023, 卷号: 108, 页码: 154492
作者:  Yang,Dong;  Dai,Zhi;  Zhu,Peifeng;  Wang,Gan;  Sun,Bin;  Li,Shirong;  Hao,Junjun;  Wang,Yifen;  Liu,Yaping;  Yu,Shuaishuai;  Lai,Ren;  Luo,Xiao-Dong;  Zhao,Xudong
浏览  |  Adobe PDF(6987Kb)  |  收藏  |  浏览/下载：153/23  |  提交时间：2024/07/17
Natural product  Furostanol saponin  Taccaoside A  Cancer stem cell  RAS  STEROIDAL SAPONINS  NATURAL-PRODUCTS  PI3K/AKT  PROLIFERATION  MAINTENANCE  STATISTICS  MAPK/ERK  
RUNX1 knockdown induced apoptosis and impaired EMT in high-grade serous ovarian cancer cells 期刊论文
JOURNAL OF TRANSLATIONAL MEDICINE, 2023, 卷号: 21, 期号: 1, 页码: 886
作者:  Chen,Yuanzhi;  He,Zhicheng;  Yang,Shuting;  Chen,Cheng;  Xiong,Wenyong;  He,Yingying;  Liu,Shubai
浏览  |  Adobe PDF(4466Kb)  |  收藏  |  浏览/下载：165/26  |  提交时间：2024/05/09
Runt-related transcription factor 1 (RUNX1)  High-grade serous ovarian carcinoma (HGSOC)  Apoptosis  EMT  Clinical therapeutic target  EPITHELIAL-MESENCHYMAL TRANSITIONS  HEPATOCELLULAR-CARCINOMA  TRANSCRIPTION FACTOR  TP53 MUTATIONS  UP-REGULATION  TUMOR-GROWTH  MIGRATION  PROLIFERATION  INVASION  FOXO1  
Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect 期刊论文
FRONTIERS IN PHARMACOLOGY, 2023, 卷号: 14, 页码: 1219362
作者:  Guo,Xiuping;  Li,Rui;  Cui,Jinjin;  Hu,Chujuan;  Yu,Haoyang;  Ren,Ling;  Cheng,Yangyang;  Jiang,Jiandong;  Ding,Xiao;  Wang,Lulu
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Erigeron Breviscapus Injection  Dengzhanxixin  Erigeron Breviscapus (Vant  ) Hand  -mazz  Colorectal Cancer  Necroptosis  Drug Resistance  Tumor-necrosis-factor  Colorectal-cancer  Natural Compounds  Scutellarin  Apoptosis  Proliferation  Macrophages  Migration  Invasion  Therapy  
Association of sirtuins (SIRT1-7) with lung and intestinal diseases 期刊论文
MOLECULAR AND CELLULAR BIOCHEMISTRY, 2022, 卷号: 477, 期号: 11, 页码: 2539-2552
作者:  Chen, Yuhan;  Zhou, Di;  Feng, Yuan;  Li, Bingxin;  Cui, Yong;  Chen, Gang;  Li, Ning
浏览  |  Adobe PDF(765Kb)  |  收藏  |  浏览/下载：187/43  |  提交时间：2024/04/30
Sirtuins  Lung-intestinal axis  Inflammation  Tumors  MicroRNAs  ENDOPLASMIC-RETICULUM STRESS  EPITHELIAL-MESENCHYMAL TRANSITION  CANCER CELLS  ULCERATIVE-COLITIS  COLORECTAL-CANCER  DOWN-REGULATION  PROLIFERATION  SUPPRESSES  ACTIVATION  APOPTOSIS  
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels 期刊论文
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 1081697
作者:  Su, Deyuan;  Gong, Ye;  Li, Songyu;  Yang, Jian;  Nian, Yin
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Cyclovirobuxine D  Ca(v)3  2  Ca(v)2  Buxus microphylla  analgesic effects  ROOT GANGLION NEURONS  CALCIUM-CHANNELS  CELL-PROLIFERATION  PACLITAXEL  RAT  RECEPTOR  GENE  EXPRESSION  APOPTOSIS  CURRENTS  
Noncoding RNAs and RNA-binding proteins in diabetic wound healing 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2021, 卷号: 50, 页码: 128311
作者:  Li,Xue;  Li,Ning;  Li,Bingxin;  Feng,Yuan;  Zhou,Di;  Chen,Gang
收藏  |  浏览/下载：167/0  |  提交时间：2022/04/02
ncRNAs  lncRNAs  circRNAs  RNA-binding protein  Modulating drugs  Diabetic  Wound healing  ENDOTHELIAL-CELLS  OXIDATIVE STRESS  PROLIFERATION  APOPTOSIS  INFLAMMATION  DYSFUNCTION  EXPRESSION  MIGRATION  CANCER  INJURY  
Monoterpene Indole Alkaloids with Ca(v)3.1 T-Type Calcium Channel Inhibitory Activity from Catharanthus roseus 期刊论文
MOLECULES, 2021, 卷号: 26, 期号: 21, 页码: 6516
作者:  Deng,Zhen-Tao;  Li,Wen-Yan;  Wang,Lei;  Zhou,Zhi-Ping;  Wu,Xing-De;  Ding,Zhong-Tao;  Zhao,Qin-Shi
浏览  |  Adobe PDF(2354Kb)  |  收藏  |  浏览/下载：288/89  |  提交时间：2022/04/02
Catharanthus roseus  monoterpene indole alkaloid  catharanosine A  Ca(v)3  1 low voltage-gated calcium channel (LVGCC)  VINCA ALKALOIDS  CELL-PROLIFERATION  N-OXIDE  SARPAGINE  BIOSYNTHESIS  VINORELBINE  VINBLASTINE  MECHANISM  ROOTS  BASES  
Traditional Chinese medicine compound, Bu Sheng Hui Yang Fang, promotes the proliferation of lymphocytes in the immunosuppressed mice potentially by upregulating IL-4 signaling 期刊论文
BIOMEDICINE & PHARMACOTHERAPY, 2021, 卷号: 134, 页码: 111107
作者:  Wang,Yajie;  Tan,Jiabin;  Hu,Peng;  Pei,Qiang;  Wen,Yan;  Ma,Wenqing;  Shi,Keqian;  Li,Zengzheng;  Li,Huiyuan;  Cheng,Fengyu;  Gu,Xuezhong;  Yao,Xiangmei;  Man,Yan;  Zhao,Renbin;  Feng,Shuai;  Ding,Xiao;  Yang,Tonghua
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Bu Shen Hui Yang Fang (BSHY)  Immunoenhancement  Lymphocytes  Proliferation  Cytokine  IL-4  ACUTE MYELOID-LEUKEMIA  IMMUNE-SYSTEM  CANCER  CELLS  IMMUNOSURVEILLANCE  EXPRESSION  
The F-box protein MIO1/SLB1 regulates organ size and leaf movement in Medicago truncatula 期刊论文
JOURNAL OF EXPERIMENTAL BOTANY, 2021, 卷号: 72, 期号: 8, 页码: 2995-3011
作者:  Zhou,Shaoli;  Yang,Tianquan;  Mao,Yawen;  Liu,Ye;  Guo,Shiqi;  Wang,Ruoruo;  Fangyue,Genwang;  He,Liangliang;  Zhao,Baolin;  Bai,Quanzi;  Li,Youhan;  Zhang,Xiaojia;  Wang,Dongfa;  Wang,Chaoqun;  Wu,Qing;  Yang,Yuanfan;  Liu,Yu;  Tadege,Million;  Chen,Jianghua
收藏  |  浏览/下载：211/0  |  提交时间：2022/04/02
BIG SEEDS1 (BS1)  F-box protein  MINI ORGAN1 (MIO1)/SMALL LEAF AND BUSHY1 (SLB1)  SCF E3 ligase  proteasome-mediated degradation  organ size  pulvinus  CELL-PROLIFERATION  ARABIDOPSIS-THALIANA  TRANSCRIPTION FACTOR  SEED SIZE  GROWTH  GENE  IDENTIFICATION  KINASES  CYCLE  E2FB  
Genome-Wide Identification and Characterization of BrrTCP Transcription Factorsin Brassica rapa ssp rapa 期刊论文
FRONTIERS IN PLANT SCIENCE, 2017, 卷号: 8, 期号: 1, 页码: 1588
作者:  Du, Jiancan;  Hu, Simin;  Yu, Qin;  Wang, Chongde;  Yang, Yunqiang;  Sun, Hang;  Yang, Yongping;  Sun, Xudong
浏览  |  Adobe PDF(4668Kb)  |  收藏  |  浏览/下载：262/46  |  提交时间：2017/10/23
Tcp  Transcription Factors  Expression Analysis  Turnip  Cell Proliferation