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Metabolomics Reveals Gut Microbiota Contribute to PPARα Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023, 卷号: 22, 期号: 7, 页码: 2327-2338
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：48/11  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Metabolomics Reveals Gut Microbiota Contribute to PPAR & alpha; Deficiency-Induced Alcoholic Liver Injury 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2023
作者:  Zhang,Ting;  Bao,Lijuan;  Zhao,Qi;  Wu,Zhanxuan E. E.;  Dai,Manyun;  Rao,Qianru;  Li,Fei
浏览  |  Adobe PDF(9616Kb)  |  收藏  |  浏览/下载：55/15  |  提交时间：2024/07/10
metabolomics  alcohol-induced liver injury  gut microbiota  PPAR & alpha  AROMATIC-AMINO-ACIDS  LIPID-METABOLISM  FED MICE  MODULATION  DISEASE  AXIS  OLEOYLETHANOLAMIDE  AGONIST  OBESITY  DEATH  
Identification of 3H-benzo[b] [1,4] diazepine derivatives as PPARα agonists by in silico studies and biochemical evaluation 期刊论文
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2023, 页码: 2256867
作者:  Li,Yue;  Lv,Mengjia;  Shen,Meiling;  Gu,Xi;  Zhang,Li;  Liu,Xingyong;  Chen,Jing;  Gong,Likun;  Zuo,Zhili
浏览  |  Adobe PDF(3338Kb)  |  收藏  |  浏览/下载：31/2  |  提交时间：2024/07/31
NAFLD  PPAR alpha agonist  virtual screening  biochemical evaluation  FATTY-ACID OXIDATION  GROMACS  
Metabolomics reveals the role of PPAR alpha in Tripterygium Wilfordii-induced liver injury 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2022, 卷号: 289, 页码: 16
作者:  Dai, Manyun;  Peng, Wan;  Zhang, Ting;  Zhao, Qi;  Ma, Xiaofang;  Cheng, Yan;  Wang, Chunyan;  Li, Fei
收藏  |  浏览/下载：390/0  |  提交时间：2022/07/15
Tripterygium wilfordii  Liver injury  PPAR alpha  IL6-STAT3  Metabolomics  
The Protective Roles of PPAR alpha Activation in Triptolide-Induced Liver Injury 期刊论文
TOXICOLOGICAL SCIENCES, 2019, 卷号: 171, 期号: 1, 页码: 1-12
作者:  Hu, Dan-Dan;  Zhao, Qi;  Cheng, Yan;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Qu, Yan;  Li, Xian;  Tang, Ying-Mei;  Bao, Wei-Min;  Yang, Jin-Hui;  Jiang, Tao;  Hu, Jia-Peng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(1740Kb)  |  收藏  |  浏览/下载：313/60  |  提交时间：2020/03/26
liver injury  metabolomics  PPAR alpha  acylcarnitines  
Basal PPAR alpha inhibits bile acid metabolism adaptation in chronic cholestatic model induced by alpha-naphthylisothiocyanate 期刊论文
TOXICOLOGY LETTERS, 2019, 卷号: 300, 页码: 31-39
作者:  Hua, Huiying;  Dai, Manyun;  Luo, Yishuang;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Xu, Liping;  Zhang, Haoyue;  Tang, Zhiyuan;  Chang, Liming;  Liu, Aiming;  Yang, Julin
浏览  |  Adobe PDF(3156Kb)  |  收藏  |  浏览/下载：353/46  |  提交时间：2018/12/18
PPAR alpha  FXR pathway  Alpha-naphthylisothiocyanate  Chronic cholestasis  
PPAR alpha Mediates the Hepatoprotective Effects of Nutmeg 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 5, 页码: 1887-1897
作者:  Yang, Xiao-Nan;  Liu, Xue-Mei;  Fang, Jian-He;  Zhu, Xu;  Yang, Xiu-Wei;  Xiao, Xue-Rong;  Huang, Jian-Feng;  Gonzalez, Frank J.;  Li, Fei
浏览  |  Adobe PDF(2643Kb)  |  收藏  |  浏览/下载：303/91  |  提交时间：2018/07/02
Nutmeg  Hepatoprotective Activity  Metabolomics  Myrislignan  Ppar Alpha  
Targeted Metabolomics Reveals a Protective Role for Basal PPAR alpha in Cholestasis Induced by alpha-Naphthylisothiocyanate 期刊论文
JOURNAL OF PROTEOME RESEARCH, 2018, 卷号: 17, 期号: 4, 页码: 1500-1508
作者:  Dai, Manyun;  Hua, Huiying;  Lin, Hante;  Xu, Gangming;  Hu, Xiaowei;  Li, Fei;  Gonzalez, Frank J.;  Liu, Aiming;  Yang, Julin
浏览  |  Adobe PDF(2087Kb)  |  收藏  |  浏览/下载：283/64  |  提交时间：2018/05/08
Ppar Alpha  Nf-kappa b  Stat3  Alpha-naphthylisothiocyanate  Cholestasis