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Development of actein derivatives as potent anti-triple negative breast cancer agents 期刊论文
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2023, 卷号: 89, 页码: 129307
作者:  Zhang,Honglin;  Chen,Yiyan;  Huang,Songwen;  Xiao,Wen-Wen;  Qiu,Ming-Hua;  Shao,Li-Dong;  Chen,Chuan-Huizi;  Li,Dashan
浏览  |  Adobe PDF(1187Kb)  |  收藏  |  浏览/下载:37/9  |  提交时间:2024/07/22
Actein  Modification  Triple negative breast cancer  Structure-activity relationships  Mechanism  GROWTH-INHIBITORY ACTIVITY  BLACK COHOSH  EXTRACTS  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
浏览  |  Adobe PDF(5040Kb)  |  收藏  |  浏览/下载:46/10  |  提交时间:2024/07/22
Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:  Munikishore,Rachakunta;  Liu,Rui;  Zhang,Shuqun;  Zhao,Qin-Shi;  Nian,Yin;  Zuo,Zhili
浏览  |  Adobe PDF(5035Kb)  |  收藏  |  浏览/下载:49/9  |  提交时间:2024/07/22
Buxus alkaloid  Structural modification  T -type calcium channel  Analgesic activity  Docking analysis  Structure -activity relationship study  BUXOZINE-C  SEMPERVIRENS  RING  CONSTITUTION  
20-去氧巨大戟醇酯衍生物合成及其构效关系研究 学位论文
: 中国科学院大学, 2022
作者:  张翠珊
Adobe PDF(3951Kb)  |  收藏  |  浏览/下载:19/0  |  提交时间:2024/05/14
20-去氧巨大戟醇酯,自噬,结构修饰,构效关系  20-Deoxyingenane esters, Autophagy, Structural modification, SAR  
拟南芥和蓖麻种子特异表达基因的表观调控研究 学位论文
: 中国科学院大学, 2022
作者:  吴迪
Adobe PDF(7846Kb)  |  收藏  |  浏览/下载:49/0  |  提交时间:2024/05/14
拟南芥,蓖麻,种子特异基因,DNA甲基化谷,组蛋白修饰  Arabidopsis, Castor bean, Seed specific genes, DNA methylation valley, Histone modification  
海菜花化学成分研究和Telekin的结构改造 学位论文
: 中国科学院大学, 2022
作者:  曾政权
Adobe PDF(4997Kb)  |  收藏  |  浏览/下载:60/0  |  提交时间:2024/05/14
天然产物、海菜花、天名精、倍半萜内酯、结构修饰  Natural Products, Ottelia acuminata, Carpesium abrotanoides L., Sesquiterpene lactone, Structural modification  
Review on factors affecting coffee volatiles: from seed to cup 期刊论文
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2022, 卷号: 102, 期号: 4, 页码: 1341-1352
作者:  Wang,Xiaoyuan;  Wang,Yanbing;  Hu,Guilin;  Hong,Defu;  Guo,Tieying;  Li,Jinhong;  Li,Zhongrong;  Qiu,Minghua
浏览  |  Adobe PDF(1947Kb)  |  收藏  |  浏览/下载:160/30  |  提交时间:2022/04/02
aroma modification  controlled fermentation  superheated steam (SHS)  cold brew  coffee omics  STARTER CULTURES  AROMA COMPOUNDS  ROASTED COFFEE  ARABICA COFFEE  FERMENTATION  QUALITY  FLAVOR  BEANS  EXTRACTION  STORAGE  
三类活性天然萜类化合物的化学合成及结构修饰研究 学位论文
: 中国科学院大学, 2022
作者:  颜秉超
Adobe PDF(5191Kb)  |  收藏  |  浏览/下载:12/0  |  提交时间:2024/05/14
萜类化合物  terpenoids, structural modification, immunosuppression, lysosomal biosynthesis, chemical synthesis  结构修饰  免疫抑制  溶酶体生成  化学合成  
Synthesis of nigranoic acid and manwuweizic acid derivatives as HDAC inhibitors and anti-inflammatory agents 期刊论文
BIOORGANIC CHEMISTRY, 2021, 卷号: 109, 页码: 104728
作者:  Ni,Dong-Xuan;  Wang,Qi;  Li,Yi-Ming;  Cui,Yi-Man;  Shen,Tian-Ze;  Li,Xiao-Li;  Sun,Han-Dong;  Zhang,Xing-Jie;  Zhang,Ruihan;  Xiao,Wei-Lie
收藏  |  浏览/下载:93/0  |  提交时间:2022/04/02
Natural products modification  HDAC inhibition  Inflammasome  Triterpenoid  SCHISANDRA-PROPINQUA  TRITERPENOIDS  MECHANISM  INJURY  
Oligosaccharides from depolymerized fucosylated glycosaminoglycan: Structures and minimum size for intrinsic factor Xase complex inhibition 期刊论文
JOURNAL OF BIOLOGICAL CHEMISTRY, 2018, 卷号: 293, 期号: 36, 页码: 14089-14099
作者:  Yin, Ronghua;  Zhou, Lutan;  Gao, Na;  Li, Zi;  Zhao, Longyan;  Shang, Feineng;  Wu, Mingyi;  Zhao, Jinhua
浏览  |  Adobe PDF(1313Kb)  |  收藏  |  浏览/下载:272/50  |  提交时间:2018/10/07
Natural Product  Carbohydrate Chemistry  Carbohydrate Structure  Chemical Modification  Drug Discovery  Oligosaccharide  Thrombosis