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Natural product Eriocalyxin B suppressed triple negative breast cancer metastasis both in vitro and in vivo 期刊论文
BIOCHEMICAL PHARMACOLOGY, 2023, 卷号: 210, 页码: 115491
作者:  Gou,Leilei;  Yue,Grace Gar-Lee;  Lee,Julia Kin -Ming;  Puno,Pema Tenzin;  Lau,Clara Bik-San
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Breast cancer  Metastasis  Natural products  Eriocalyxin B  Cancer recurrence  Cancer stem cells  Gut microbiome  NF-KAPPA-B  STEM-CELLS  MOLECULAR-MECHANISMS  EXTRACELLULAR-MATRIX  TUMOR-GROWTH  APOPTOSIS  ANGIOGENESIS  PROGRESSION  CARCINOMA  LEUKEMIA  
Structurally Diverse Diterpenoids from lsodon scoparius and Their Bioactivity 期刊论文
JOURNAL OF NATURAL PRODUCTS, 2017, 卷号: 80, 期号: 7, 页码: 2026-2036
作者:  Jiang, Hua-Yi;  Wang, Wei-Guang;  Tang, Jian-Wei;  Liu, Miao;  Li, Xing-Ren;  Hu, Kun;  Du, Xue;  Li, Xiao-Nian;  Zhang, Hong-Bin;  Pu, Jian-Xin;  Sun, Han-Dong
浏览  |  Adobe PDF(1786Kb)  |  收藏  |  浏览/下载：528/89  |  提交时间：2017/10/23
Ent-kaurane Diterpenoids  Isodon-scoparius  Cytotoxic Diterpenoids  Abietane Diterpenoids  Eriocalyxin-b  Derivatives  Laxiflora  Growth  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
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Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
Bisleuconothine A和Eriocalyxin B抗肿瘤作用机制研究 学位论文
, 昆明: 中国科学院大学, 2015
作者:  孔令梅
Adobe PDF(9659Kb)  |  收藏  |  浏览/下载：243/14  |  提交时间：2017/06/09
Wnt信号通路  Bisleuconothine a  抗肿瘤活性  Eriocalyxin b  Nf-κb信号通路  P50  
Eriocalyxin B-Induced Apoptosis in Pancreatic Adenocarcinoma Cells Through Thiol-Containing Antioxidant Systems and Downstream Signalling Pathways 期刊论文
CURRENT MOLECULAR MEDICINE, 2014, 卷号: 14, 期号: 5, 页码: 673-689
作者:  Li, L.;  Yue, G. G. L.;  Pu, J. X.;  Sun, H. D.;  Fung, K. P.;  Leung, P. C.;  Han, Q. B.;  Lau, C. B. S.;  Leung, P. S.;  Xu, JC (reprint author), Chinese Acad Sci, Kunming Inst Bot, Key Lab Plant Biodivers & Biogeog East Asia, Kunming 650201, Yunnan, Peoples R China.;  j.c.xu@cgiar.org;  kdhyde3@gmail.com
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Apoptosis  Eriocalyxin b  Pancreatic Cancer  Reactive Oxygen Species  Thiols  
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways 期刊论文
TOXICOLOGY AND APPLIED PHARMACOLOGY, 2012, 卷号: 262, 期号: 1, 页码: 80-90
作者:  Li, Lin;  Yue, Grace G. L.;  Lau, Clara B. S.;  Sun, Handong;  Fung, Kwok Pui;  Leung, Ping Chung;  Han, Quanbin;  Leung, Po Sing
浏览  |  Adobe PDF(2066Kb)  |  收藏  |  浏览/下载：372/70  |  提交时间：2014/04/02
Eriocalyxin b  Pancreatic Cancer  Apoptosis  Cell Cycle Arrest  P53  
Quick identification of apoptosis inducer from Isodon eriocalyx by a drug discovery platform composed of analytical high-speed counter-current chromatography and the fluorescence-based caspase-3 biosensor detection 期刊论文
TALANTA, 2010, 卷号: 82, 期号: 4, 页码: 1521-1527
作者:  Han, Quan-Bin;  Yu, Ting;  Lai, Fanny;  Zhou, Yan;  Feng, Chao;  Wang, Wei-Na;  Fu, Xiao-Hui;  Lau, Clara Bik-San;  Luo, Kathy Q.;  Xu, Hong-Xi;  Sun, Han-Dong;  Fung, Kwok-Pui;  Leung, Ping-Chung
Adobe PDF(487Kb)  |  收藏  |  浏览/下载：435/150  |  提交时间：2012/03/21
Analytical High-speed Counter-current Chromatography  Caspase-3 Biosensor  Isodon Eriocalyx  Apoptosis Inducer  Eriocalyxin b  
Gomisin M1、Eriocalyxin B及Przewalskin B的合成及生物活性研究 学位论文
, 昆明植物研究所: 中国科学院昆明植物研究所, 2009
刘靖平
Adobe PDF(1149Kb)  |  收藏  |  浏览/下载：441/25  |  提交时间：2011/10/25
Gomisin M1  Eriocalyxin b  Przewalskin b  联苯环辛二烯木脂素  抗hiv-1活性  抗肿瘤活性  全合成  
Synthesis and cytotoxicity of some new eriocalyxin B derivatives 期刊论文
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2007, 卷号: 42, 期号: 4, 页码: 494-502
作者:  Zhao, Yu;  Niu, Xue-Mei;  Qian, Li-Ping;  Liu, Ze-Yuan;  Zhao, Qin-Shi;  Sun, Han-Dong
Adobe PDF(329Kb)  |  收藏  |  浏览/下载：429/142  |  提交时间：2011/11/24
Eriocalyxin b  Synthesis  Cytotoxicity  Sar  
Eriocalyxin B induces apoptosis of t(8;21) leukemia cells through NF-kappa B and MAPK signaling pathways and triggers degradation of AML1-ETO oncoprotein in a caspase-3-dependent manner 期刊论文
CELL DEATH AND DIFFERENTIATION, 2007, 卷号: 14, 期号: 2, 页码: 306-317
作者:  Wang, L.;  Zhao, W. -L.;  Yan, J. -S.;  Liu, P.;  Sun, H. -P.;  Zhou, G. -B.;  Weng, Z. -Y.;  Wu, W. -L.;  Weng, X. -Q.;  Sun, X. -J.;  Chen, Z.;  Sun, H. -D.;  Chen, S. -J.
Adobe PDF(796Kb)  |  收藏  |  浏览/下载：756/99  |  提交时间：2012/10/12
Eriocalyxin b  Acute Myeloid Leukemia  Apoptosis  Nf-kappa b  Mapk  Aml1-eto