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ARL6IP1 mediates small-molecule-induced alleviation of Alzheimer pathology through FXR1-dependent BACE1 translation initiation 期刊论文
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2023, 卷号: 120, 期号: 22, 页码: e2220148120
作者:  Zhou,Gui-Feng;  Tang,Jing;  Ma,Yuan-Lin;  Fu,Xian;  Liu,Jun-Yan;  Yang,Ren-Zhi;  Zhang,Hong-Sheng;  Cai,Xiang-Hai;  Wang,Jing-Wen;  Xie,Xiao-Yong;  Song,Li;  Luo,Biao;  Chen,Jian;  Chen,Long;  Deng,Xiao-Juan;  Chen,Guo-Jun
浏览  |  Adobe PDF(6685Kb)  |  收藏  |  浏览/下载:110/18  |  提交时间:2024/05/09
conophylline  ARL6IP1  5'UTR  FXR1  BACE1 translation  AMYLOID PRECURSOR PROTEIN  A-BETA  TRANSGENIC MICE  MOUSE MODEL  NEURODEGENERATION  EXPRESSION  REDUCTION  MEMBRANE  MEMORY  ER  
The phenolic profile of walnut meal protein isolate and interaction of phenolics with walnut protein 期刊论文
FOOD RESEARCH INTERNATIONAL, 2023, 卷号: 170, 页码: 113042
作者:  Wang,Yuxi;  Tan,Bing;  Chen,Chi;  Zhang,Xudong;  Sun,Xiangjun
浏览  |  Adobe PDF(2848Kb)  |  收藏  |  浏览/下载:34/8  |  提交时间:2024/07/30
Walnut meal  Protein isolate  Phenolic compounds  Interaction mechanisms  Protein functional properties  AMINO-ACID-COMPOSITION  FUNCTIONAL-PROPERTIES  MOLECULAR DOCKING  ANTIOXIDANT ACTIVITY  BINDING INTERACTION  QUANTUM-MECHANICS  BETA-CASEIN  BIOACCESSIBILITY  HYDROLYSIS  PEPTIDES  
Anticarin-beta shows a promising anti-osteosarcoma effect by specifically inhibiting CCT4 to impair proteostasis 期刊论文
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 5, 页码: 2268-2279
作者:  Wang, Gan;  Zhang, Min;  Meng, Ping;  Long, Chengbo;  Luo, Xiaodong;  Yang, Xingwei;  Wang, Yunfei;  Zhang, Zhiye;  Mwangi, James;  Kamau, Peter Muiruri;  Dai, Zhi;  Ke, Zunfu;  Zhang, Yi;  Chen, Wenlin;  Zhao, Xudong;  Ge, Fei;  Lv, Qiumin;  Rong, Mingqiang;  Li, Dongsheng;  Jin, Yang;  Sheng, Xia;  Lai, Ren
浏览  |  Adobe PDF(4759Kb)  |  收藏  |  浏览/下载:104/19  |  提交时间:2024/04/30
Proteostasis  CCT  TRiC  Osteosarcoma  STAT3  Anticarin-beta  PDX model  CYTOSOLIC CHAPERONIN  CANCER-CELLS  COMPLEX  EXPRESSION  SURVIVAL  PROTEIN  TUBULIN  GROWTH  
Recent Studies on Protective Effects of Walnuts against Neuroinflammation 期刊论文
NUTRIENTS, 2022, 卷号: 14, 期号: 20, 页码: 4360
作者:  Tan, Bing;  Wang, Yuxi;  Zhang, Xudong;  Sun, Xiangjun
浏览  |  Adobe PDF(999Kb)  |  收藏  |  浏览/下载:121/14  |  提交时间:2024/04/30
walnuts  neuroinflammation  neurodegenerative diseases  oxidative stress  antioxidant activity  gut microbes  ALPHA-LINOLENIC ACID  BETA-AMYLOID PROTEIN  NF-KAPPA-B  OXIDATIVE STRESS  COGNITIVE IMPAIRMENT  MEDITERRANEAN DIET  INDUCED ACTIVATION  BV-2 MICROGLIA  ELLAGIC ACID  GALLIC ACID  
Bitter Melon and Diabetes Mellitus 期刊论文
FOOD REVIEWS INTERNATIONAL, 2021
作者:  Gao,Ya;  Li,Xian;  Huang,Yanjie;  Chen,Jianchao;  Qiu,Minghua
收藏  |  浏览/下载:104/0  |  提交时间:2022/04/02
Bitter melon  diabetes mellitus  crude extracts  phyto-metabolites  hypoglycemic mechanism  MOMORDICA-CHARANTIA L.  11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE-1  ALPHA-GLUCOSIDASE INHIBITION  INSULIN-RESISTANCE  ANTIDIABETIC ACTIVITIES  GUT MICROBIOTA  STRUCTURAL-CHARACTERIZATION  PHENOLIC-COMPOUNDS  OXIDATIVE STRESS  PROTEIN-KINASE  
Harpertrioate A, an A,B,D-seco-Limonoid with Promising Biological Activity against Alzheimer's Disease from Twigs of Harrisonia perforata (Blanco) Merr 期刊论文
ORGANIC LETTERS, 2021, 卷号: 23, 期号: 2, 页码: 262-267
作者:  Tang,Xiao-Han;  Luo,Rong-Can;  Ye,Mao-Sen;  Tang,Hong-Yu;  Ma,Yuan-Liang;  Chen,Yan-Ni;  Wang,Xin-Meng;  Lu,Qing-Yun;  Liu,Shuai;  Li,Xiao-Nian;  Yan,Ying;  Yang,Jing;  Ran,Xiao-Qian;  Fang,Xin;  Zhou,Yan;  Yao,Yong-Gang;  Di,Ying-Tong;  Hao,Xiao-Jiang
收藏  |  浏览/下载:102/0  |  提交时间:2022/04/02
AMYLOID PRECURSOR PROTEIN  INSULIN-DEGRADING ENZYME  BETA-PROTEIN  GEMFIBROZIL  PREVENTION  SECRETASE  ADAM10  MEN  
A new eudesmane sesquiterpenoid lactone from Chloranthus japonicus 期刊论文
CHINESE JOURNAL OF NATURAL MEDICINES, 2012, 卷号: 10, 期号: 1, 页码: 24-27
作者:  Fang Ping-Lei;  Liu Hai-Yang;  Zhong Hui-Min
Adobe PDF(285Kb)  |  收藏  |  浏览/下载:377/91  |  提交时间:2012/06/07
Acute Promyelocytic Leukemia  Activated Protein-kinase  Retinoic Acid  Signal-transduction  Alpha Oncoprotein  Pmlrar-alpha  C/ebp-beta  Product  Stress  H2o2  
Gastrodia elata modulates amyloid precursor protein cleavage and cognitive functions in mice 期刊论文
BIOSCIENCE TRENDS, 2011, 卷号: 5, 期号: 3, 页码: 129-138
作者:  Mishra, Manisha;  Huang, Junjie;  Lee, Yin Yeng;  Chua, Doreen See Kin;  Lin, Xiaoyan;  Hu, Jiang-Miao;  Heese, Klaus
浏览  |  Adobe PDF(389Kb)  |  收藏  |  浏览/下载:205/62  |  提交时间:2015/08/17
Alzheimer's Disease  Beta-amyloid Precursor Protein  Kampo  Neurodegeneration  Traditional Chinese Medicine