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中国科学院昆明植物研究所知识管理系统
Knowledge Management System of Kunming Institute of Botany,CAS
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Oligosaccharide Blocks PAR1 (Proteinase-Activated Receptor 1)-PAR4-Mediated Platelet Activation by Binding to Thrombin Exosite II and Impairs Thrombosis
期刊论文
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2023, 卷号: 43, 期号: 2, 页码: 253-266
作者:
Li,Sujuan
;
Wang,Weili
;
Lin,Lisha
;
Yang,Lian
;
Cai,Ying
;
Yang,Xingzhi
;
Zhang,Taocui
;
Xiao,Chuang
;
Yan,Hui
;
Gao,Na
;
Zhao,Jinhua
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浏览/下载:85/16
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提交时间:2024/05/09
oligosaccharide
platelet activation
receptor
protease-activated
thrombin thrombosis
ANTIPLATELET THERAPIES
ALLOSTERIC LINKAGE
TISSUE FACTOR
PROTEASE
VORAPAXAR
MECHANISM
REVEALS
SITE
Structural Characterization and Anticoagulant Activities of a Keratan Sulfate-like Polysaccharide from the Sea Cucumber Holothuria fuscopunctata
期刊论文
MARINE DRUGS, 2023, 卷号: 21, 期号: 12, 页码: 632
作者:
Chen,Ru
;
Wang,Weili
;
Yin,Ronghua
;
Pan,Ying
;
Xu,Chen
;
Gao,Na
;
Luo,Xiaodong
;
Zhao,Jinhua
;
Reyes,Fernando
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Adobe PDF(6775Kb)
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浏览/下载:81/24
  |  
提交时间:2024/05/09
aminoglycan
structural features
keratan sulfate
depolymerization
oligosaccharides
anticoagulant activity
INTRINSIC-FACTOR XASE
GLYCOSAMINOGLYCAN
OLIGOSACCHARIDES
DEPOLYMERIZATION
ELUCIDATION
DERIVATIVES
HEPARIN
Branched Chondroitin Sulfate Oligosaccharides Derived from the Sea Cucumber Acaudina molpadioides Stimulate Neurite Outgrowth
期刊论文
MARINE DRUGS, 2022, 卷号: 20, 期号: 10, 页码: 653
作者:
Wang, Weili
;
Mao, Hui
;
Li, Sujuan
;
Zhang, Longlong
;
Yang, Lian
;
Yin, Ronghua
;
Zhao, Jinhua
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Adobe PDF(5142Kb)
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浏览/下载:52/13
  |  
提交时间:2024/04/30
fucosylated chondroitin sulfate
sea cucumber
disaccharide branch
oligosaccharide
neurite outgrowth
stimulation
HIPPOCAMPAL-NEURONS
PROMOTING ACTIVITY
GLYCOSAMINOGLYCAN
DISACCHARIDE
INHIBITOR
Structural Characterization and Heparanase Inhibitory Activity of Fucosylated Glycosaminoglycan from Holothuria floridana
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 3, 页码: 162
作者:
Shi,Xiang
;
Guan,Ruowei
;
Zhou,Lutan
;
Zuo,Zhichuang
;
Tao,Xuelin
;
Wang,Pin
;
Zhou,Yanrong
;
Yin,Ronghua
;
Zhao,Longyan
;
Gao,Na
;
Zhao,Jinhua
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浏览/下载:178/0
  |  
提交时间:2022/04/02
Holothuria floridana
fucosylated glycosaminoglycans
oligosaccharide
chemical structure
heparanase
Structural characterization and anticoagulant analysis of the novel branched fucosylated glycosaminoglycan from sea cucumber Holothuria nobilis
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 269, 页码: 118290
作者:
Li,Shanni
;
Zhong,Wei
;
Pan,Ying
;
Lin,Lisha
;
Cai,Ying
;
Mao,Hui
;
Zhang,Taocui
;
Li,Sujuan
;
Chen,Ru
;
Zhou,Lutan
;
Wang,Weili
;
Cui,Qinghua
;
Yin,Ronghua
;
Huang,Shengxiong
;
Zhao,Jinhua
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Adobe PDF(2581Kb)
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浏览/下载:272/36
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提交时间:2022/04/02
Disaccharide branch
Fucosylated glycosaminoglycan
Holothuria nobilis
Oligosaccharide
Anticoagulant
INTRINSIC TENASE COMPLEX
CHONDROITIN SULFATE
ACAUDINA-MOLPADIOIDEA
FACTOR XASE
HEPARIN
DEPOLYMERIZATION
OLIGOSACCHARIDES
POLYSACCHARIDES
DERIVATIVES
Structural characterization of oligosaccharides from free radical depolymerized fucosylated glycosaminoglycan and suggested mechanism of depolymerization
期刊论文
CARBOHYDRATE POLYMERS, 2021, 卷号: 270, 页码: 118368
作者:
Chen,Ru
;
Yin,Ronghua
;
Li,Shanni
;
Pan,Ying
;
Mao,Hui
;
Cai,Ying
;
Lin,Lisha
;
Wang,Weili
;
Zhang,Taocui
;
Zhou,Lutan
;
Gao,Na
;
Luo,Xiaodong
;
Zhao,Jinhua
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Adobe PDF(3356Kb)
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浏览/下载:141/36
  |  
提交时间:2022/04/02
Fucosylated glycosaminoglycan
Free radical depolymerization
Chemical structure
Oligosaccharide
NMR
INTRINSIC TENASE COMPLEX
ANTICOAGULANT ACTIVITIES
SEA-CUCUMBER
CHONDROITIN SULFATE
PHYSICOCHEMICAL CHARACTERISTICS
FACTOR XASE
POLYSACCHARIDES
DERIVATIVES
HEPARIN
The Toxicology of Native Fucosylated Glycosaminoglycans and the Safety of Their Depolymerized Products as Anticoagulants
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 9, 页码: 487
作者:
Lin,Lisha
;
Li,Sujuan
;
Gao,Na
;
Wang,Weili
;
Zhang,Taocui
;
Yang,Lian
;
Yang,Xingzhi
;
Luo,Dan
;
Ji,Xu
;
Zhao,Jinhua
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Adobe PDF(2854Kb)
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浏览/下载:178/31
  |  
提交时间:2022/04/02
fucosylated glycosaminoglycan
anticoagulant
platelet aggregation
contact activation
hypotension
pulmonary embolism
CHONDROITIN SULFATE
CONTACT SYSTEM
COMPLEMENT
COAGULATION
ACTIVATION
ACCUMULATION
INVOLVEMENT
DERIVATIVES
KALLIKREIN
THROMBOSIS
Pharmacokinetics and Pharmacodynamics of a Depolymerized Glycosaminoglycan from Holothuria fuscopunctata, a Novel Anticoagulant Candidate, in Rats by Bioanalytical Methods
期刊论文
MARINE DRUGS, 2021, 卷号: 19, 期号: 4, 页码: 212
作者:
Liu,Shuang
;
Zhang,Taocui
;
Sun,Huifang
;
Lin,Lisha
;
Gao,Na
;
Wang,Weili
;
Li,Sujuan
;
Zhao,Jinhua
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Adobe PDF(1230Kb)
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  |  
浏览/下载:258/61
  |  
提交时间:2022/04/02
pharmacokinetics
pharmacodynamics
anticoagulant
fucosylated glycosaminoglycan
dHG-5
method validation
A new fucosylated glycosaminoglycan containing disaccharide branches from Acaudina molpadioides: Unusual structure and anti-intrinsic tenase activity
期刊论文
CARBOHYDRATE POLYMERS, 2020
作者:
Mao, Hui
;
Cai, Ying
;
Li, Shanni
;
Sun, Huifang
;
Lin, Lisha
;
Pan, Ying
;
Yang, Wenjiao
;
He, Zhicheng
;
Chen, Ru
;
Zhou, Lutan
;
Wang, Weili
;
Yin, Ronghua
;
Zhao, Jinhua
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Adobe PDF(2623Kb)
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浏览/下载:148/28
  |  
提交时间:2021/01/05
Characterization of the Hydrolysis Kinetics of Fucosylated Glycosaminoglycan in Mild Acid and Structures of the Resulting Oligosaccharides
期刊论文
MARINE DRUGS, 2020
作者:
Liu, Xixi
;
Zhang, Zhexian
;
Mao, Hui
;
Wang, Pin
;
Zuo, Zhichuang
;
Gao, Li
;
Shi, Xiang
;
Yin, Ronghua
;
Gao, Na
;
Zhao, Jinhua
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Adobe PDF(1321Kb)
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  |  
浏览/下载:201/65
  |  
提交时间:2021/01/05