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Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress 期刊论文
PHYTOMEDICINE, 2023, 卷号: 112, 页码: 154720
作者:  Niu,Zhenpeng;  Tang,Guihua;  Wang,Xuenan;  Yang,Xu;  Zhao,Yueqin;  Wang,Yinyuan;  Liu,Qin;  Zhang,Fan;  Zhao,Yuhan;  Ding,Xiao;  Hao,Xiaojiang
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Lysosomal biogenesis  Autophagy  TFEB  TFE3  ER stress  IVDD  STAT3  TFE3  
Discovery of Natural Potent HMG-CoA Reductase Degraders for Lowering Cholesterol 期刊论文
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023
作者:  Su,Xiao-Zheng;  Zhang,Lin-Fei;  Hu,Kun;  An,Yang;  Zhang,Qiao-Peng;  Tang,Jian-Wei;  Yan,Bing-Chao;  Li,Xing-Ren;  Cai,Jie;  Li,Xiao-Nian;  Sun,Han-Dong;  Jiang,Shi-You;  Puno,Pema-Tenzin
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Enzymes  Meroterpenoids  Natural Products  Proteomics  Semisynthesis  STATIN  FUNGUS  RISK  ACID  
Discovery of diverse sesquiterpenoids from Magnolia grandiflora with cytotoxic activities by inducing cell apoptosis 期刊论文
BIOORGANIC CHEMISTRY, 2023, 卷号: 139, 页码: 106707
作者:  Xu,Shuangyu;  Tang,Yunyan;  Li,Yanan;  Yang,Jue;  Gu,Wei;  Hao,Xiaojiang;  Yuan,Chunmao
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Magnolia grandiflora  Sesquiterpenoids  Isolation and structural modification  Cytotoxic activity  Apoptosis  LACTONES  DERIVATIVES  LEAVES  AGENTS  
Munronin V with 7/7/6 tricarbocyclic framework from Munronia henryi harms inhibits tau pathology by activating autophagy 期刊论文
ORGANIC & BIOMOLECULAR CHEMISTRY, 2023, 卷号: 21, 期号: 3, 页码: 514-519
作者:  Yan,Ying;  Ran,Xiaoqian;  Wang,Dan;  Zhang,Xiong;  Peng,Mingyou;  Yan,Xiaoyan;  Tang,Lei;  Liang,Hong;  Qin,Xujie;  Di,Ying-Tong;  Luo,Rongcan;  Hao,Xiao-Jiang;  Yao,Yong-Gang
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UBIQUITIN-PROTEASOME SYSTEM  ALZHEIMERS-DISEASE  CONSTITUENTS  LIMONOIDS  TFEB  NEURODEGENERATION  
Microbiota-derived short-chain fatty acids mediate the effects of dengzhan shengmai in ameliorating cerebral ischemia via the gut-brain axis 期刊论文
JOURNAL OF ETHNOPHARMACOLOGY, 2023, 卷号: 306, 页码: 116158
作者:  Guo,Hui-Hui;  Shen,Hao-Ran;  Tang,Ming-Ze;  Sheng,Ning;  Ding,Xiao;  Lin,Yuan;  Zhang,Jin-Lan;  Jiang,Jian-Dong;  Gao,Tian-Le;  Wang,Lu-Lu;  Han,Yan-Xing
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Dengzhan shengmai  Microbiota-gut-brain axis  Short-chain fatty acids  Cerebral ischemia  Gut barrier  Fecal microbiota transplantation  STROKE  SCUTELLARIN  
Five new limonoids isolated from Walsura robusta. 期刊论文
Natural products and bioprospecting, 2023, 卷号: 13, 期号: 1, 页码: 7-7
作者:  Hou, Li;  Mei, Cui-Xuan;  Yuan, Chun-Mao;  Tang, Gui-Hua;  Chen, Duo-Zhi;  Zhao, Qing;  He, Hong-Ping;  Cao, Ming-Ming;  Hao, Xiao-Jiang
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Arabidopsis AGAMOUS-LIKE16 and SUPPRESSOR OF CONSTANS1 regulate the genome-wide expression and flowering time 期刊论文
PLANT PHYSIOLOGY, 2023, 卷号: 192, 期号: 1, 页码: 154-169
作者:  Dong,Xue;  Zhang,Li-Ping;  Tang,Yin-Hua;  Yu,Dongmei;  Cheng,Fang;  Dong,Yin-Xin;  Jiang,Xiao-Dong;  Qian,Fu-Ming;  Guo,Zhen-Hua;  Hu,Jin-Yong
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FLORAL TRANSITION  SOC1  FLC  MICRORNA  PATHWAYS  PROTEIN  IDENTIFICATION  CONTRIBUTES  ANNOTATION  DETERMINES  
Quassinoids from Twigs of Harrisonia perforata (Blanco) Merr and Their Anti-Parkinson's Disease Effect 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 22, 页码: 16196
作者:  Cai,Min;  Bai,Xiao-Lin;  Zang,Hao-Jing;  Tang,Xiao-Han;  Yan,Ying;  Wan,Jia-Jia;  Peng,Min-You;  Liang,Hong;  Liu,Lin;  Guo,Feng;  Zhao,Pei-Ji;  Liao,Xun;  Di,Ying-Tong;  Hao,Xiao-Jiang
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Harrisonia perforata  quassinoid  simarubaceae  neuroprotection  PC12 cells  PINK1(B9) flies  PROMISING BIOLOGICAL-ACTIVITY  UNPRECEDENTED QUASSINOIDS  
Cytostatic Activity of Sanguinarine and a Cyanide Derivative in Human Erythroleukemia Cells Is Mediated by Suppression of c-MET/MAPK Signaling 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 9, 页码: 8113
作者:  Xu,Xinglian;  Deng,Lulu;  Tang,Yaling;  Li,Jiang;  Zhong,Ting;  Hao,Xiaojiang;  Fan,Yanhua;  Mu,Shuzhen
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leukemia  sanguinarine  c-MET  MAPK  PI3K/mTOR  STAT3  MET  
Jatrophane Diterpenoids from Euphorbia peplus Linn. as Activators of Autophagy and Inhibitors of Tau Pathology 期刊论文
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 2, 页码: 1088
作者:  Yan,Ying;  Zhou,Qi;  Ran,Xiaoqian;  Lu,Qingyun;  Zhang,Cuishan;  Peng,Mingyou;  Tang,Lei;  Luo,Rongcan;  Di,Yingtong;  Hao,Xiaojiang
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euphjatrophane  Euphorbia peplus  jatrophane diterpenoid  autophagy  Tau pathology  UBIQUITIN-PROTEASOME SYSTEM  MULTIDRUG-RESISTANCE  BIOLOGICAL-ACTIVITY  ALZHEIMERS-DISEASE  MODULATORS  CELLS