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Proteomic identification of the oncoprotein STAT3 as a target of a novel Skp1 inhibitor 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 2, 页码: 2681-2693
作者:  Cheng, Xin;  Liu, Yong-Qiang;  Wang, Gui-Zhen;  Yang, Li-Na;  Lu, Yong-Zhi;  Li, Xin-Chun;  Zhou, Bo;  Qu, Li-Wei;  Wang, Xiao-Lu;  Cheng, Yong-Xian;  Liu, Jinsong;  Tao, Sheng-Ce;  Zhou, Guang-Biao
浏览  |  Adobe PDF(7649Kb)  |  收藏  |  浏览/下载:228/27  |  提交时间:2017/04/18
Proteome Microarray  6-o-angeloylplenolin  Stat3 Inhibitor  Skp2  Lung Cancer  
microRNA-375 inhibits colorectal cancer cells proliferation by downregulating JAK2/STAT3 and MAP3K8/ERK signaling pathways 期刊论文
ONCOTARGET, 2017, 卷号: 8, 期号: 10, 页码: 16633-16641
作者:  Wei, Ran;  Yang, Qin;  Han, Bing;  Li, Yan;  Yao, Kun;  Yang, Xiuyu;  Chen, Zexi;  Yang, Shanshan;  Zhou, Jiaqi;  Li, Meizhang;  Yu, Haijing;  Yu, Min;  Cui, Qinghua
浏览  |  Adobe PDF(12068Kb)  |  收藏  |  浏览/下载:470/43  |  提交时间:2017/04/19
Microrna-375  Colorectal Cancer  Jak2/stat3 Pathway  Map3k8/erk Pathway  Atg7  
Eriocalyxin B, a natural diterpenoid, inhibited VEGF-induced angiogenesis and diminished angiogenesis-dependent breast tumor growth by suppressing VEGFR-2 signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 50, 页码: 82820-82835
作者:  Zhou, Xunian;  Yue, Grace Gar-Lee;  Liu, Minghua;  Zuo, Zhili;  Lee, Julia Kin-Ming;  Li, Mingyue;  Tsui, Stephen Kwok-Wing;  Fung, Kwok-Pui;  Sun, Handong;  Pu, Jianxin;  Lau, Clara Bik-San
浏览  |  Adobe PDF(13632Kb)  |  收藏  |  浏览/下载:409/52  |  提交时间:2017/02/28
Eriocalyxin b  Angiogenesis  Vascular Endothelial Growth Factor (Vegf)  Vascular Endothelial Growth Factor Receptor 2(Vegfr-2)  Breast Cancer  
CDDO-Me reveals USP7 as a novel target in ovarian cancer cells 期刊论文
Oncotarget, 2016, 卷号: 7, 期号: 47, 页码: 77096-77109
作者:  Qin, Dongjun;  Wang, Weiwei;  Lei, Hu;  Luo, Hao;  Cai, Haiyan;  Tang, Caixia;  Wu, Yunzhao;  Wang, Yingying;  Jin, Jin;  Xiao, Weilie;  Wang, Tongdan;  Ma, Chunmin;  Xu, Hanzhang;  Zhang, Jinfu;  Gao, Fenghou;  Wu, Ying-Li
浏览  |  Adobe PDF(8973Kb)  |  收藏  |  浏览/下载:259/101  |  提交时间:2017/02/14
Cddo-me  Ovarian Cancer  Usp7  Cetsa  Deubiquitinating Enzymes  
Cheliensisin A (Chel A) induces apoptosis in human bladder cancer cells by promoting PHLPP2 protein degradation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 41, 页码: 66689-66699
作者:  Zhang, Ruowen;  Che, Xun;  Zhang, Jingjie;  Li, Yang;  Li, Jingxia;  Deng, Xu;  Zhu, Junlan;  Jin, Honglei;  Zhao, Qinshi;  Huang, Chuanshu
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Chel a  Human Bladder Cancer  Apoptosis  Phlpp2  C-jun  
Momordin Ic, a new natural SENP1 inhibitor, inhibits prostate cancer cell proliferation 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 37, 页码: 58995-59005
作者:  Wu, Jingjing;  Lei, Hu;  Zhang, Jinfu;  Chen, Xiangyun;  Tang, Caixia;  Wang, Weiwei;  Xu, Hanzhang;  Xiao, Weilie;  Gu, Wenli;  Wu, Yingli
浏览  |  Adobe PDF(2389Kb)  |  收藏  |  浏览/下载:195/47  |  提交时间:2017/01/05
Momordin Ic  Senp1  Sumoylation  Proliferation  Prostate Cancer  
Bisleuconothine A, a bisindole alkaloid, inhibits colorectal cancer cell in vitro and in vivo targeting Wnt signaling 期刊论文
ONCOTARGET, 2016, 卷号: 7, 期号: 9, 页码: 10203-10214
作者:  Kong, Ling-Mei;  Feng, Tao;  Wang, Yuan-Yuan;  Li, Xing-Yao;  Ye, Zhen-Nan;  An, Tao;  Qing, Chen;  Luo, Xiao-Dong;  Li, Yan
浏览  |  Adobe PDF(7290Kb)  |  收藏  |  浏览/下载:289/58  |  提交时间:2016/08/22
Bisleuconothine a  Inhibitor  Wnt Signaling  Colorectal Cancer Cells  
Grifolin directly targets ERK1/2 to epigenetically suppress cancer cell metastasis 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 40, 页码: 42704-42716
作者:  Luo, Xiangjian;  Yang, Lifang;  Xiao, Lanbo;  Xia, Xiaofeng;  Dong, Xin;  Zhong, Juanfang;  Liu, Ying;  Li, Namei;  Chen, Ling;  Li, Hongde;  Li, Wei;  Liu, Wenbin;  Yu, Xinfang;  Chen, Hanyong;  Tang, Min;  Weng, Xinxian;  Yi, Wei;  Bode, Ann;  Dong, Zigang;  Liu, Jikai;  Cao, Ya
浏览  |  Adobe PDF(5262Kb)  |  收藏  |  浏览/下载:264/45  |  提交时间:2016/06/27
Grifolin  Erk1/2  Dnmt1  Metastasis  
Skp1 in lung cancer: clinical significance and therapeutic efficacy of its small molecule inhibitors 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 33, 页码: 34953-34967
作者:  Liu,Yong-Qiang;  Wang,Xiao-Lu;  Cheng,Xin;  Lu,Yong-Zhi;  Wang,Gui-Zhen;  Li,Xin-Chun;  Zhang,Jian;  Wen,Zhe-Sheng;  Huang,Zhi-Liang;  Gao,Qin-Lei;  Yang,Li-Na;  Cheng,Yong-Xian;  Tao,Sheng-Ce;  Liu,Jinsong;  Zhou,Guang-Biao
浏览  |  Adobe PDF(2162Kb)  |  收藏  |  浏览/下载:347/72  |  提交时间:2016/01/19
Skp1  Lung Cancer  Structure-based High-throughput Virtual Screening  Inhibitors  6-o-angeloylplenolin  
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNF alpha and ROS production 期刊论文
ONCOTARGET, 2015, 卷号: 6, 期号: 4, 页码: 1995-2008
作者:  Yu, Xinfang;  Deng, Qipan;  Li, Wei;  Xiao, Lanbo;  Luo, Xiangjian;  Liu, Xiaolan;  Yang, Lifang;  Peng, Songling;  Ding, Zhihui;  Feng, Tao;  Zhou, Jian;  Fan, Jia;  Bode, Ann M.;  Dong, Zigang;  Liu, Jikai;  Cao, Ya;  Liu,JK (reprint author),Chinese Acad Sci,Kunming Inst Bot,State Key Lab Phytochem & Plant Resources West Ch,Beijing 100864,Yunnan,Peoples R China.;  jkliu@mail.kib.ac.cn;  ycao98@vip.sina.com
浏览  |  Adobe PDF(2848Kb)  |  收藏  |  浏览/下载:476/67  |  提交时间:2015/06/29
Necoalbaconol  Necroptosis  Ripk  Tnf Alpha  Nf-kappa b Signaling Pathway  Ros